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Items: 1 to 20 of 188

1.

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.

Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR.

J Clin Invest. 2003 Aug;112(4):608-18.

2.

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, Nicol CJ, Vinson C, Gonzalez FJ, Reitman ML.

J Biol Chem. 2003 Sep 5;278(36):34268-76. Epub 2003 Jun 11.

3.

Muscle-specific Pparg deletion causes insulin resistance.

Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J.

Nat Med. 2003 Dec;9(12):1491-7. Epub 2003 Nov 16.

PMID:
14625542
4.

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.

5.

Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding.

Miles PD, Barak Y, Evans RM, Olefsky JM.

Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E618-26.

6.

Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action.

Zierath JR, Ryder JW, Doebber T, Woods J, Wu M, Ventre J, Li Z, McCrary C, Berger J, Zhang B, Moller DE.

Endocrinology. 1998 Dec;139(12):5034-41.

PMID:
9832442
7.

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle.

He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15712-7. Epub 2003 Dec 5.

8.

[PPARgamma and insulin resistance].

Girard J.

Ann Endocrinol (Paris). 2002 Apr;63(2 Pt 2):1S19-22. Review. French.

PMID:
12037503
9.

[Mechanisms of action of thiazolidinediones].

Girard J.

Diabetes Metab. 2001 Apr;27(2 Pt 2):271-8. Review. French.

10.

Troglitazone action is independent of adipose tissue.

Burant CF, Sreenan S, Hirano K, Tai TA, Lohmiller J, Lukens J, Davidson NO, Ross S, Graves RA.

J Clin Invest. 1997 Dec 1;100(11):2900-8.

11.

Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats.

Kramer D, Shapiro R, Adler A, Bush E, Rondinone CM.

Metabolism. 2001 Nov;50(11):1294-300.

PMID:
11699047
12.

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones.

Chao L, Marcus-Samuels B, Mason MM, Moitra J, Vinson C, Arioglu E, Gavrilova O, Reitman ML.

J Clin Invest. 2000 Nov;106(10):1221-8.

13.

Triglycerides, fatty acids and insulin resistance--hyperinsulinemia.

Kraegen EW, Cooney GJ, Ye J, Thompson AL.

Exp Clin Endocrinol Diabetes. 2001;109(4):S516-26. Review.

PMID:
11453039
14.

[Thiazolidinediones in type 2 diabetes. Role of peroxisome proliferator-activated receptor gamma (PPARgamma)].

Dubois M, Vantyghem MC, Schoonjans K, Pattou F.

Ann Endocrinol (Paris). 2002 Dec;63(6 Pt 1):511-23. Review. French.

PMID:
12527853
16.

Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.

Shen Q, Cline GW, Shulman GI, Leibowitz MD, Davies PJ.

J Biol Chem. 2004 May 7;279(19):19721-31. Epub 2004 Mar 2.

17.

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.

Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, Ide T, Kubota N, Terauchi Y, Tobe K, Miki H, Tsuchida A, Akanuma Y, Nagai R, Kimura S, Kadowaki T.

J Biol Chem. 2001 Nov 2;276(44):41245-54. Epub 2001 Aug 31.

18.

PPARgamma-mediated insulin sensitization: the importance of fat versus muscle.

Kintscher U, Law RE.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E287-91. Review.

19.

A PPAR agonist improves TNF-alpha-induced insulin resistance of adipose tissue in mice.

Shibasaki M, Takahashi K, Itou T, Bujo H, Saito Y.

Biochem Biophys Res Commun. 2003 Sep 19;309(2):419-24.

PMID:
12951066
20.

A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat.

Oakes ND, Kennedy CJ, Jenkins AB, Laybutt DR, Chisholm DJ, Kraegen EW.

Diabetes. 1994 Oct;43(10):1203-10.

PMID:
7926289
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