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Results: 1 to 20 of 157

1.

Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.

Uemura K, Kitagawa N, Kohno R, Kuzuya A, Kageyama T, Chonabayashi K, Shibasaki H, Shimohama S.

J Neurosci Res. 2003 Oct 15;74(2):184-91.

PMID:
14515347
[PubMed - indexed for MEDLINE]
2.

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex.

Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich VL Jr, Robakis NK.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2381-6.

PMID:
11226248
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion.

Singh N, Talalayeva Y, Tsiper M, Romanov V, Dranovsky A, Colflesh D, Rudamen G, Vitek MP, Shen J, Yang X, Goldgaber D, Schwarzman AL.

Exp Cell Res. 2001 Feb 1;263(1):1-13.

PMID:
11161700
[PubMed - indexed for MEDLINE]
4.

Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.

Kang DE, Soriano S, Frosch MP, Collins T, Naruse S, Sisodia SS, Leibowitz G, Levine F, Koo EH.

J Neurosci. 1999 Jun 1;19(11):4229-37.

PMID:
10341227
[PubMed - indexed for MEDLINE]
Free Article
5.

The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations.

Cedazo-Minguez A, Popescu BO, Ankarcrona M, Nishimura T, Cowburn RF.

J Biol Chem. 2002 Sep 27;277(39):36646-55. Epub 2002 Jul 16.

PMID:
12121968
[PubMed - indexed for MEDLINE]
Free Article
6.
7.

Protein trafficking and Alzheimer's disease.

Uemura K, Kuzuya A, Shimohama S.

Curr Alzheimer Res. 2004 Feb;1(1):1-10. Review.

PMID:
15975080
[PubMed - indexed for MEDLINE]
8.

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts.

Georgakopoulos A, Marambaud P, Efthimiopoulos S, Shioi J, Cui W, Li HC, Schütte M, Gordon R, Holstein GR, Martinelli G, Mehta P, Friedrich VL Jr, Robakis NK.

Mol Cell. 1999 Dec;4(6):893-902.

PMID:
10635315
[PubMed - indexed for MEDLINE]
Free Article
9.

Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.

Uemura K, Kuzuya A, Aoyagi N, Ando K, Shimozono Y, Ninomiya H, Shimohama S, Kinoshita A.

Neuroscience. 2007 Mar 2;145(1):5-10. Epub 2007 Jan 25.

PMID:
17257767
[PubMed - indexed for MEDLINE]
10.

The role of beta-catenin stability in mutant PS1-associated apoptosis.

Weihl CC, Miller RJ, Roos RP.

Neuroreport. 1999 Aug 20;10(12):2527-32.

PMID:
10574364
[PubMed - indexed for MEDLINE]
11.

Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein.

Hamano T, Mutoh T, Tabira T, Araki W, Kuriyama M, Mihara T, Yano S, Yamamoto H.

Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):70-6. Epub 2005 Mar 19.

PMID:
15950763
[PubMed - indexed for MEDLINE]
12.

Assembly of the N-cadherin complex during synapse formation involves uncoupling of p120-catenin and association with presenilin 1.

Rubio ME, Curcio C, Chauvet N, Brusés JL.

Mol Cell Neurosci. 2005 Sep;30(1):118-30. Erratum in: Mol Cell Neurosci. 2005 Dec;30(4):559. Corrected and republished in: Mol Cell Neurosci. 2005 Dec;30(4):611-23.

PMID:
16046145
[PubMed - indexed for MEDLINE]
13.

Assembly of the N-cadherin complex during synapse formation involves uncoupling of p120-catenin and association with presenilin 1.

Rubio ME, Curcio C, Chauvet N, Brusés JL.

Mol Cell Neurosci. 2005 Dec;30(4):611-23.

PMID:
16456928
[PubMed - indexed for MEDLINE]
14.

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.

Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK.

Cell. 2003 Sep 5;114(5):635-45.

PMID:
13678586
[PubMed - indexed for MEDLINE]
Free Article
15.

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G.

Nat Cell Biol. 2000 Dec;2(12):863-70.

PMID:
11146649
[PubMed - indexed for MEDLINE]
16.

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.

Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.

Nat Cell Biol. 1999 Dec;1(8):479-85.

PMID:
10587643
[PubMed - indexed for MEDLINE]
17.

Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.

Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.

J Neurosci Res. 2002 Aug 15;69(4):530-9.

PMID:
12210846
[PubMed - indexed for MEDLINE]
18.

Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.

Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H.

J Biol Chem. 2003 Jan 31;278(5):3446-54. Epub 2002 Nov 14.

PMID:
12435726
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.

Culvenor JG, Maher F, Evin G, Malchiodi-Albedi F, Cappai R, Underwood JR, Davis JB, Karran EH, Roberts GW, Beyreuther K, Masters CL.

J Neurosci Res. 1997 Sep 15;49(6):719-31.

PMID:
9335259
[PubMed - indexed for MEDLINE]

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