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Items: 1 to 20 of 153

1.

Proinsulin-a pathogenic autoantigen in type 1 diabetes.

Narendran P, Mannering SI, Harrison LC.

Autoimmun Rev. 2003 Jun;2(4):204-10. Review.

PMID:
12848947
2.

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes.

Chen W, Bergerot I, Elliott JF, Harrison LC, Abiru N, Eisenbarth GS, Delovitch TL.

J Immunol. 2001 Nov 1;167(9):4926-35.

3.

A proinsulin 74-90-derived protease-resistant, altered peptide ligand increases TGF-beta 1 secretion in PBMC from patients with type 1 diabetes mellitus.

van Aalst D, Kalbacher H, Palesch D, Zou F, Spyrantis A, Rosinger S, Boehm BO, Burster T.

J Leukoc Biol. 2010 May;87(5):943-8. doi: 10.1189/jlb.1109713.

4.

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW.

J Clin Invest. 2006 Dec;116(12):3258-65.

5.

Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.

Steptoe RJ, Ritchie JM, Harrison LC.

J Clin Invest. 2003 May;111(9):1357-63.

6.

Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes.

Narendran P, Williams AJ, Elsegood K, Leech NJ, Dayan CM.

Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):52-9.

PMID:
12592644
7.
8.

T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects.

Semana G, Gausling R, Jackson RA, Hafler DA.

J Autoimmun. 1999 Jun;12(4):259-67.

PMID:
10330297
9.

Proinsulin: a unique autoantigen triggering autoimmune diabetes.

You S, Chatenoud L.

J Clin Invest. 2006 Dec;116(12):3108-10.

10.

Immune markers of disease and therapeutic intervention in type 1 diabetes.

Roep BO.

Novartis Found Symp. 2008;292:159-71; discussion 171-3, 202-3.

PMID:
19203098
11.

Insulin--a primary autoantigen in type 1 diabetes?

Wong FS.

Trends Mol Med. 2005 Oct;11(10):445-8. Review.

PMID:
16150642
12.

Thymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes.

Geenen V, Mottet M, Dardenne O, Kermani H, Martens H, Francois JM, Galleni M, Hober D, Rahmouni S, Moutschen M.

Curr Opin Pharmacol. 2010 Aug;10(4):461-72. doi: 10.1016/j.coph.2010.04.005. Epub 2010 Apr 29. Review.

PMID:
20434402
13.

Autoimmune mechanisms in type 1 diabetes.

Knip M, Siljander H.

Autoimmun Rev. 2008 Jul;7(7):550-7. doi: 10.1016/j.autrev.2008.04.008. Epub 2008 Apr 30. Review.

PMID:
18625444
14.

Insulin as a primary autoantigen for type 1A diabetes.

Jasinski JM, Eisenbarth GS.

Clin Dev Immunol. 2005 Sep;12(3):181-6. Review.

15.

Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes.

Every AL, Kramer DR, Mannering SI, Lew AM, Harrison LC.

J Immunol. 2006 Apr 15;176(8):4608-15.

16.

Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.

Hassainya Y, Garcia-Pons F, Kratzer R, Lindo V, Greer F, Lemonnier FA, Niedermann G, van Endert PM.

Diabetes. 2005 Jul;54(7):2053-9.

17.

Type 1 diabetes: lessons for other autoimmune diseases?

Harrison LC, Honeyman MC, Morahan G, Wentworth JM, Elkassaby S, Colman PG, Fourlanos S.

J Autoimmun. 2008 Nov;31(3):306-10. doi: 10.1016/j.jaut.2008.04.026. Epub 2008 Jun 16.

PMID:
18558477
18.

The sentinel role of CD8 T cells in regulating CD4 T cell responses to proinsulin in beta-islet cell autoimmunity.

Batarelo V, Durinovic-Belló I.

Ann N Y Acad Sci. 2008 Dec;1150:270-2. doi: 10.1196/annals.1447.047.

PMID:
19120311
19.

Deleting islet autoimmunity.

Liu E, Li M, Jasinski J, Kobayashi M, Gianani R, Nakayama M, Eisenbarth GS.

Cell Biochem Biophys. 2007;48(2-3):177-82. Review.

PMID:
17709887
20.

Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.

Durinovic-Belló I, Schlosser M, Riedl M, Maisel N, Rosinger S, Kalbacher H, Deeg M, Ziegler M, Elliott J, Roep BO, Karges W, Boehm BO.

Diabetologia. 2004 Mar;47(3):439-50. Epub 2004 Jan 24.

PMID:
14745491
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