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Results: 1 to 20 of 91

1.

Chk1 versus Cdc25: chking one's levels of cellular proliferation.

Lam MH, Rosen JM.

Cell Cycle. 2004 Nov;3(11):1355-7. Epub 2004 Nov 10. Review.

PMID:
15483403
[PubMed - indexed for MEDLINE]
Free Article
2.

Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.

Jin J, Ang XL, Ye X, Livingstone M, Harper JW.

J Biol Chem. 2008 Jul 11;283(28):19322-8. doi: 10.1074/jbc.M802474200. Epub 2008 May 13.

PMID:
18480045
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism.

Uto K, Inoue D, Shimuta K, Nakajo N, Sagata N.

EMBO J. 2004 Aug 18;23(16):3386-96. Epub 2004 Jul 22.

PMID:
15272308
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

Goto H, Izawa I, Li P, Inagaki M.

Cancer Sci. 2012 Jul;103(7):1195-200. doi: 10.1111/j.1349-7006.2012.02280.x. Epub 2012 Apr 23. Review.

PMID:
22435685
[PubMed - indexed for MEDLINE]
6.

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.

Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ.

Science. 1997 Sep 5;277(5331):1497-501.

PMID:
9278511
[PubMed - indexed for MEDLINE]
Free Article
7.

Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.

Demidova AR, Aau MY, Zhuang L, Yu Q.

J Biol Chem. 2009 Feb 13;284(7):4132-9. doi: 10.1074/jbc.M808118200. Epub 2008 Dec 7.

PMID:
19060337
[PubMed - indexed for MEDLINE]
Free Article
8.

Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.

Hutchins JR, Dikovskaya D, Clarke PR.

Mol Biol Cell. 2003 Oct;14(10):4003-14. Epub 2003 Jul 11. Erratum in: Mol Biol Cell. 2005 Mar;16(3):1568.

PMID:
14517314
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01.

Graves PR, Yu L, Schwarz JK, Gales J, Sausville EA, O'Connor PM, Piwnica-Worms H.

J Biol Chem. 2000 Feb 25;275(8):5600-5.

PMID:
10681541
[PubMed - indexed for MEDLINE]
Free Article
10.

ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.

Sørensen CS, Syljuåsen RG, Lukas J, Bartek J.

Cell Cycle. 2004 Jul;3(7):941-5. Epub 2004 Jul 13.

PMID:
15190204
[PubMed - indexed for MEDLINE]
Free Article
11.

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.

Chen Z, Xiao Z, Gu WZ, Xue J, Bui MH, Kovar P, Li G, Wang G, Tao ZF, Tong Y, Lin NH, Sham HL, Wang JY, Sowin TJ, Rosenberg SH, Zhang H.

Int J Cancer. 2006 Dec 15;119(12):2784-94.

PMID:
17019715
[PubMed - indexed for MEDLINE]
12.

Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.

Lee HJ, Hwang HI, Jang YJ.

Cell Cycle. 2010 Jun 15;9(12):2389-98. Epub 2010 Jun 15.

PMID:
20581453
[PubMed - indexed for MEDLINE]
Free Article
13.

In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targets.

Kiyokawa H, Ray D.

Anticancer Agents Med Chem. 2008 Dec;8(8):832-6. Review.

PMID:
19075565
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis.

Busino L, Chiesa M, Draetta GF, Donzelli M.

Oncogene. 2004 Mar 15;23(11):2050-6. Review.

PMID:
15021892
[PubMed - indexed for MEDLINE]
15.

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW.

Genes Dev. 2003 Dec 15;17(24):3062-74. Epub 2003 Dec 17.

PMID:
14681206
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.

Collis SJ, Barber LJ, Clark AJ, Martin JS, Ward JD, Boulton SJ.

Nat Cell Biol. 2007 Apr;9(4):391-401. Epub 2007 Mar 25.

PMID:
17384638
[PubMed - indexed for MEDLINE]
17.

CDC25A and B dual-specificity phosphatase inhibitors: potential agents for cancer therapy.

Lavecchia A, Di Giovanni C, Novellino E.

Curr Med Chem. 2009;16(15):1831-49. Review.

PMID:
19442149
[PubMed - indexed for MEDLINE]
18.

The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.

Zhang Y, Qu D, Morris EJ, O'Hare MJ, Callaghan SM, Slack RS, Geller HM, Park DS.

J Neurosci. 2006 Aug 23;26(34):8819-28.

PMID:
16928871
[PubMed - indexed for MEDLINE]
Free Article
19.

Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.

Shimuta K, Nakajo N, Uto K, Hayano Y, Okazaki K, Sagata N.

EMBO J. 2002 Jul 15;21(14):3694-703.

PMID:
12110582
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest.

Wang XQ, Stanbridge EJ, Lao X, Cai Q, Fan ST, Redpath JL.

Radiat Res. 2007 Dec;168(6):706-15.

PMID:
18088187
[PubMed - indexed for MEDLINE]

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