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Results: 1 to 20 of 219

1.

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.

Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, Yamamoto M, Terai K, Matsuda M, Inoue J, Uematsu S, Takeuchi O, Akira S.

Nat Immunol. 2004 Oct;5(10):1061-8. Epub 2004 Sep 7.

PMID:
15361868
[PubMed - indexed for MEDLINE]
2.

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.

J Exp Med. 2005 Mar 21;201(6):915-23. Epub 2005 Mar 14.

PMID:
15767370
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.

Honda K, Yanai H, Mizutani T, Negishi H, Shimada N, Suzuki N, Ohba Y, Takaoka A, Yeh WC, Taniguchi T.

Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15416-21. Epub 2004 Oct 18.

PMID:
15492225
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.

Sirén J, Pirhonen J, Julkunen I, Matikainen S.

J Immunol. 2005 Feb 15;174(4):1932-7.

PMID:
15699120
[PubMed - indexed for MEDLINE]
Free Article
7.

Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4.

Doyle SE, O'Connell R, Vaidya SA, Chow EK, Yee K, Cheng G.

J Immunol. 2003 Apr 1;170(7):3565-71.

PMID:
12646618
[PubMed - indexed for MEDLINE]
Free Article
8.

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT.

J Biol Chem. 2005 Apr 29;280(17):17005-12. Epub 2005 Jan 28.

PMID:
15695821
[PubMed - indexed for MEDLINE]
Free Article
9.

Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation.

Hoshino K, Kaisho T, Iwabe T, Takeuchi O, Akira S.

Int Immunol. 2002 Oct;14(10):1225-31.

PMID:
12356687
[PubMed - indexed for MEDLINE]
Free Article
10.

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.

Osterlund P, Veckman V, Sirén J, Klucher KM, Hiscott J, Matikainen S, Julkunen I.

J Virol. 2005 Aug;79(15):9608-17.

PMID:
16014923
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.

Huang LY, Aliberti J, Leifer CA, Segal DM, Sher A, Golenbock DT, Golding B.

J Immunol. 2003 Aug 1;171(3):1441-6.

PMID:
12874236
[PubMed - indexed for MEDLINE]
Free Article
12.

Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration.

Seki E, Tsutsui H, Iimuro Y, Naka T, Son G, Akira S, Kishimoto T, Nakanishi K, Fujimoto J.

Hepatology. 2005 Mar;41(3):443-50.

PMID:
15723296
[PubMed - indexed for MEDLINE]
13.

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes.

Kawai T, Takeuchi O, Fujita T, Inoue J, Mühlradt PF, Sato S, Hoshino K, Akira S.

J Immunol. 2001 Nov 15;167(10):5887-94.

PMID:
11698465
[PubMed - indexed for MEDLINE]
Free Article
14.

Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice.

Seki E, Tsutsui H, Tsuji NM, Hayashi N, Adachi K, Nakano H, Futatsugi-Yumikura S, Takeuchi O, Hoshino K, Akira S, Fujimoto J, Nakanishi K.

J Immunol. 2002 Oct 1;169(7):3863-8.

PMID:
12244183
[PubMed - indexed for MEDLINE]
Free Article
15.

IRF-7 is the master regulator of type-I interferon-dependent immune responses.

Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.

Nature. 2005 Apr 7;434(7034):772-7. Epub 2005 Mar 30.

PMID:
15800576
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.

Pfaller CK, Conzelmann KK.

J Virol. 2008 Dec;82(24):12365-73. doi: 10.1128/JVI.01321-08. Epub 2008 Oct 15.

PMID:
18922877
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

Baetz A, Frey M, Heeg K, Dalpke AH.

J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.

PMID:
15491991
[PubMed - indexed for MEDLINE]
Free Article
19.

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus.

Hornung V, Schlender J, Guenthner-Biller M, Rothenfusser S, Endres S, Conzelmann KK, Hartmann G.

J Immunol. 2004 Nov 15;173(10):5935-43.

PMID:
15528327
[PubMed - indexed for MEDLINE]
Free Article
20.

IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism.

Stockinger S, Reutterer B, Schaljo B, Schellack C, Brunner S, Materna T, Yamamoto M, Akira S, Taniguchi T, Murray PJ, Müller M, Decker T.

J Immunol. 2004 Dec 15;173(12):7416-25.

PMID:
15585867
[PubMed - indexed for MEDLINE]
Free Article

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