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Items: 1 to 20 of 254

1.

Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes.

Walton FS, Harmon AW, Paul DS, Drobná Z, Patel YM, Styblo M.

Toxicol Appl Pharmacol. 2004 Aug 1;198(3):424-33.

PMID:
15276423
2.

Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.

Paul DS, Harmon AW, Devesa V, Thomas DJ, Stýblo M.

Environ Health Perspect. 2007 May;115(5):734-42. Epub 2007 Jan 29.

3.

Methylated trivalent arsenicals are potent inhibitors of glucose stimulated insulin secretion by murine pancreatic islets.

Douillet C, Currier J, Saunders J, Bodnar WM, Matoušek T, Stýblo M.

Toxicol Appl Pharmacol. 2013 Feb 15;267(1):11-5. doi: 10.1016/j.taap.2012.12.007. Epub 2012 Dec 20.

4.

Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes.

Vega L, Styblo M, Patterson R, Cullen W, Wang C, Germolec D.

Toxicol Appl Pharmacol. 2001 May 1;172(3):225-32.

PMID:
11312651
5.

Metabolism of arsenic in primary cultures of human and rat hepatocytes.

Styblo M, Del Razo LM, LeCluyse EL, Hamilton GA, Wang C, Cullen WR, Thomas DJ.

Chem Res Toxicol. 1999 Jul;12(7):560-5.

PMID:
10409394
6.

Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells.

Styblo M, Del Razo LM, Vega L, Germolec DR, LeCluyse EL, Hamilton GA, Reed W, Wang C, Cullen WR, Thomas DJ.

Arch Toxicol. 2000 Aug;74(6):289-99.

PMID:
11005674
7.

Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.

Chen GQ, Zhou L, Styblo M, Walton F, Jing Y, Weinberg R, Chen Z, Waxman S.

Cancer Res. 2003 Apr 15;63(8):1853-9.

8.

Selenium modifies the metabolism and toxicity of arsenic in primary rat hepatocytes.

Styblo M, Thomas DJ.

Toxicol Appl Pharmacol. 2001 Apr 1;172(1):52-61.

PMID:
11264023
9.

Metabolism of arsenic in human liver: the role of membrane transporters.

Drobná Z, Walton FS, Paul DS, Xing W, Thomas DJ, Stýblo M.

Arch Toxicol. 2010 Jan;84(1):3-16. doi: 10.1007/s00204-009-0499-7. Epub 2009 Dec 18. Review.

PMID:
20020104
10.

Uptake of inorganic and organic derivatives of arsenic associated with induced cytotoxic and genotoxic effects in Chinese hamster ovary (CHO) cells.

Dopp E, Hartmann LM, Florea AM, von Recklinghausen U, Pieper R, Shokouhi B, Rettenmeier AW, Hirner AV, Obe G.

Toxicol Appl Pharmacol. 2004 Dec 1;201(2):156-65.

PMID:
15541755
11.

Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes.

Lin S, Del Razo LM, Styblo M, Wang C, Cullen WR, Thomas DJ.

Chem Res Toxicol. 2001 Mar;14(3):305-11.

PMID:
11258980
12.

Methylated trivalent arsenic species are genotoxic.

Mass MJ, Tennant A, Roop BC, Cullen WR, Styblo M, Thomas DJ, Kligerman AD.

Chem Res Toxicol. 2001 Apr;14(4):355-61.

PMID:
11304123
13.
14.

Toxicity of dimethylmonothioarsinic acid toward human epidermoid carcinoma A431 cells.

Naranmandura H, Ibata K, Suzuki KT.

Chem Res Toxicol. 2007 Aug;20(8):1120-5. Epub 2007 Jul 13.

PMID:
17630711
15.

Ginsenoside Rb1 stimulates glucose uptake through insulin-like signaling pathway in 3T3-L1 adipocytes.

Shang W, Yang Y, Zhou L, Jiang B, Jin H, Chen M.

J Endocrinol. 2008 Sep;198(3):561-9. doi: 10.1677/JOE-08-0104. Epub 2008 Jun 11.

16.

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response.

Xue P, Hou Y, Zhang Q, Woods CG, Yarborough K, Liu H, Sun G, Andersen ME, Pi J.

Biochem Biophys Res Commun. 2011 Apr 8;407(2):360-5. doi: 10.1016/j.bbrc.2011.03.024. Epub 2011 Mar 17.

17.

Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes.

Drobná Z, Waters SB, Walton FS, LeCluyse EL, Thomas DJ, Stýblo M.

Toxicol Appl Pharmacol. 2004 Dec 1;201(2):166-77.

PMID:
15541756
18.

Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase.

Drobná Z, Waters SB, Devesa V, Harmon AW, Thomas DJ, Stýblo M.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2):147-59.

19.

Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer cells.

Naranmandura H, Ogra Y, Iwata K, Lee J, Suzuki KT, Weinfeld M, Le XC.

Toxicol Appl Pharmacol. 2009 Jul 15;238(2):133-40. doi: 10.1016/j.taap.2009.05.006. Epub 2009 May 12.

PMID:
19442679
20.

Direct analysis and stability of methylated trivalent arsenic metabolites in cells and tissues.

Currier JM, Svoboda M, Matoušek T, Dědina J, Stýblo M.

Metallomics. 2011 Dec;3(12):1347-54. doi: 10.1039/c1mt00095k. Epub 2011 Oct 21.

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