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Results: 1 to 20 of 143

1.

Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta.

Greene MW, Morrice N, Garofalo RS, Roth RA.

Biochem J. 2004 Feb 15;378(Pt 1):105-16.

PMID:
14583092
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).

Kellerer M, Mushack J, Seffer E, Mischak H, Ullrich A, Häring HU.

Diabetologia. 1998 Jul;41(7):833-8.

PMID:
9686926
[PubMed - indexed for MEDLINE]
3.

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

De Fea K, Roth RA.

Biochemistry. 1997 Oct 21;36(42):12939-47.

PMID:
9335553
[PubMed - indexed for MEDLINE]
4.

In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.

Sommerfeld MR, Metzger S, Stosik M, Tennagels N, Eckel J.

Biochemistry. 2004 May 18;43(19):5888-901.

PMID:
15134463
[PubMed - indexed for MEDLINE]
5.

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1.

Moeschel K, Beck A, Weigert C, Lammers R, Kalbacher H, Voelter W, Schleicher ED, Häring HU, Lehmann R.

J Biol Chem. 2004 Jun 11;279(24):25157-63. Epub 2004 Apr 5.

PMID:
15069075
[PubMed - indexed for MEDLINE]
Free Article
6.

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase.

De Fea K, Roth RA.

J Biol Chem. 1997 Dec 12;272(50):31400-6.

PMID:
9395471
[PubMed - indexed for MEDLINE]
Free Article
7.
8.

PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function.

Greene MW, Ruhoff MS, Roth RA, Kim JA, Quon MJ, Krause JA.

Biochem Biophys Res Commun. 2006 Oct 27;349(3):976-86. Epub 2006 Sep 5.

PMID:
16970908
[PubMed - indexed for MEDLINE]
9.

Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.

Liberman Z, Eldar-Finkelman H.

J Biol Chem. 2005 Feb 11;280(6):4422-8. Epub 2004 Nov 30.

PMID:
15574412
[PubMed - indexed for MEDLINE]
Free Article
10.

Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling.

Rosenzweig T, Braiman L, Bak A, Alt A, Kuroki T, Sampson SR.

Diabetes. 2002 Jun;51(6):1921-30.

PMID:
12031982
[PubMed - indexed for MEDLINE]
Free Article
11.

Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.

Müssig K, Staiger H, Fiedler H, Moeschel K, Beck A, Kellerer M, Häring HU.

J Biol Chem. 2005 Sep 23;280(38):32693-9. Epub 2005 Jul 29.

PMID:
16055440
[PubMed - indexed for MEDLINE]
Free Article
12.

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta.

Denning MF, Dlugosz AA, Threadgill DW, Magnuson T, Yuspa SH.

J Biol Chem. 1996 Mar 8;271(10):5325-31.

PMID:
8621384
[PubMed - indexed for MEDLINE]
Free Article
13.

Expression of dominant negative mutant SHPTP2 attenuates phosphatidylinositol 3'-kinase activity via modulation of phosphorylation of insulin receptor substrate-1.

Ugi S, Maegawa H, Kashiwagi A, Adachi M, Olefsky JM, Kikkawa R.

J Biol Chem. 1996 May 24;271(21):12595-602.

PMID:
8647870
[PubMed - indexed for MEDLINE]
Free Article
14.

Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.

Harada S, Smith RM, Smith JA, White MF, Jarett L.

J Biol Chem. 1996 Nov 22;271(47):30222-6. Erratum in: J Biol Chem 1997 Jan 31;272(5):3124.

PMID:
8939974
[PubMed - indexed for MEDLINE]
Free Article
16.

PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.

Mingo-Sion AM, Ferguson HA, Koller E, Reyland ME, Van Den Berg CL.

Breast Cancer Res Treat. 2005 Jun;91(3):259-69.

PMID:
15952059
[PubMed - indexed for MEDLINE]
17.

Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells.

Waraich RS, Weigert C, Kalbacher H, Hennige AM, Lutz SZ, Häring HU, Schleicher ED, Voelter W, Lehmann R.

J Biol Chem. 2008 Apr 25;283(17):11226-33. doi: 10.1074/jbc.M708588200. Epub 2008 Feb 19.

PMID:
18285345
[PubMed - indexed for MEDLINE]
Free Article
18.

Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.

Greene MW, Sakaue H, Wang L, Alessi DR, Roth RA.

J Biol Chem. 2003 Mar 7;278(10):8199-211. Epub 2003 Jan 1.

PMID:
12510059
[PubMed - indexed for MEDLINE]
Free Article
19.

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.

Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M.

Mol Cell Biol. 1994 Oct;14(10):6674-82.

PMID:
7935386
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1.

Yonezawa K, Ueda H, Hara K, Nishida K, Ando A, Chavanieu A, Matsuba H, Shii K, Yokono K, Fukui Y, et al.

J Biol Chem. 1992 Dec 25;267(36):25958-65.

PMID:
1334490
[PubMed - indexed for MEDLINE]
Free Article

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