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Results: 1 to 20 of 135

1.

Survival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-activated bad kinase.

Jin Z, Xin M, Deng X.

J Biol Chem. 2005 Apr 22;280(16):16045-52. Epub 2005 Feb 10.

PMID:
15705582
[PubMed - indexed for MEDLINE]
Free Article
2.

NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop.

Shen J, Xu L, Owonikoko TK, Sun SY, Khuri FR, Curran WJ, Deng X.

Cancer Lett. 2012 May 1;318(1):106-13. doi: 10.1016/j.canlet.2011.12.008. Epub 2011 Dec 13.

PMID:
22178655
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis.

Jin Z, Gao F, Flagg T, Deng X.

J Biol Chem. 2004 May 28;279(22):23837-44. Epub 2004 Mar 22.

PMID:
15037618
[PubMed - indexed for MEDLINE]
Free Article
6.

Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains.

Xu L, Deng X.

J Biol Chem. 2006 Feb 17;281(7):4457-66. Epub 2005 Dec 16.

PMID:
16361262
[PubMed - indexed for MEDLINE]
Free Article
7.

PKC-ι promotes glioblastoma cell survival by phosphorylating and inhibiting BAD through a phosphatidylinositol 3-kinase pathway.

Desai S, Pillai P, Win-Piazza H, Acevedo-Duncan M.

Biochim Biophys Acta. 2011 Jun;1813(6):1190-7. doi: 10.1016/j.bbamcr.2011.03.007. Epub 2011 Mar 17.

PMID:
21419810
[PubMed - indexed for MEDLINE]
Free Article
9.

4-Methylnitrosamino-1-3-pyridyl-1-butanone (NNK) promotes lung cancer cell survival by stimulating thromboxane A2 and its receptor.

Huang RY, Li MY, Hsin MK, Underwood MJ, Ma LT, Mok TS, Warner TD, Chen GG.

Oncogene. 2011 Jan 6;30(1):106-16. doi: 10.1038/onc.2010.390. Epub 2010 Sep 6.

PMID:
20818420
[PubMed - indexed for MEDLINE]
10.
11.

Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.

Ho YS, Chen CH, Wang YJ, Pestell RG, Albanese C, Chen RJ, Chang MC, Jeng JH, Lin SY, Liang YC, Tseng H, Lee WS, Lin JK, Chu JS, Chen LC, Lee CH, Tso WL, Lai YC, Wu CH.

Toxicol Appl Pharmacol. 2005 Jun 1;205(2):133-48. Epub 2005 Jan 8.

PMID:
15893541
[PubMed - indexed for MEDLINE]
12.

Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.

Xin M, Gao F, May WS, Flagg T, Deng X.

J Biol Chem. 2007 Jul 20;282(29):21268-77. Epub 2007 May 24.

PMID:
17525161
[PubMed - indexed for MEDLINE]
Free Article
13.
15.

Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.

Shin VY, Jin HC, Ng EK, Yu J, Leung WK, Cho CH, Sung JJ.

Toxicol Appl Pharmacol. 2008 Dec 1;233(2):254-61. doi: 10.1016/j.taap.2008.08.012. Epub 2008 Sep 6.

PMID:
18805435
[PubMed - indexed for MEDLINE]
16.

p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway.

Tan Y, Ruan H, Demeter MR, Comb MJ.

J Biol Chem. 1999 Dec 3;274(49):34859-67.

PMID:
10574959
[PubMed - indexed for MEDLINE]
Free Article
17.

Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis.

Li MY, Yip J, Hsin MK, Mok TS, Wu Y, Underwood MJ, Chen GG.

Eur Respir J. 2008 Oct;32(4):911-23. doi: 10.1183/09031936.00064508. Epub 2008 May 28.

PMID:
18508827
[PubMed - indexed for MEDLINE]
Free Article
18.

Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling.

Baldwin RM, Garratt-Lalonde M, Parolin DA, Krzyzanowski PM, Andrade MA, Lorimer IA.

Oncogene. 2006 May 11;25(20):2909-19.

PMID:
16331246
[PubMed - indexed for MEDLINE]
19.

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.

West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, Harris C, Belinsky S, Dennis PA.

J Clin Invest. 2003 Jan;111(1):81-90.

PMID:
12511591
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells.

Stallings-Mann M, Jamieson L, Regala RP, Weems C, Murray NR, Fields AP.

Cancer Res. 2006 Feb 1;66(3):1767-74.

PMID:
16452237
[PubMed - indexed for MEDLINE]
Free Article

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