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Results: 1 to 20 of 152

1.

Regulation of cellular response to oncogenic and oxidative stress by Seladin-1.

Wu C, Miloslavskaya I, Demontis S, Maestro R, Galaktionov K.

Nature. 2004 Dec 2;432(7017):640-5.

PMID:
15577914
[PubMed - indexed for MEDLINE]
2.

Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress.

Kuehnle K, Crameri A, Kälin RE, Luciani P, Benvenuti S, Peri A, Ratti F, Rodolfo M, Kulic L, Heppner FL, Nitsch RM, Mohajeri MH.

Mol Cell Biol. 2008 Jan;28(2):539-50. Epub 2007 Nov 5.

PMID:
17984220
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation.

Lin AW, Lowe SW.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5025-30. Epub 2001 Apr 17.

PMID:
11309506
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Contribution of estrogen receptor alpha to oncogenic K-Ras-mediated NIH3T3 cell transformation and its implication for escape from senescence by modulating the p53 pathway.

Kato K, Horiuchi S, Takahashi A, Ueoka Y, Arima T, Matsuda T, Kato H, Nishida Ji J, Nakabeppu Y, Wake N.

J Biol Chem. 2002 Mar 29;277(13):11217-24. Epub 2002 Jan 7.

PMID:
11781307
[PubMed - indexed for MEDLINE]
Free Article
5.

[Seladin-1/DHCR24: a key protein of cell homeostasis and cholesterol biosynthesis].

Drzewińska J, Pułaski L, Soszyński M, Bartosz G.

Postepy Hig Med Dosw (Online). 2009 Jul 13;63:318-30. Review. Polish.

PMID:
19597241
[PubMed - indexed for MEDLINE]
Free Article
6.

Mdm2 ligase dead mutants did not act in a dominant negative manner to re-activate p53, but promoted tumor cell growth.

Swaroop M, Sun Y.

Anticancer Res. 2003 Jul-Aug;23(4):3167-74.

PMID:
12926050
[PubMed - indexed for MEDLINE]
7.

The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress.

Greeve I, Hermans-Borgmeyer I, Brellinger C, Kasper D, Gomez-Isla T, Behl C, Levkau B, Nitsch RM.

J Neurosci. 2000 Oct 1;20(19):7345-52.

PMID:
11007892
[PubMed - indexed for MEDLINE]
Free Article
8.

A modified p53 overcomes mdm2-mediated oncogenic transformation: a potential cancer therapeutic agent.

Lin J, Jin X, Page C, Sondak VK, Jiang G, Reynolds RK.

Cancer Res. 2000 Oct 15;60(20):5895-901.

PMID:
11059788
[PubMed - indexed for MEDLINE]
Free Article
9.

ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.

Sashida G, Liu Y, Elf S, Miyata Y, Ohyashiki K, Izumi M, Menendez S, Nimer SD.

Mol Cell Biol. 2009 Jul;29(13):3687-99. doi: 10.1128/MCB.01551-08. Epub 2009 Apr 20.

PMID:
19380490
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The ubiquitin ligase COP1 is a critical negative regulator of p53.

Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, O'Rourke K, Koeppen H, Dixit VM.

Nature. 2004 May 6;429(6987):86-92. Epub 2004 Apr 21.

PMID:
15103385
[PubMed - indexed for MEDLINE]
11.

The ability of E1A to rescue ras-induced premature senescence and confer transformation relies on inactivation of both p300/CBP and Rb family proteins.

Deng Q, Li Y, Tedesco D, Liao R, Fuhrmann G, Sun P.

Cancer Res. 2005 Sep 15;65(18):8298-307. Erratum in: Cancer Res. 2005 Nov 15;65(22):10635.

PMID:
16166306
[PubMed - indexed for MEDLINE]
Free Article
12.

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

Pantoja C, Serrano M.

Oncogene. 1999 Sep 2;18(35):4974-82.

PMID:
10490832
[PubMed - indexed for MEDLINE]
Free Article
13.

p53 in polyoma virus transformed REF52 cells.

Mor O, Read M, Fried M.

Oncogene. 1997 Dec 18;15(25):3113-9.

PMID:
9444959
[PubMed - indexed for MEDLINE]
Free Article
14.

Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX.

Hu B, Gilkes DM, Chen J.

Cancer Res. 2007 Sep 15;67(18):8810-7.

PMID:
17875722
[PubMed - indexed for MEDLINE]
Free Article
15.

The MDM2-p53 interaction.

Moll UM, Petrenko O.

Mol Cancer Res. 2003 Dec;1(14):1001-8. Review.

PMID:
14707283
[PubMed - indexed for MEDLINE]
Free Article
16.

Cellular senescence induced by p53-ras cooperation is independent of p21waf1 in murine embryo fibroblasts.

Castro ME, del Valle Guijarro M, Moneo V, Carnero A.

J Cell Biochem. 2004 Jun 1;92(3):514-24.

PMID:
15156563
[PubMed - indexed for MEDLINE]
17.

Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.

Vredeveld LC, Rowland BD, Douma S, Bernards R, Peeper DS.

Carcinogenesis. 2010 Feb;31(2):201-7. doi: 10.1093/carcin/bgp296. Epub 2009 Nov 25.

PMID:
19942610
[PubMed - indexed for MEDLINE]
Free Article
18.

Ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress.

Abad M, Menéndez C, Füchtbauer A, Serrano M, Füchtbauer EM, Palmero I.

J Biol Chem. 2007 Oct 19;282(42):31060-7. Epub 2007 Aug 10.

PMID:
17693408
[PubMed - indexed for MEDLINE]
Free Article
19.

Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway.

Bartholomew JN, Volonte D, Galbiati F.

Cancer Res. 2009 Apr 1;69(7):2878-86. doi: 10.1158/0008-5472.CAN-08-2857. Epub 2009 Mar 24.

PMID:
19318577
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.

Woo RA, Poon RY.

Genes Dev. 2004 Jun 1;18(11):1317-30.

PMID:
15175263
[PubMed - indexed for MEDLINE]
Free PMC Article

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