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Results: 1 to 20 of 109

1.

Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

Kagawa S, Sasaoka T, Yaguchi S, Ishihara H, Tsuneki H, Murakami S, Fukui K, Wada T, Kobayashi S, Kimura I, Kobayashi M.

J Clin Endocrinol Metab. 2005 May;90(5):2911-9. Epub 2005 Feb 1.

PMID:
15687335
[PubMed - indexed for MEDLINE]
2.

Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.

Sasaoka T, Kikuchi K, Wada T, Sato A, Hori H, Murakami S, Fukui K, Ishihara H, Aota R, Kimura I, Kobayashi M.

Endocrinology. 2003 Sep;144(9):4204-14.

PMID:
12933696
[PubMed - indexed for MEDLINE]
3.

Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors.

Ishihara H, Sasaoka T, Ishiki M, Wada T, Hori H, Kagawa S, Kobayashi M.

Mol Endocrinol. 2002 Oct;16(10):2371-81.

PMID:
12351701
[PubMed - indexed for MEDLINE]
4.

SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.

Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M.

Diabetologia. 2001 Oct;44(10):1258-67.

PMID:
11692174
[PubMed - indexed for MEDLINE]
5.

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.

Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.

Mol Cell Biol. 2001 Mar;21(5):1633-46.

PMID:
11238900
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.

Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M.

Endocrinology. 2004 Jul;145(7):3215-23. Epub 2004 Mar 24.

PMID:
15044364
[PubMed - indexed for MEDLINE]
7.

The SH2 domain containing inositol 5-phosphatase SHIP2 controls phosphatidylinositol 3,4,5-trisphosphate levels in CHO-IR cells stimulated by insulin.

Blero D, De Smedt F, Pesesse X, Paternotte N, Moreau C, Payrastre B, Erneux C.

Biochem Biophys Res Commun. 2001 Apr 6;282(3):839-43. Erratum in: Biochem Biophys Res Commun 2001 Jun 22;284(4):1090.

PMID:
11401540
[PubMed - indexed for MEDLINE]
8.

SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.

Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M.

J Biol Chem. 2004 Apr 9;279(15):14835-43. Epub 2004 Jan 26.

PMID:
14744864
[PubMed - indexed for MEDLINE]
Free Article
9.

Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling.

Ishihara H, Sasaoka T, Hori H, Wada T, Hirai H, Haruta T, Langlois WJ, Kobayashi M.

Biochem Biophys Res Commun. 1999 Jun 24;260(1):265-72.

PMID:
10381377
[PubMed - indexed for MEDLINE]
10.

The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells.

Pesesse X, Dewaste V, De Smedt F, Laffargue M, Giuriato S, Moreau C, Payrastre B, Erneux C.

J Biol Chem. 2001 Jul 27;276(30):28348-55. Epub 2001 May 10.

PMID:
11349134
[PubMed - indexed for MEDLINE]
Free Article
11.

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.

Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.

J Biol Chem. 2005 Jun 10;280(23):22523-9. Epub 2005 Apr 11.

PMID:
15824124
[PubMed - indexed for MEDLINE]
Free Article
12.

Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity.

Sasaoka T, Wada T, Tsuneki H.

Pharmacol Ther. 2006 Dec;112(3):799-809. Epub 2006 Jul 13. Review.

PMID:
16842857
[PubMed - indexed for MEDLINE]
13.

Association of the polymorphisms in the 5'-untranslated region of PTEN gene with type 2 diabetes in a Japanese population.

Ishihara H, Sasaoka T, Kagawa S, Murakami S, Fukui K, Kawagishi Y, Yamazaki K, Sato A, Iwata M, Urakaze M, Ishiki M, Wada T, Yaguchi S, Tsuneki H, Kimura I, Kobayashi M.

FEBS Lett. 2003 Nov 20;554(3):450-4.

PMID:
14623110
[PubMed - indexed for MEDLINE]
Free Article
14.

SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.

Wang Y, Keogh RJ, Hunter MG, Mitchell CA, Frey RS, Javaid K, Malik AB, Schurmans S, Tridandapani S, Marsh CB.

J Immunol. 2004 Dec 1;173(11):6820-30.

PMID:
15557176
[PubMed - indexed for MEDLINE]
Free Article
15.

Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl.

Mokhtari D, Al-Amin A, Turpaev K, Li T, Idevall-Hagren O, Li J, Wuttke A, Fred RG, Ravassard P, Scharfmann R, Tengholm A, Welsh N.

Diabetologia. 2013 Jun;56(6):1327-38. doi: 10.1007/s00125-013-2868-2. Epub 2013 Mar 5.

PMID:
23462796
[PubMed - indexed for MEDLINE]
16.

Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes.

Ikubo M, Wada T, Fukui K, Ishiki M, Ishihara H, Asano T, Tsuneki H, Sasaoka T.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E157-64. doi: 10.1152/ajpendo.90581.2008. Epub 2008 Nov 11.

PMID:
19001549
[PubMed - indexed for MEDLINE]
Free Article
17.

Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes.

Artemenko Y, Gagnon A, Ibrahim S, Sorisky A.

J Cell Physiol. 2007 Jun;211(3):598-607.

PMID:
17219406
[PubMed - indexed for MEDLINE]
18.

A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells.

Wisniewski D, Strife A, Swendeman S, Erdjument-Bromage H, Geromanos S, Kavanaugh WM, Tempst P, Clarkson B.

Blood. 1999 Apr 15;93(8):2707-20.

PMID:
10194451
[PubMed - indexed for MEDLINE]
Free Article
19.

The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners.

Onnockx S, De Schutter J, Blockmans M, Xie J, Jacobs C, Vanderwinden JM, Erneux C, Pirson I.

J Cell Physiol. 2008 Jan;214(1):260-72.

PMID:
17620296
[PubMed - indexed for MEDLINE]
20.

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