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Results: 1 to 20 of 104

1.

Immunophilin-sensitive protein phosphatase action in cell signaling pathways.

Schreiber SL.

Cell. 1992 Aug 7;70(3):365-8. Review. No abstract available.

PMID:
1379518
[PubMed - indexed for MEDLINE]
2.

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes.

Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, Schreiber SL.

Cell. 1991 Aug 23;66(4):807-15.

PMID:
1715244
[PubMed - indexed for MEDLINE]
3.

Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.

Bierer BE.

Chem Immunol. 1994;59:128-55. No abstract available.

PMID:
7524531
[PubMed - indexed for MEDLINE]
4.

Lessons from molecular matchmakers.

Teague S.

Nat Struct Biol. 1995 May;2(5):360-1. No abstract available.

PMID:
7545076
[PubMed - indexed for MEDLINE]
5.

Molecular analysis of the interaction of calcineurin with drug-immunophilin complexes.

Clipstone NA, Fiorentino DF, Crabtree GR.

J Biol Chem. 1994 Oct 21;269(42):26431-7.

PMID:
7523407
[PubMed - indexed for MEDLINE]
Free Article
6.

Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.

Cardenas ME, Hemenway C, Muir RS, Ye R, Fiorentino D, Heitman J.

EMBO J. 1994 Dec 15;13(24):5944-57.

PMID:
7529175
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs.

McCaffrey PG, Perrino BA, Soderling TR, Rao A.

J Biol Chem. 1993 Feb 15;268(5):3747-52.

PMID:
7679116
[PubMed - indexed for MEDLINE]
Free Article
8.

The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin.

Dawson TM, Steiner JP, Lyons WE, Fotuhi M, Blue M, Snyder SH.

Neuroscience. 1994 Sep;62(2):569-80.

PMID:
7530348
[PubMed - indexed for MEDLINE]
9.

Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin.

Bell A, Wernli B, Franklin RM.

Biochem Pharmacol. 1994 Aug 3;48(3):495-503.

PMID:
7520696
[PubMed - indexed for MEDLINE]
10.

Inhibition of T-cell signaling pathways by immunophilin drug complexes: are side effects inherent to immunosuppressive properties?

Schreier MH, Baumann G, Zenke G.

Transplant Proc. 1993 Feb;25(1 Pt 1):502-7. Review. No abstract available.

PMID:
7679818
[PubMed - indexed for MEDLINE]
11.

Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.

Cardenas ME, Muir RS, Breuder T, Heitman J.

EMBO J. 1995 Jun 15;14(12):2772-83.

PMID:
7540976
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex.

Wiederrecht G, Hung S, Chan HK, Marcy A, Martin M, Calaycay J, Boulton D, Sigal N, Kincaid RL, Siekierka JJ.

J Biol Chem. 1992 Oct 25;267(30):21753-60.

PMID:
1383226
[PubMed - indexed for MEDLINE]
Free Article
13.

Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins.

Ryffel B.

Biochem Pharmacol. 1993 Jul 6;46(1):1-12. Review. No abstract available.

PMID:
8394072
[PubMed - indexed for MEDLINE]
14.

Demonstration of ternary immunophilin-calcineurin complexes with the immunosuppressants cyclosporin and macrolide FK506.

Woerly G, Weber E, Ryffel B.

Biochem Pharmacol. 1994 Apr 20;47(8):1435-43.

PMID:
7514409
[PubMed - indexed for MEDLINE]
15.

The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation.

Milan D, Griffith J, Su M, Price ER, McKeon F.

Cell. 1994 Nov 4;79(3):437-47.

PMID:
7525078
[PubMed - indexed for MEDLINE]
16.

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location.

Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR.

Mol Cell Biol. 1993 Aug;13(8):4760-9.

PMID:
7687744
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cyclosporin A, FK506 and rapamycin: more than just immunosuppression.

Kunz J, Hall MN.

Trends Biochem Sci. 1993 Sep;18(9):334-8. Review.

PMID:
7694398
[PubMed - indexed for MEDLINE]
18.

Structure-based design of a cyclophilin-calcineurin bridging ligand.

Alberg DG, Schreiber SL.

Science. 1993 Oct 8;262(5131):248-50.

PMID:
8211144
[PubMed - indexed for MEDLINE]
19.

Binding of active cyclosporins to cyclophilin A and B, complex formation with calcineurin A.

Ryffel B, Woerly G, Murray M, Eugster HP, Car B.

Biochem Biophys Res Commun. 1993 Aug 16;194(3):1074-83.

PMID:
8394698
[PubMed - indexed for MEDLINE]
20.

When worlds collide: immunosuppressants meet protein phosphatases.

McKeon F.

Cell. 1991 Sep 6;66(5):823-6. Review. No abstract available.

PMID:
1716181
[PubMed - indexed for MEDLINE]

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