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Results: 1 to 20 of 136

1.

Critical catalytic functional groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.

Blanco J, Moore RA, Faehnle CR, Viola RE.

Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1808-15. Epub 2004 Sep 23.

PMID:
15388927
[PubMed - indexed for MEDLINE]
2.

The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.

Blanco J, Moore RA, Faehnle CR, Coe DM, Viola RE.

Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1388-95. Epub 2004 Jul 21.

PMID:
15272161
[PubMed - indexed for MEDLINE]
3.

Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.

Faehnle CR, Blanco J, Viola RE.

Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2320-4. Epub 2004 Nov 26.

PMID:
15583380
[PubMed - indexed for MEDLINE]
4.

Capture of an intermediate in the catalytic cycle of L-aspartate-beta-semialdehyde dehydrogenase.

Blanco J, Moore RA, Viola RE.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12613-7. Epub 2003 Oct 14.

PMID:
14559965
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.

Faehnle CR, Le Coq J, Liu X, Viola RE.

J Biol Chem. 2006 Oct 13;281(41):31031-40. Epub 2006 Aug 8.

PMID:
16895909
[PubMed - indexed for MEDLINE]
Free Article
6.

Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.

Arachea BT, Liu X, Pavlovsky AG, Viola RE.

Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):205-12. doi: 10.1107/S0907444909052834. Epub 2010 Jan 22.

PMID:
20124701
[PubMed - indexed for MEDLINE]
7.

The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.

Viola RE, Liu X, Ohren JF, Faehnle CR.

Acta Crystallogr D Biol Crystallogr. 2008 Mar;64(Pt 3):321-30. doi: 10.1107/S0907444907068552. Epub 2008 Feb 20.

PMID:
18323627
[PubMed - indexed for MEDLINE]
8.

A structural basis for the mechanism of aspartate-beta-semialdehyde dehydrogenase from Vibrio cholerae.

Blanco J, Moore RA, Kabaleeswaran V, Viola RE.

Protein Sci. 2003 Jan;12(1):27-33.

PMID:
12493825
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase.

Hadfield A, Shammas C, Kryger G, Ringe D, Petsko GA, Ouyang J, Viola RE.

Biochemistry. 2001 Dec 4;40(48):14475-83.

PMID:
11724560
[PubMed - indexed for MEDLINE]
10.

Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv.

Vyas R, Tewari R, Weiss MS, Karthikeyan S.

Acta Crystallogr D Biol Crystallogr. 2012 Jun;68(Pt 6):671-9. doi: 10.1107/S0907444912007330. Epub 2012 May 17.

PMID:
22683789
[PubMed - indexed for MEDLINE]
11.

Identification of an essential cysteine in the reaction catalyzed by aspartate-beta-semialdehyde dehydrogenase from Escherichia coli.

Karsten WE, Viola RE.

Biochim Biophys Acta. 1992 May 22;1121(1-2):234-8.

PMID:
1350921
[PubMed - indexed for MEDLINE]
12.

Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+).

Cherney LT, Cherney MM, Garen CR, Niu C, Moradian F, James MN.

J Mol Biol. 2007 Apr 13;367(5):1357-69. Epub 2007 Jan 20.

PMID:
17316682
[PubMed - indexed for MEDLINE]
13.

Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis.

Hadfield A, Kryger G, Ouyang J, Petsko GA, Ringe D, Viola R.

J Mol Biol. 1999 Jun 18;289(4):991-1002.

PMID:
10369777
[PubMed - indexed for MEDLINE]
14.

Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.

Pillai B, Cherney M, Diaper CM, Sutherland A, Blanchard JS, Vederas JC, James MN.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):547-53. Epub 2007 Sep 17.

PMID:
17889830
[PubMed - indexed for MEDLINE]
15.

Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.

Puthan Veetil V, Raj H, Quax WJ, Janssen DB, Poelarends GJ.

FEBS J. 2009 Jun;276(11):2994-3007. doi: 10.1111/j.1742-4658.2009.07015.x. Epub 2009 Apr 16.

PMID:
19490103
[PubMed - indexed for MEDLINE]
16.

High-resolution structures reveal details of domain closure and "half-of-sites-reactivity" in Escherichia coli aspartate beta-semialdehyde dehydrogenase.

Nichols CE, Dhaliwal B, Lockyer M, Hawkins AR, Stammers DK.

J Mol Biol. 2004 Aug 13;341(3):797-806.

PMID:
15288787
[PubMed - indexed for MEDLINE]
17.

Molecular modelling and comparative structural account of aspartyl beta-semialdehyde dehydrogenase of Mycobacterium tuberculosis (H37Rv).

Singh A, Kushwaha HR, Sharma P.

J Mol Model. 2008 Apr;14(4):249-63. doi: 10.1007/s00894-008-0267-2. Epub 2008 Jan 31.

PMID:
18236087
[PubMed - indexed for MEDLINE]
18.

Use of structural comparisons to select mutagenic targets in aspartate-beta-semialdehyde dehydrogenase.

Ouyang J, Viola RE.

Biochemistry. 1995 May 16;34(19):6394-9.

PMID:
7756269
[PubMed - indexed for MEDLINE]
19.

A new branch in the family: structure of aspartate-beta-semialdehyde dehydrogenase from Methanococcus jannaschii.

Faehnle CR, Ohren JF, Viola RE.

J Mol Biol. 2005 Nov 11;353(5):1055-68. Epub 2005 Sep 29.

PMID:
16225889
[PubMed - indexed for MEDLINE]
20.

Expression and purification of aspartate beta-semialdehyde dehydrogenase from infectious microorganisms.

Moore RA, Bocik WE, Viola RE.

Protein Expr Purif. 2002 Jun;25(1):189-94.

PMID:
12071715
[PubMed - indexed for MEDLINE]

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