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Similar articles for PubMed (Select 14752011)


Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.

Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, Kulozik AE.

Mol Cell. 2005 Oct 7;20(1):65-75.


Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S.

Genes Dev. 2006 Feb 1;20(3):355-67.


New insights into the formation of active nonsense-mediated decay complexes.

Singh G, Lykke-Andersen J.

Trends Biochem Sci. 2003 Sep;28(9):464-6. Review.


NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.

Chamieh H, Ballut L, Bonneau F, Le Hir H.

Nat Struct Mol Biol. 2008 Jan;15(1):85-93. Epub 2007 Dec 9.


PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

Diem MD, Chan CC, Younis I, Dreyfuss G.

Nat Struct Mol Biol. 2007 Dec;14(12):1173-9. Epub 2007 Nov 18.


Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay.

Singh KK, Wachsmuth L, Kulozik AE, Gehring NH.

RNA Biol. 2013 Aug;10(8):1291-8. doi: 10.4161/rna.25827. Epub 2013 Jul 23.


Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B.

Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27.


Exon junction complex enhances translation of spliced mRNAs at multiple steps.

Lee HC, Choe J, Chi SG, Kim YK.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):334-40. doi: 10.1016/j.bbrc.2009.04.123. Epub 2009 May 3.


Structure of the Y14-Magoh core of the exon junction complex.

Lau CK, Diem MD, Dreyfuss G, Van Duyne GD.

Curr Biol. 2003 May 27;13(11):933-41.


eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.

Shibuya T, Tange TØ, Sonenberg N, Moore MJ.

Nat Struct Mol Biol. 2004 Apr;11(4):346-51. Epub 2004 Mar 21.


A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay.

Ferraiuolo MA, Lee CS, Ler LW, Hsu JL, Costa-Mattioli M, Luo MJ, Reed R, Sonenberg N.

Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4118-23. Epub 2004 Mar 15.


Disassembly of exon junction complexes by PYM.

Gehring NH, Lamprinaki S, Kulozik AE, Hentze MW.

Cell. 2009 May 1;137(3):536-48. doi: 10.1016/j.cell.2009.02.042.


Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.

Ivanov PV, Gehring NH, Kunz JB, Hentze MW, Kulozik AE.

EMBO J. 2008 Mar 5;27(5):736-47. doi: 10.1038/emboj.2008.17. Epub 2008 Feb 7.


Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module.

Degot S, Le Hir H, Alpy F, Kedinger V, Stoll I, Wendling C, Seraphin B, Rio MC, Tomasetto C.

J Biol Chem. 2004 Aug 6;279(32):33702-15. Epub 2004 May 27.


eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR.

Choe J, Ryu I, Park OH, Park J, Cho H, Yoo JS, Chi SW, Kim MK, Song HK, Kim YK.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4577-86. doi: 10.1073/pnas.1409695111. Epub 2014 Oct 13.


A new function for nonsense-mediated mRNA-decay factors.

Wilkinson MF.

Trends Genet. 2005 Mar;21(3):143-8. Review.


The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.

Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE.

PLoS Biol. 2009 May 26;7(5):e1000120. doi: 10.1371/journal.pbio.1000120. Epub 2009 May 26.


Y14 and hUpf3b form an NMD-activating complex.

Gehring NH, Neu-Yilik G, Schell T, Hentze MW, Kulozik AE.

Mol Cell. 2003 Apr;11(4):939-49.


Phosphorylation of Y14 modulates its interaction with proteins involved in mRNA metabolism and influences its methylation.

Hsu IaW, Hsu M, Li C, Chuang TW, Lin RI, Tarn WY.

J Biol Chem. 2005 Oct 14;280(41):34507-12. Epub 2005 Aug 12.

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