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Similar articles for PubMed (Select 14966529)


pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia.

Simin K, Wu H, Lu L, Pinkel D, Albertson D, Cardiff RD, Van Dyke T.

PLoS Biol. 2004 Feb;2(2):E22. Epub 2004 Feb 17. Review.


Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo.

Knappskog S, Berge EO, Chrisanthar R, Geisler S, Staalesen V, Leirvaag B, Yndestad S, de Faveri E, Karlsen BO, Wedge DC, Akslen LA, Lilleng PK, Løkkevik E, Lundgren S, Østenstad B, Risberg T, Mjaaland I, Aas T, Lønning PE.

Mol Oncol. 2015 May 8. pii: S1574-7891(15)00096-4. doi: 10.1016/j.molonc.2015.04.008. [Epub ahead of print]


Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins.

Vilas JM, Ferreirós A, Carneiro C, Morey L, Da Silva-Álvarez S, Fernandes T, Abad M, Di Croce L, García-Caballero T, Serrano M, Rivas C, Vidal A, Collado M.

Oncotarget. 2015 Feb 20;6(5):2992-3002.


Antitumor mechanisms when pRb and p53 are genetically inactivated.

Zhu L, Lu Z, Zhao H.

Oncogene. 2014 Dec 8. doi: 10.1038/onc.2014.399. [Epub ahead of print] Review.


Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.

Piunti A, Rossi A, Cerutti A, Albert M, Jammula S, Scelfo A, Cedrone L, Fragola G, Olsson L, Koseki H, Testa G, Casola S, Helin K, d'Adda di Fagagna F, Pasini D.

Nat Commun. 2014 Apr 14;5:3649. doi: 10.1038/ncomms4649.


Skin Tumors Rb(eing) Uncovered.

Costa C, Paramio JM, Santos M.

Front Oncol. 2013 Dec 17;3:307. doi: 10.3389/fonc.2013.00307. Review.


Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues.

Song Y, Gilbert D, O'Sullivan TN, Yang C, Pan W, Fathalizadeh A, Lu L, Haines DC, Martin PL, Van Dyke T.

PLoS One. 2013 Dec 2;8(12):e80459. doi: 10.1371/journal.pone.0080459. eCollection 2013.


Animal models in retinoblastoma research.

Nair RM, Kaliki S, Vemuganti GK.

Saudi J Ophthalmol. 2013 Jul;27(3):141-6. doi: 10.1016/j.sjopt.2013.06.008.


Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation.

Manning AL, Benes C, Dyson NJ.

Oncogene. 2014 May 8;33(19):2487-94. doi: 10.1038/onc.2013.201. Epub 2013 Jun 24.


A novel tumor suppressor network in squamous malignancies.

Costa C, Santos M, Segrelles C, Dueñas M, Lara MF, Agirre X, Prosper F, García-Escudero R, Paramio JM.

Sci Rep. 2012;2:828. doi: 10.1038/srep00828. Epub 2012 Nov 9.


IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.

Zuo S, Liu C, Wang J, Wang F, Xu W, Cui S, Yuan L, Chen X, Fan W, Cui M, Song G.

J Cancer Res Clin Oncol. 2012 Jun;138(6):1045-55. doi: 10.1007/s00432-012-1153-y. Epub 2012 Mar 6.


ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein.

Boulay PL, Schlienger S, Lewis-Saravalli S, Vitale N, Ferbeyre G, Claing A.

Oncogene. 2011 Sep 8;30(36):3846-61. doi: 10.1038/onc.2011.100. Epub 2011 Apr 11.


Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers.

Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE.

Mol Cancer. 2010 Jul 1;9:173. doi: 10.1186/1476-4598-9-173.


Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response.

Weiss MB, Vitolo MI, Mohseni M, Rosen DM, Denmeade SR, Park BH, Weber DJ, Bachman KE.

Oncogene. 2010 Aug 19;29(33):4715-24. doi: 10.1038/onc.2010.220. Epub 2010 Jun 21.


Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.

He F, Mo L, Zheng XY, Hu C, Lepor H, Lee EY, Sun TT, Wu XR.

Cancer Res. 2009 Dec 15;69(24):9413-21. doi: 10.1158/0008-5472.CAN-09-2158. Epub .


Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.

Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP.

Am J Pathol. 2009 Mar;174(3):746-61. doi: 10.2353/ajpath.2009.080658.


A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression.

Karantza-Wadsworth V, White E.

Methods Enzymol. 2008;446:61-76. doi: 10.1016/S0076-6879(08)01604-2.


Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

Arima Y, Inoue Y, Shibata T, Hayashi H, Nagano O, Saya H, Taya Y.

Cancer Res. 2008 Jul 1;68(13):5104-12. doi: 10.1158/0008-5472.CAN-07-5680.


Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage.

Santos M, Ruiz S, Lara MF, Segrelles C, Moral M, Martínez-Cruz AB, Ballestín C, Lorz C, García-Escudero R, Paramio JM.

Mol Carcinog. 2008 Nov;47(11):815-21. doi: 10.1002/mc.20426.


Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis.

Lara MF, García-Escudero R, Ruiz S, Santos M, Moral M, Martínez-Cruz AB, Segrelles C, Lorz C, Paramio JM.

Mol Carcinog. 2008 Mar;47(3):209-21.

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