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Results: 1 to 20 of 431

1.

Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway.

Nakada D, Hirano Y, Sugimoto K.

Mol Cell Biol. 2004 Nov;24(22):10016-25.

PMID:
15509802
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends.

Hirano Y, Sugimoto K.

Mol Biol Cell. 2007 Jun;18(6):2026-36. Epub 2007 Mar 21.

PMID:
17377065
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Activation of protein kinase Tel1 through recognition of protein-bound DNA ends.

Fukunaga K, Kwon Y, Sung P, Sugimoto K.

Mol Cell Biol. 2011 May;31(10):1959-71. doi: 10.1128/MCB.05157-11. Epub 2011 Mar 14.

PMID:
21402778
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex.

Corda Y, Lee SE, Guillot S, Walther A, Sollier J, Arbel-Eden A, Haber JE, Géli V.

Mol Cell Biol. 2005 Dec;25(23):10652-64.

PMID:
16287875
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

Grenon M, Magill CP, Lowndes NF, Jackson SP.

FEMS Yeast Res. 2006 Aug;6(5):836-47.

PMID:
16879433
[PubMed - indexed for MEDLINE]
6.

Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks.

Mantiero D, Clerici M, Lucchini G, Longhese MP.

EMBO Rep. 2007 Apr;8(4):380-7. Epub 2007 Mar 9.

PMID:
17347674
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Three distinct modes of Mec1/ATR and Tel1/ATM activation illustrate differential checkpoint targeting during budding yeast early meiosis.

Cheng YH, Chuang CN, Shen HJ, Lin FM, Wang TF.

Mol Cell Biol. 2013 Aug;33(16):3365-76. doi: 10.1128/MCB.00438-13. Epub 2013 Jun 17.

PMID:
23775120
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends.

Clerici M, Trovesi C, Galbiati A, Lucchini G, Longhese MP.

EMBO J. 2014 Feb 3;33(3):198-216. doi: 10.1002/embj.201386041. Epub 2013 Dec 19.

PMID:
24357557
[PubMed - indexed for MEDLINE]
9.

The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling.

Clerici M, Mantiero D, Lucchini G, Longhese MP.

EMBO Rep. 2006 Feb;7(2):212-8.

PMID:
16374511
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.

Zou L, Elledge SJ.

Science. 2003 Jun 6;300(5625):1542-8.

PMID:
12791985
[PubMed - indexed for MEDLINE]
Free Article
11.

Effects of Saccharomyces cerevisiae mec1, tel1, and mre11 mutations on spontaneous and methylmethane sulfonate-induced genome instability.

Suetomi K, Mochizuki M, Suzuki S, Yamamoto H, Yamamoto K.

Genes Genet Syst. 2010 Feb;85(1):1-8.

PMID:
20410660
[PubMed - indexed for MEDLINE]
Free Article
12.

Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins.

Lisby M, Barlow JH, Burgess RC, Rothstein R.

Cell. 2004 Sep 17;118(6):699-713.

PMID:
15369670
[PubMed - indexed for MEDLINE]
Free Article
13.

Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.

Limbo O, Porter-Goff ME, Rhind N, Russell P.

Mol Cell Biol. 2011 Feb;31(3):573-83. doi: 10.1128/MCB.00994-10. Epub 2010 Nov 22.

PMID:
21098122
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR).

Gray S, Allison RM, Garcia V, Goldman AS, Neale MJ.

Open Biol. 2013 Jul 31;3(7):130019. doi: 10.1098/rsob.130019.

PMID:
23902647
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation.

Baroni E, Viscardi V, Cartagena-Lirola H, Lucchini G, Longhese MP.

Mol Cell Biol. 2004 May;24(10):4151-65.

PMID:
15121837
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.

Kondo T, Matsumoto K, Sugimoto K.

Mol Cell Biol. 1999 Feb;19(2):1136-43.

PMID:
9891048
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A DNA damage response pathway controlled by Tel1 and the Mre11 complex.

Usui T, Ogawa H, Petrini JH.

Mol Cell. 2001 Jun;7(6):1255-66.

PMID:
11430828
[PubMed - indexed for MEDLINE]
Free Article
18.

Processing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.

Ghodke I, Muniyappa K.

J Biol Chem. 2013 Apr 19;288(16):11273-86. doi: 10.1074/jbc.M112.439315. Epub 2013 Feb 26.

PMID:
23443654
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism.

Nakada D, Matsumoto K, Sugimoto K.

Genes Dev. 2003 Aug 15;17(16):1957-62.

PMID:
12923051
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage.

Nakada D, Hirano Y, Tanaka Y, Sugimoto K.

Mol Biol Cell. 2005 Nov;16(11):5227-35. Epub 2005 Sep 7.

PMID:
16148046
[PubMed - indexed for MEDLINE]
Free PMC Article

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