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Results: 1 to 20 of 343

1.

Ricin. Mechanisms of cytotoxicity.

Lord MJ, Jolliffe NA, Marsden CJ, Pateman CS, Smith DC, Spooner RA, Watson PD, Roberts LM.

Toxicol Rev. 2003;22(1):53-64. Review.

PMID:
14579547
[PubMed - indexed for MEDLINE]
2.

Cytotoxic ribosome-inactivating lectins from plants.

Hartley MR, Lord JM.

Biochim Biophys Acta. 2004 Sep 1;1701(1-2):1-14. Review.

PMID:
15450171
[PubMed - indexed for MEDLINE]
Free Article
3.

Ricin: the endoplasmic reticulum connection.

Roberts LM, Smith DC.

Toxicon. 2004 Oct;44(5):469-72. Review.

PMID:
15450920
[PubMed - indexed for MEDLINE]
4.

The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol.

Deeks ED, Cook JP, Day PJ, Smith DC, Roberts LM, Lord JM.

Biochemistry. 2002 Mar 12;41(10):3405-13.

PMID:
11876649
[PubMed - indexed for MEDLINE]
5.

The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol.

Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K.

Biochem J. 2014 Feb 1;457(3):485-96. doi: 10.1042/BJ20130155.

PMID:
24200403
[PubMed - indexed for MEDLINE]
6.

Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells.

Vago R, Marsden CJ, Lord JM, Ippoliti R, Flavell DJ, Flavell SU, Ceriotti A, Fabbrini MS.

FEBS J. 2005 Oct;272(19):4983-95.

PMID:
16176271
[PubMed - indexed for MEDLINE]
Free Article
7.

Binding of ricin A-chain to negatively charged phospholipid vesicles leads to protein structural changes and destabilizes the lipid bilayer.

Day PJ, Pinheiro TJ, Roberts LM, Lord JM.

Biochemistry. 2002 Feb 26;41(8):2836-43.

PMID:
11851431
[PubMed - indexed for MEDLINE]
8.

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation.

Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M.

Biochem J. 2011 Jun 1;436(2):371-85. doi: 10.1042/BJ20101493.

PMID:
21388347
[PubMed - indexed for MEDLINE]
Free Article
9.

Endoplasmic reticulum-associated degradation of ricin A chain has unique and plant-specific features.

Di Cola A, Frigerio L, Lord JM, Roberts LM, Ceriotti A.

Plant Physiol. 2005 Jan;137(1):287-96. Epub 2004 Dec 23.

PMID:
15618412
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ricin A chain reaches the endoplasmic reticulum after endocytosis.

Liu Q, Zhan J, Chen X, Zheng S.

Biochem Biophys Res Commun. 2006 May 12;343(3):857-63. Epub 2006 Mar 20.

PMID:
16564502
[PubMed - indexed for MEDLINE]
11.

Endocytosis and intracellular transport of ricin: recent discoveries.

Sandvig K, van Deurs B.

FEBS Lett. 1999 Jun 4;452(1-2):67-70. Review.

PMID:
10376680
[PubMed - indexed for MEDLINE]
Free Article
12.

Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells.

Wales R, Roberts LM, Lord JM.

J Biol Chem. 1993 Nov 15;268(32):23986-90.

PMID:
8226941
[PubMed - indexed for MEDLINE]
Free Article
13.

Assessment of ligand effects in intracellular trafficking of ricin A chain using anti-ricin hybridomas.

Kornfeld SB, Leonard JE, Mullen MD, Taetle R.

Cancer Res. 1991 Mar 15;51(6):1689-93.

PMID:
1998959
[PubMed - indexed for MEDLINE]
Free Article
14.

Retrograde transport of ricin.

Wesche J.

Int J Med Microbiol. 2002 Feb;291(6-7):517-21. Review.

PMID:
11890552
[PubMed - indexed for MEDLINE]
15.

Differences in cytotoxicity of native and engineered RIPs can be used to assess their ability to reach the cytoplasm.

Svinth M, Steighardt J, Hernandez R, Suh JK, Kelly C, Day P, Lord M, Girbes T, Robertus JD.

Biochem Biophys Res Commun. 1998 Aug 28;249(3):637-42.

PMID:
9731188
[PubMed - indexed for MEDLINE]
16.

Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol.

Wesche J, Rapak A, Olsnes S.

J Biol Chem. 1999 Nov 26;274(48):34443-9.

PMID:
10567425
[PubMed - indexed for MEDLINE]
Free Article
17.

Ribosome-mediated folding of partially unfolded ricin A-chain.

Argent RH, Parrott AM, Day PJ, Roberts LM, Stockley PG, Lord JM, Radford SE.

J Biol Chem. 2000 Mar 31;275(13):9263-9.

PMID:
10734065
[PubMed - indexed for MEDLINE]
Free Article
18.

Ricin A chain can transport unfolded dihydrofolate reductase into the cytosol.

Beaumelle B, Taupiac MP, Lord JM, Roberts LM.

J Biol Chem. 1997 Aug 29;272(35):22097-102.

PMID:
9268352
[PubMed - indexed for MEDLINE]
Free Article
19.

Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: co-opting basic mechanisms of endoplasmic reticulum-associated degradation.

Lord JM, Roberts LM, Lencer WI.

Curr Top Microbiol Immunol. 2005;300:149-68. Review.

PMID:
16573240
[PubMed - indexed for MEDLINE]
20.

Ricin toxin contains at least three galactose-binding sites located in B chain subdomains 1 alpha, 1 beta, and 2 gamma.

Frankel AE, Burbage C, Fu T, Tagge E, Chandler J, Willingham MC.

Biochemistry. 1996 Nov 26;35(47):14749-56.

PMID:
8942636
[PubMed - indexed for MEDLINE]

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