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Items: 1 to 20 of 221

1.

Effect of nucleoside reverse transcriptase inhibitors on mitochondrial DNA synthesis in rats and humans.

Collins ML, Sondel N, Cesar D, Hellerstein MK.

J Acquir Immune Defic Syndr. 2004 Sep 1;37(1):1132-9.

PMID:
15319672
2.

Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.

Chan SS, Santos JH, Meyer JN, Mandavilli BS, Cook DL Jr, McCash CL, Kissling GE, Nyska A, Foley JF, van Houten B, Copeland WC, Walker VE, Witt KL, Bishop JB.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):190-200.

PMID:
16395692
3.

Site specific alterations of adipose tissue mitochondria in 3'-azido-3'-deoxythymidine (AZT)-treated rats: an early stage in lipodystrophy?

Deveaud C, Beauvoit B, Hagry S, Galinier A, Carrière A, Salin B, Schaeffer J, Caspar-Bauguil S, Fernandez Y, Gordien JB, Breilh D, Penicaud L, Casteilla L, Rigoulet M.

Biochem Pharmacol. 2005 Jul 1;70(1):90-101.

PMID:
15894294
4.

Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients.

Maagaard A, Holberg-Petersen M, Kollberg G, Oldfors A, Sandvik L, Bruun JN.

Antivir Ther. 2006;11(5):601-8.

PMID:
16964828
5.

Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells.

Pan-Zhou XR, Cui L, Zhou XJ, Sommadossi JP, Darley-Usmar VM.

Antimicrob Agents Chemother. 2000 Mar;44(3):496-503.

6.

Measurement of mitochondrial DNA synthesis in vivo using a stable isotope-mass spectrometric technique.

Collins ML, Eng S, Hoh R, Hellerstein MK.

J Appl Physiol (1985). 2003 Jun;94(6):2203-11. Epub 2003 Jan 31.

7.

Evidence of nucleoside analogue reverse transcriptase inhibitor--associated genetic and structural defects of mitochondria in adipose tissue of HIV-infected patients.

Walker UA, Bickel M, Lütke Volksbeck SI, Ketelsen UP, Schöfer H, Setzer B, Venhoff N, Rickerts V, Staszewski S.

J Acquir Immune Defic Syndr. 2002 Feb 1;29(2):117-21.

PMID:
11832679
8.

Role of pyrimidine depletion in the mitochondrial cardiotoxicity of nucleoside analogue reverse transcriptase inhibitors.

Balcarek K, Venhoff N, Deveaud C, Beauvoit B, Bonnet J, Kirschner J, Venhoff AC, Lebrecht D, Walker UA.

J Acquir Immune Defic Syndr. 2010 Dec 15;55(5):550-7. doi: 10.1097/QAI.0b013e3181f25946.

PMID:
20827217
9.

Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.

Walker DM, Poirier MC, Campen MJ, Cook DL Jr, Divi RL, Nagashima K, Lund AK, Cossey PY, Hahn FF, Walker VE.

Cardiovasc Toxicol. 2004;4(2):133-53.

PMID:
15371630
10.

Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors.

Divi RL, Leonard SL, Kuo MM, Walker BL, Orozco CC, St Claire MC, Nagashima K, Harbaugh SW, Harbaugh JW, Thamire C, Sable CA, Poirier MC.

Cardiovasc Toxicol. 2005;5(3):333-46.

PMID:
16244378
11.

Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure.

Gerschenson M, Poirier MC.

Ann N Y Acad Sci. 2000 Nov;918:269-81.

PMID:
11131713
12.

Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments.

Note R, Maisonneuve C, Lettéron P, Peytavin G, Djouadi F, Igoudjil A, Guimont MC, Biour M, Pessayre D, Fromenty B.

Antimicrob Agents Chemother. 2003 Nov;47(11):3384-92.

13.

Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver.

de la Asunción JG, del Olmo ML, Sastre J, Pallardó FV, Viña J.

Hepatology. 1999 Mar;29(3):985-7.

PMID:
10051507
14.

Uridine abrogates mitochondrial toxicity related to nucleoside analogue reverse transcriptase inhibitors in HepG2 cells.

Walker UA, Venhoff N, Koch EC, Olschewski M, Schneider J, Setzer B.

Antivir Ther. 2003 Oct;8(5):463-70.

PMID:
14640394
15.

Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver.

Desai VG, Lee T, Delongchamp RR, Leakey JE, Lewis SM, Lee F, Moland CL, Branham WS, Fuscoe JC.

Mitochondrion. 2008 Mar;8(2):181-95. doi: 10.1016/j.mito.2008.01.002. Epub 2008 Feb 1.

PMID:
18313992
16.

Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells.

Benbrik E, Chariot P, Bonavaud S, Ammi-Saïd M, Frisdal E, Rey C, Gherardi R, Barlovatz-Meimon G.

J Neurol Sci. 1997 Jul;149(1):19-25.

PMID:
9168161
17.

Deficit in cytochrome c oxidase activity induced in rat sperm mitochondria by in vivo exposure to zidovudine.

Leandri RD, Dulious E, Benbrik E, Jouannet P, De Almeida M.

Int J Androl. 2003 Oct;26(5):305-9. Erratum in: Int J Androl. 2003 Dec;26(6):375.

PMID:
14511219
19.

Improvement of mitochondrial toxicity in patients receiving a nucleoside reverse-transcriptase inhibitor-sparing strategy: results from the Multicenter Study with Nevirapine and Kaletra (MULTINEKA).

Negredo E, Miró O, Rodríguez-Santiago B, Garrabou G, Estany C, Masabeu A, Force L, Barrufet P, Cucurull J, Domingo P, Alonso-Villaverde C, Bonjoch A, Morén C, Pérez-Alvarez N, Clotet B; MULTINEKA Study Group.

Clin Infect Dis. 2009 Sep 15;49(6):892-900. doi: 10.1086/605440.

20.

Effect of short-term exposure to zidovudine (AZT) on the expression of mitochondria-related genes in skeletal muscle of neonatal mice.

Desai VG, Lee T, Moland CL, Branham WS, Von Tungeln LS, Beland FA, Fuscoe JC.

Mitochondrion. 2009 Feb;9(1):9-16. doi: 10.1016/j.mito.2008.09.002. Epub 2008 Sep 13.

PMID:
18824140
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