Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 126


Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity.

Krogsgaard M, Li QJ, Sumen C, Huppa JB, Huse M, Davis MM.

Nature. 2005 Mar 10;434(7030):238-43. Epub 2005 Feb 20.


CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement.

Stone JD, Stern LJ.

J Immunol. 2006 Feb 1;176(3):1498-505. Erratum in: J Immunol. 2006 Mar 15;176(6):3843.


Direct observation of ligand recognition by T cells.

Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM.

Nature. 2002 Oct 24;419(6909):845-9.


Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected].

Boniface JJ, Rabinowitz JD, Wülfing C, Hampl J, Reich Z, Altman JD, Kantor RM, Beeson C, McConnell HM, Davis MM.

Immunity. 1998 Oct;9(4):459-66. Erratum in: Immunity 1998 Dec;9(6):891.


Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes.

Barton GM, Beers C, deRoos P, Eastman SR, Gomez ME, Forbush KA, Rudensky AY.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6937-42.


CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.

Umeshappa CS, Huang H, Xie Y, Wei Y, Mulligan SJ, Deng Y, Xiang J.

J Immunol. 2009 Jan 1;182(1):193-206.


Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules.

Ge Q, Stone JD, Thompson MT, Cochran JR, Rushe M, Eisen HN, Chen J, Stern LJ.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13729-34. Epub 2002 Oct 8.


Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.

Crawford F, Kozono H, White J, Marrack P, Kappler J.

Immunity. 1998 Jun;8(6):675-82.


The immune function of MHC class II molecules mutated in the putative superdimer interface.

Hayball JD, Lake RA.

Mol Cell Biochem. 2005 May;273(1-2):1-9.


Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface.

Beeson C, Rabinowitz J, Tate K, Gütgemann I, Chien YH, Jones PP, Davis MM, McConnell HM.

J Exp Med. 1996 Aug 1;184(2):777-82.


T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state.

Yachi PP, Lotz C, Ampudia J, Gascoigne NR.

J Exp Med. 2007 Oct 29;204(11):2747-57. Epub 2007 Oct 22.


Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals.

Van Komen JS, Mishra S, Byrum J, Chichili GR, Yaciuk JC, Farris AD, Rodgers W.

J Immunol. 2007 Nov 15;179(10):6845-55.


Tandem peptide epitopes facilitate CD4-dependent activation of T cell clones.

Hayball JD, Fidler SJ, Palliser D, Rees AD, Lamb JR, Lake RA.

Immunol Cell Biol. 1997 Apr;75(2):148-53.


Interaction of retinal pigmented epithelial cells and CD4 T cells leads to T-cell anergy.

Gregerson DS, Heuss ND, Lew KL, McPherson SW, Ferrington DA.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4654-63.

Items per page

Supplemental Content

Write to the Help Desk