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Results: 1 to 20 of 110

1.

The mGluR theory of fragile X mental retardation.

Bear MF, Huber KM, Warren ST.

Trends Neurosci. 2004 Jul;27(7):370-7. Review.

PMID:
15219735
[PubMed - indexed for MEDLINE]
2.

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.

Nosyreva ED, Huber KM.

J Neurophysiol. 2006 May;95(5):3291-5. Epub 2006 Feb 1.

PMID:
16452252
[PubMed - indexed for MEDLINE]
Free Article
3.

Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.

Niere F, Wilkerson JR, Huber KM.

J Neurosci. 2012 Apr 25;32(17):5924-36. doi: 10.1523/JNEUROSCI.4650-11.2012.

PMID:
22539853
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Altered synaptic plasticity in a mouse model of fragile X mental retardation.

Huber KM, Gallagher SM, Warren ST, Bear MF.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7746-50.

PMID:
12032354
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice.

Iliff AJ, Renoux AJ, Krans A, Usdin K, Sutton MA, Todd PK.

Hum Mol Genet. 2013 Mar 15;22(6):1180-92. doi: 10.1093/hmg/dds525. Epub 2012 Dec 18.

PMID:
23250915
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.

Hou L, Antion MD, Hu D, Spencer CM, Paylor R, Klann E.

Neuron. 2006 Aug 17;51(4):441-54.

PMID:
16908410
[PubMed - indexed for MEDLINE]
Free Article
7.

Therapeutic implications of the mGluR theory of fragile X mental retardation.

Bear MF.

Genes Brain Behav. 2005 Aug;4(6):393-8. Review.

PMID:
16098137
[PubMed - indexed for MEDLINE]
8.

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.

Todd PK, Mack KJ, Malter JS.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14374-8. Epub 2003 Nov 12.

PMID:
14614133
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses.

Antar LN, Afroz R, Dictenberg JB, Carroll RC, Bassell GJ.

J Neurosci. 2004 Mar 17;24(11):2648-55.

PMID:
15028757
[PubMed - indexed for MEDLINE]
Free Article
10.

Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis.

Auerbach BD, Bear MF.

J Neurophysiol. 2010 Aug;104(2):1047-51. doi: 10.1152/jn.00449.2010. Epub 2010 Jun 16.

PMID:
20554840
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain.

Aschrafi A, Cunningham BA, Edelman GM, Vanderklish PW.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2180-5. Epub 2005 Jan 31.

PMID:
15684045
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dysregulation of mTOR signaling in fragile X syndrome.

Sharma A, Hoeffer CA, Takayasu Y, Miyawaki T, McBride SM, Klann E, Zukin RS.

J Neurosci. 2010 Jan 13;30(2):694-702. doi: 10.1523/JNEUROSCI.3696-09.2010.

PMID:
20071534
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Fragile X mental retardation protein in plasticity and disease.

Todd PK, Malter JS.

J Neurosci Res. 2002 Dec 1;70(5):623-30. Review.

PMID:
12424729
[PubMed - indexed for MEDLINE]
14.

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.

Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. Epub 2007 Sep 19.

PMID:
17881561
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models.

Zhang J, Hou L, Klann E, Nelson DL.

J Neurophysiol. 2009 May;101(5):2572-80. doi: 10.1152/jn.90558.2008. Epub 2009 Feb 25.

PMID:
19244359
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.

Ronesi JA, Huber KM.

Sci Signal. 2008 Feb 5;1(5):pe6. doi: 10.1126/stke.15pe6. Review.

PMID:
18272470
[PubMed - indexed for MEDLINE]
17.

Protein translation in synaptic plasticity: mGluR-LTD, Fragile X.

Waung MW, Huber KM.

Curr Opin Neurobiol. 2009 Jun;19(3):319-26. doi: 10.1016/j.conb.2009.03.011. Epub 2009 May 4. Review.

PMID:
19411173
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Dual regulation of fragile X mental retardation protein by group I metabotropic glutamate receptors controls translation-dependent epileptogenesis in the hippocampus.

Zhao W, Chuang SC, Bianchi R, Wong RK.

J Neurosci. 2011 Jan 12;31(2):725-34. doi: 10.1523/JNEUROSCI.2915-10.2011.

PMID:
21228181
[PubMed - indexed for MEDLINE]
Free Article
19.

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.

Muddashetty RS, Kelić S, Gross C, Xu M, Bassell GJ.

J Neurosci. 2007 May 16;27(20):5338-48.

PMID:
17507556
[PubMed - indexed for MEDLINE]
Free Article
20.

Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation.

Volk LJ, Pfeiffer BE, Gibson JR, Huber KM.

J Neurosci. 2007 Oct 24;27(43):11624-34.

PMID:
17959805
[PubMed - indexed for MEDLINE]
Free Article

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