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Results: 1 to 20 of 313

1.

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

Cancer Res. 2003 Dec 15;63(24):8586-91.

PMID:
14695167
[PubMed - indexed for MEDLINE]
Free Article
2.

NFBD1/Mdc1 mediates ATR-dependent DNA damage response.

Peng A, Chen PL.

Cancer Res. 2005 Feb 15;65(4):1158-63.

PMID:
15734998
[PubMed - indexed for MEDLINE]
Free Article
3.

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

Wilson KA, Stern DF.

Cell Cycle. 2008 Nov 15;7(22):3584-94. Epub 2008 Nov 29.

PMID:
19001859
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.

Peng A, Chen PL.

J Biol Chem. 2003 Mar 14;278(11):8873-6. Epub 2003 Jan 24.

PMID:
12551934
[PubMed - indexed for MEDLINE]
Free Article
5.

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.

Bekker-Jensen S, Lukas C, Melander F, Bartek J, Lukas J.

J Cell Biol. 2005 Jul 18;170(2):201-11. Epub 2005 Jul 11.

PMID:
16009723
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

So S, Davis AJ, Chen DJ.

J Cell Biol. 2009 Dec 28;187(7):977-90. doi: 10.1083/jcb.200906064. Epub 2009 Dec 21. Erratum in: J Cell Biol. 2010 Feb 8;188(3):443.

PMID:
20026654
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.

PMID:
16905549
[PubMed - indexed for MEDLINE]
Free Article
8.

NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors.

Xu X, Stern DF.

FASEB J. 2003 Oct;17(13):1842-8.

PMID:
14519663
[PubMed - indexed for MEDLINE]
Free Article
9.

53BP1, an activator of ATM in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):945-52.

PMID:
15279780
[PubMed - indexed for MEDLINE]
10.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22.

PMID:
15784679
[PubMed - indexed for MEDLINE]
Free Article
11.

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

Shibata A, Barton O, Noon AT, Dahm K, Deckbar D, Goodarzi AA, Löbrich M, Jeggo PA.

Mol Cell Biol. 2010 Jul;30(13):3371-83. doi: 10.1128/MCB.01644-09. Epub 2010 Apr 26.

PMID:
20421415
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

MDC1 is required for the intra-S-phase DNA damage checkpoint.

Goldberg M, Stucki M, Falck J, D'Amours D, Rahman D, Pappin D, Bartek J, Jackson SP.

Nature. 2003 Feb 27;421(6926):952-6.

PMID:
12607003
[PubMed - indexed for MEDLINE]
13.

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.

Lukas C, Melander F, Stucki M, Falck J, Bekker-Jensen S, Goldberg M, Lerenthal Y, Jackson SP, Bartek J, Lukas J.

EMBO J. 2004 Jul 7;23(13):2674-83. Epub 2004 Jun 17.

PMID:
15201865
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.

Schultz LB, Chehab NH, Malikzay A, Halazonetis TD.

J Cell Biol. 2000 Dec 25;151(7):1381-90.

PMID:
11134068
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control.

Lou Z, Chini CC, Minter-Dykhouse K, Chen J.

J Biol Chem. 2003 Apr 18;278(16):13599-602. Epub 2003 Feb 27.

PMID:
12611903
[PubMed - indexed for MEDLINE]
Free Article
16.

Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation.

Jowsey PA, Doherty AJ, Rouse J.

J Biol Chem. 2004 Dec 31;279(53):55562-9. Epub 2004 Sep 27.

PMID:
15456759
[PubMed - indexed for MEDLINE]
Free Article
17.

Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.

Shirata N, Kudoh A, Daikoku T, Tatsumi Y, Fujita M, Kiyono T, Sugaya Y, Isomura H, Ishizaki K, Tsurumi T.

J Biol Chem. 2005 Aug 26;280(34):30336-41. Epub 2005 Jun 17.

PMID:
15964848
[PubMed - indexed for MEDLINE]
Free Article
18.

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.

Krause DR, Jonnalagadda JC, Gatei MH, Sillje HH, Zhou BB, Nigg EA, Khanna K.

Oncogene. 2003 Sep 4;22(38):5927-37.

PMID:
12955071
[PubMed - indexed for MEDLINE]
19.

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.

Noon AT, Shibata A, Rief N, Löbrich M, Stewart GS, Jeggo PA, Goodarzi AA.

Nat Cell Biol. 2010 Feb;12(2):177-84. doi: 10.1038/ncb2017. Epub 2010 Jan 17.

PMID:
20081839
[PubMed - indexed for MEDLINE]
20.

RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

Sakasai R, Tibbetts R.

J Biol Chem. 2008 May 16;283(20):13549-55. doi: 10.1074/jbc.M710197200. Epub 2008 Mar 12.

PMID:
18337245
[PubMed - indexed for MEDLINE]
Free Article

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