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Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.

Chow HH, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS.

Clin Cancer Res. 2003 Aug 15;9(9):3312-9.


Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E.

Chow HH, Cai Y, Alberts DS, Hakim I, Dorr R, Shahi F, Crowell JA, Yang CS, Hara Y.

Cancer Epidemiol Biomarkers Prev. 2001 Jan;10(1):53-8.


Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.

Chow HH, Hakim IA, Vining DR, Crowell JA, Ranger-Moore J, Chew WM, Celaya CA, Rodney SR, Hara Y, Alberts DS.

Clin Cancer Res. 2005 Jun 15;11(12):4627-33.


Modulation of human glutathione s-transferases by polyphenon e intervention.

Chow HH, Hakim IA, Vining DR, Crowell JA, Tome ME, Ranger-Moore J, Cordova CA, Mikhael DM, Briehl MM, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1662-6.


Effects of repeated green tea catechin administration on human cytochrome P450 activity.

Chow HH, Hakim IA, Vining DR, Crowell JA, Cordova CA, Chew WM, Xu MJ, Hsu CH, Ranger-Moore J, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2473-6.


Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.

Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S, Yang CS.

Cancer Epidemiol Biomarkers Prev. 2002 Oct;11(10 Pt 1):1025-32.


The relation between single/double or repeated tea catechin ingestions and plasma antioxidant activity in humans.

Kimura M, Umegaki K, Kasuya Y, Sugisawa A, Higuchi M.

Eur J Clin Nutr. 2002 Dec;56(12):1186-93.


Cutaneous photoprotection from ultraviolet injury by green tea polyphenols.

Elmets CA, Singh D, Tubesing K, Matsui M, Katiyar S, Mukhtar H.

J Am Acad Dermatol. 2001 Mar;44(3):425-32.


Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo.

Thangapazham RL, Singh AK, Sharma A, Warren J, Gaddipati JP, Maheshwari RK.

Cancer Lett. 2007 Jan 8;245(1-2):232-41. Epub 2006 Mar 6.


Preventive effects of polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols.

Lubet RA, Yang CS, Lee MJ, Hara Y, Kapetanovic IM, Crowell JA, Steele VE, Juliana MM, Grubbs CJ.

Mol Cancer Ther. 2007 Jul;6(7):2022-8.


Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions.

Ahn WS, Yoo J, Huh SW, Kim CK, Lee JM, Namkoong SE, Bae SM, Lee IP.

Eur J Cancer Prev. 2003 Oct;12(5):383-90.


Chitosan green tea polyphenol complex as a released control compound for wound healing.

Qin Y, Wang HW, Karuppanapandian T, Kim W.

Chin J Traumatol. 2010 Apr 1;13(2):91-5.


The green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.

Morley N, Clifford T, Salter L, Campbell S, Gould D, Curnow A.

Photodermatol Photoimmunol Photomed. 2005 Feb;21(1):15-22.


Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E).

Fu H, He J, Mei F, Zhang Q, Hara Y, Ryota S, Lubet RA, Chen R, Chen DR, You M.

Cancer Prev Res (Phila). 2009 Jun;2(6):531-7. doi: 10.1158/1940-6207.CAPR-08-0185. Epub 2009 May 26.


Absorption, distribution, elimination of tea polyphenols in rats.

Chen L, Lee MJ, Li H, Yang CS.

Drug Metab Dispos. 1997 Sep;25(9):1045-50.


Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans.

Aoki F, Nakagawa K, Kitano M, Ikematsu H, Nakamura K, Yokota S, Tominaga Y, Arai N, Mae T.

J Am Coll Nutr. 2007 Jun;26(3):209-18.

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