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Items: 1 to 20 of 103

1.

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

Howard JK, Cave BJ, Oksanen LJ, Tzameli I, Bjørbaek C, Flier JS.

Nat Med. 2004 Jul;10(7):734-8. Epub 2004 Jun 27.

PMID:
15220914
2.

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity.

Mori H, Hanada R, Hanada T, Aki D, Mashima R, Nishinakamura H, Torisu T, Chien KR, Yasukawa H, Yoshimura A.

Nat Med. 2004 Jul;10(7):739-43. Epub 2004 Jun 20.

PMID:
15208705
3.

Lentiviral vector-mediated knockdown of SOCS3 in the hypothalamus protects against the development of diet-induced obesity in rats.

Liu ZJ, Bian J, Zhao YL, Zhang X, Zou N, Li D.

Diabetes Obes Metab. 2011 Oct;13(10):885-92. doi: 10.1111/j.1463-1326.2011.01419.x.

PMID:
21554522
4.

Molecular and anatomical determinants of central leptin resistance.

Münzberg H, Myers MG Jr.

Nat Neurosci. 2005 May;8(5):566-70. Review.

PMID:
15856064
5.

Modulation of central leptin sensitivity and energy balance in a rat model of diet-induced obesity.

Fam BC, Morris MJ, Hansen MJ, Kebede M, Andrikopoulos S, Proietto J, Thorburn AW.

Diabetes Obes Metab. 2007 Nov;9(6):840-52.

PMID:
17924866
6.

Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.

Reed AS, Unger EK, Olofsson LE, Piper ML, Myers MG Jr, Xu AW.

Diabetes. 2010 Apr;59(4):894-906. doi: 10.2337/db09-1024. Epub 2010 Jan 12.

7.
8.

Excessive nitric oxide attenuates leptin-mediated signal transducer and activator of transcription 3 activation.

Jang EH, Park CS, Lee SK, Pie JE, Kang JH.

Life Sci. 2007 Jan 23;80(7):609-17. Epub 2006 Oct 20.

PMID:
17097687
9.

Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.

Mori MA, Araújo RC, Reis FC, Sgai DG, Fonseca RG, Barros CC, Merino VF, Passadore M, Barbosa AM, Ferrari B, Carayon P, Castro CH, Shimuta SI, Luz J, Bascands JL, Schanstra JP, Even PC, Oliveira SM, Bader M, Pesquero JB.

Diabetes. 2008 Jun;57(6):1491-500. doi: 10.2337/db07-1508. Epub 2008 Mar 10.

10.

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.

Kievit P, Howard JK, Badman MK, Balthasar N, Coppari R, Mori H, Lee CE, Elmquist JK, Yoshimura A, Flier JS.

Cell Metab. 2006 Aug;4(2):123-32.

11.

Suppressors of cytokine signaling-1 and -3 regulate osteoclastogenesis in the presence of inflammatory cytokines.

Ohishi M, Matsumura Y, Aki D, Mashima R, Taniguchi K, Kobayashi T, Kukita T, Iwamoto Y, Yoshimura A.

J Immunol. 2005 Mar 1;174(5):3024-31.

12.

Signaling through Tyr985 of leptin receptor as an age/diet-dependent switch in the regulation of energy balance.

You J, Yu Y, Jiang L, Li W, Yu X, Gonzalez L, Yang G, Ke Z, Li W, Li C, Liu Y.

Mol Cell Biol. 2010 Apr;30(7):1650-9. doi: 10.1128/MCB.01307-09. Epub 2010 Jan 19.

13.

The role of leptin in leptin resistance and obesity.

Zhang Y, Scarpace PJ.

Physiol Behav. 2006 Jun 30;88(3):249-56. Epub 2006 Jun 16. Review.

PMID:
16782141
14.

Inactivation of Socs3 in the hypothalamus enhances the hindbrain response to endogenous satiety signals via oxytocin signaling.

Matarazzo V, Schaller F, Nédélec E, Benani A, Pénicaud L, Muscatelli F, Moyse E, Bauer S.

J Neurosci. 2012 Nov 28;32(48):17097-107. doi: 10.1523/JNEUROSCI.1669-12.2012.

15.

Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance.

Bodary PF, Shen Y, Ohman M, Bahrou KL, Vargas FB, Cudney SS, Wickenheiser KJ, Myers MG Jr, Eitzman DT.

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):70-6. Epub 2006 Nov 9.

16.
17.

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.

Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB.

Neuron. 2006 Jan 19;49(2):191-203.

18.

Attenuation of leptin and insulin signaling by SOCS proteins.

Howard JK, Flier JS.

Trends Endocrinol Metab. 2006 Nov;17(9):365-71. Epub 2006 Sep 28. Review.

PMID:
17010638
19.

Leptin signaling in the central nervous system and the periphery.

Bjørbaek C, Kahn BB.

Recent Prog Horm Res. 2004;59:305-31. Review.

PMID:
14749508
20.

Leptin receptor action and mechanisms of leptin resistance.

Münzberg H, Björnholm M, Bates SH, Myers MG Jr.

Cell Mol Life Sci. 2005 Mar;62(6):642-52. Review.

PMID:
15770417
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