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Items: 1 to 20 of 181

1.

Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells.

Jimenez-Lopez JM, Cederbaum AI.

J Pharmacol Exp Ther. 2005 Mar;312(3):998-1006. Epub 2004 Oct 19.

2.

Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity.

Jimenez-Lopez JM, Cederbaum AI.

Free Radic Biol Med. 2004 Feb 1;36(3):359-70.

PMID:
15036355
3.

Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity.

Caro AA, Cederbaum AI.

J Pharmacol Exp Ther. 2006 Jul;318(1):360-72. Epub 2006 Apr 19.

4.

Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity.

Pérez MJ, Cederbaum AI.

Free Radic Biol Med. 2003 Feb 15;34(4):443-55.

PMID:
12566070
5.
6.

Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells.

Caro AA, Cederbaum AI.

J Biol Chem. 2003 Sep 5;278(36):33866-77. Epub 2003 Jun 17.

7.

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.

Wu D, Cederbaum A.

Toxicol Appl Pharmacol. 2006 Oct 15;216(2):282-92. Epub 2006 Jul 1.

PMID:
16938321
8.

Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells.

Caro AA, Cederbaum AI.

J Biol Chem. 2002 Jan 4;277(1):104-13. Epub 2001 Oct 31.

9.

Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.

Pérez MJ, Cederbaum AI.

Hepatology. 2003 Jun;37(6):1395-404.

PMID:
12774019
10.

Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.

Gong P, Cederbaum AI, Nieto N.

Free Radic Biol Med. 2004 Feb 1;36(3):307-18.

PMID:
15036350
11.

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.

Wu D, Cederbaum AI.

Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G674-84. Epub 2005 Nov 23.

12.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018
13.
14.

Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity.

Gong P, Cederbaum AI.

J Biol Chem. 2006 May 26;281(21):14573-9. Epub 2006 Mar 21.

15.
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17.

Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway.

Gong P, Cederbaum AI, Nieto N.

J Biol Chem. 2003 Aug 8;278(32):29693-700. Epub 2003 May 30.

18.

Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity.

Pérez MJ, Cederbaum AI.

Free Radic Biol Med. 2002 Jul 1;33(1):111-27.

PMID:
12086689
20.

CYP2E1-dependent toxicity and oxidative stress in HepG2 cells.

Cederbaum AI, Wu D, Mari M, Bai J.

Free Radic Biol Med. 2001 Dec 15;31(12):1539-43. Review.

PMID:
11744327
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