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Results: 1 to 20 of 203

1.

RNA interference: a new mechanism by which FMRP acts in the normal brain? What can Drosophila teach us?

Siomi H, Ishizuka A, Siomi MC.

Ment Retard Dev Disabil Res Rev. 2004;10(1):68-74. Review.

PMID:
14994291
[PubMed - indexed for MEDLINE]
2.

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

Ishizuka A, Siomi MC, Siomi H.

Genes Dev. 2002 Oct 1;16(19):2497-508.

PMID:
12368261
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A role for the Drosophila fragile X-related gene in circadian output.

Inoue S, Shimoda M, Nishinokubi I, Siomi MC, Okamura M, Nakamura A, Kobayashi S, Ishida N, Siomi H.

Curr Biol. 2002 Aug 6;12(15):1331-5.

PMID:
12176363
[PubMed - indexed for MEDLINE]
4.

The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1.

Xu K, Bogert BA, Li W, Su K, Lee A, Gao FB.

Curr Biol. 2004 Jun 22;14(12):1025-34.

PMID:
15202995
[PubMed - indexed for MEDLINE]
5.

Protein expression profiling of the drosophila fragile X mutant brain reveals up-regulation of monoamine synthesis.

Zhang YQ, Friedman DB, Wang Z, Woodruff E 3rd, Pan L, O'donnell J, Broadie K.

Mol Cell Proteomics. 2005 Mar;4(3):278-90. Epub 2005 Jan 4.

PMID:
15634690
[PubMed - indexed for MEDLINE]
Free Article
6.

Understanding fragile X syndrome: insights from retarded flies.

Gao FB.

Neuron. 2002 Jun 13;34(6):859-62. Review.

PMID:
12086633
[PubMed - indexed for MEDLINE]
7.

Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects.

Pepper AS, Beerman RW, Bhogal B, Jongens TA.

PLoS One. 2009 Oct 27;4(10):e7618. doi: 10.1371/journal.pone.0007618.

PMID:
19888420
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation.

Pan L, Zhang YQ, Woodruff E, Broadie K.

Curr Biol. 2004 Oct 26;14(20):1863-70.

PMID:
15498496
[PubMed - indexed for MEDLINE]
9.

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein.

Wan L, Dockendorff TC, Jongens TA, Dreyfuss G.

Mol Cell Biol. 2000 Nov;20(22):8536-47.

PMID:
11046149
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants.

Michel CI, Kraft R, Restifo LL.

J Neurosci. 2004 Jun 23;24(25):5798-809.

PMID:
15215302
[PubMed - indexed for MEDLINE]
Free Article
11.

Fragile X-related protein and VIG associate with the RNA interference machinery.

Caudy AA, Myers M, Hannon GJ, Hammond SM.

Genes Dev. 2002 Oct 1;16(19):2491-6.

PMID:
12368260
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria.

Yao A, Jin S, Li X, Liu Z, Ma X, Tang J, Zhang YQ.

Hum Mol Genet. 2011 Jan 1;20(1):51-63. doi: 10.1093/hmg/ddq431. Epub 2010 Oct 8.

PMID:
20935173
[PubMed - indexed for MEDLINE]
Free Article
13.

Evidence that fragile X mental retardation protein is a negative regulator of translation.

Laggerbauer B, Ostareck D, Keidel EM, Ostareck-Lederer A, Fischer U.

Hum Mol Genet. 2001 Feb 15;10(4):329-38.

PMID:
11157796
[PubMed - indexed for MEDLINE]
Free Article
14.

Novel features of dFMR1, the Drosophila orthologue of the fragile X mental retardation protein.

Schenck A, Van de Bor V, Bardoni B, Giangrande A.

Neurobiol Dis. 2002 Oct;11(1):53-63.

PMID:
12460546
[PubMed - indexed for MEDLINE]
15.

A decade of molecular studies of fragile X syndrome.

O'Donnell WT, Warren ST.

Annu Rev Neurosci. 2002;25:315-38. Epub 2002 Mar 20. Review.

PMID:
12052912
[PubMed - indexed for MEDLINE]
16.

The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain.

Reeve SP, Bassetto L, Genova GK, Kleyner Y, Leyssen M, Jackson FR, Hassan BA.

Curr Biol. 2005 Jun 21;15(12):1156-63.

PMID:
15964283
[PubMed - indexed for MEDLINE]
Free Article
17.

Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway.

Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, Nelson DL, Moses K, Warren ST.

Nat Neurosci. 2004 Feb;7(2):113-7. Epub 2004 Jan 4.

PMID:
14703574
[PubMed - indexed for MEDLINE]
18.

The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis.

Zhang YQ, Matthies HJ, Mancuso J, Andrews HK, Woodruff E 3rd, Friedman D, Broadie K.

Dev Biol. 2004 Jun 15;270(2):290-307.

PMID:
15183715
[PubMed - indexed for MEDLINE]
19.

In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.

Coffee RL Jr, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K.

Hum Mol Genet. 2012 Feb 15;21(4):900-15. doi: 10.1093/hmg/ddr527. Epub 2011 Nov 11.

PMID:
22080836
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.

Coffee RL Jr, Tessier CR, Woodruff EA 3rd, Broadie K.

Dis Model Mech. 2010 Jul-Aug;3(7-8):471-85. doi: 10.1242/dmm.004598. Epub 2010 May 4.

PMID:
20442204
[PubMed - indexed for MEDLINE]
Free PMC Article
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