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Results: 1 to 20 of 123

1.

Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

Rondón AG, Jimeno S, García-Rubio M, Aguilera A.

J Biol Chem. 2003 Oct 3;278(40):39037-43. Epub 2003 Jul 18.

PMID:
12871933
[PubMed - indexed for MEDLINE]
Free Article
2.

TREX is a conserved complex coupling transcription with messenger RNA export.

Strässer K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondón AG, Aguilera A, Struhl K, Reed R, Hurt E.

Nature. 2002 May 16;417(6886):304-8. Epub 2002 Apr 28.

PMID:
11979277
[PubMed - indexed for MEDLINE]
3.

Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.

García-Rubio M, Chávez S, Huertas P, Tous C, Jimeno S, Luna R, Aguilera A.

Mol Genet Genomics. 2008 Feb;279(2):123-32. Epub 2007 Oct 25.

PMID:
17960421
[PubMed - indexed for MEDLINE]
4.

Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants.

Jimeno S, Luna R, García-Rubio M, Aguilera A.

Mol Cell Biol. 2006 Jun;26(12):4387-98.

PMID:
16738307
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Jimeno S, Rondón AG, Luna R, Aguilera A.

EMBO J. 2002 Jul 1;21(13):3526-35.

PMID:
12093753
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.

Huertas P, García-Rubio ML, Wellinger RE, Luna R, Aguilera A.

Mol Cell Biol. 2006 Oct;26(20):7451-65. Epub 2006 Aug 14.

PMID:
16908536
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.

Gallardo M, Luna R, Erdjument-Bromage H, Tempst P, Aguilera A.

J Biol Chem. 2003 Jun 27;278(26):24225-32. Epub 2003 Apr 17.

PMID:
12702719
[PubMed - indexed for MEDLINE]
Free Article
8.

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.

González-Aguilera C, Tous C, Gómez-González B, Huertas P, Luna R, Aguilera A.

Mol Biol Cell. 2008 Oct;19(10):4310-8. doi: 10.1091/mbc.E08-04-0355. Epub 2008 Jul 30.

PMID:
18667528
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants.

Rougemaille M, Gudipati RK, Olesen JR, Thomsen R, Seraphin B, Libri D, Jensen TH.

EMBO J. 2007 May 2;26(9):2317-26. Epub 2007 Apr 5.

PMID:
17410208
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Role of transcription in plasmid maintenance in the hpr1Delta mutant of Saccharomyces cerevisiae.

Merker RJ, Klein HL.

Mol Cell Biol. 2002 Dec;22(24):8763-73.

PMID:
12446793
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.

Huertas P, Aguilera A.

Mol Cell. 2003 Sep;12(3):711-21.

PMID:
14527416
[PubMed - indexed for MEDLINE]
12.

Molecular evidence for a positive role of Spt4 in transcription elongation.

Rondón AG, García-Rubio M, González-Barrera S, Aguilera A.

EMBO J. 2003 Feb 3;22(3):612-20.

PMID:
12554661
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex.

Wellinger RE, Prado F, Aguilera A.

Mol Cell Biol. 2006 Apr;26(8):3327-34.

PMID:
16581804
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Messenger RNAs are recruited for nuclear export during transcription.

Lei EP, Krebber H, Silver PA.

Genes Dev. 2001 Jul 15;15(14):1771-82.

PMID:
11459827
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation.

Saguez C, Schmid M, Olesen JR, Ghazy MA, Qu X, Poulsen MB, Nasser T, Moore C, Jensen TH.

Mol Cell. 2008 Jul 11;31(1):91-103. doi: 10.1016/j.molcel.2008.04.030.

PMID:
18614048
[PubMed - indexed for MEDLINE]
Free Article
16.

Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II.

Meinel DM, Burkert-Kautzsch C, Kieser A, O'Duibhir E, Siebert M, Mayer A, Cramer P, Söding J, Holstege FC, Sträßer K.

PLoS Genet. 2013 Nov;9(11):e1003914. doi: 10.1371/journal.pgen.1003914. Epub 2013 Nov 14.

PMID:
24244187
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A new connection of mRNP biogenesis and export with transcription-coupled repair.

Gaillard H, Wellinger RE, Aguilera A.

Nucleic Acids Res. 2007;35(12):3893-906. Epub 2007 May 30.

PMID:
17537816
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Nap1 links transcription elongation, chromatin assembly, and messenger RNP complex biogenesis.

Del Rosario BC, Pemberton LF.

Mol Cell Biol. 2008 Apr;28(7):2113-24. doi: 10.1128/MCB.02136-07. Epub 2008 Jan 28.

PMID:
18227150
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Differential export requirements for shuttling serine/arginine-type mRNA-binding proteins.

Häcker S, Krebber H.

J Biol Chem. 2004 Feb 13;279(7):5049-52. Epub 2003 Dec 15.

PMID:
14676199
[PubMed - indexed for MEDLINE]
Free Article
20.

Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.

Hieronymus H, Silver PA.

Nat Genet. 2003 Feb;33(2):155-61. Epub 2003 Jan 13.

PMID:
12524544
[PubMed - indexed for MEDLINE]

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