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Items: 1 to 20 of 83

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Inhibitors targeting the LFA-1/ICAM-1 cell-adhesion interaction: design and mechanism of action.

Zimmerman T, Blanco FJ.

Curr Pharm Des. 2008;14(22):2128-39. Review.

PMID:
18781967
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4.

Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases.

Yusuf-Makagiansar H, Anderson ME, Yakovleva TV, Murray JS, Siahaan TJ.

Med Res Rev. 2002 Mar;22(2):146-67. Review.

PMID:
11857637
5.

Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction.

Takahashi HK, Iwagaki H, Yagi T, Kanke T, Liu K, Yoshino T, Tanaka N, Nishibori M.

Clin Immunol. 2007 Jun;123(3):324-32. Epub 2007 May 4.

PMID:
17482516
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Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain.

Ullrich T, Baumann K, Welzenbach K, Schmutz S, Camenisch G, Meingassner JG, Weitz-Schmidt G.

Bioorg Med Chem Lett. 2004 May 17;14(10):2483-7.

PMID:
15109637
9.

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

Puigdomènech I, Massanella M, Izquierdo-Useros N, Ruiz-Hernandez R, Curriu M, Bofill M, Martinez-Picado J, Juan M, Clotet B, Blanco J.

Retrovirology. 2008 Mar 31;5:32. doi: 10.1186/1742-4690-5-32.

11.

Development of a cell-free binding assay for rat ICAM-1/LFA-1 interactions using a novel anti-rat LFA-1 monoclonal antibody and comparison with a cell-based assay.

Mukasa R, Satoh A, Tominaga Y, Yamazaki M, Matsumoto K, Iigo Y, Higashida T, Kita Y, Miyasaka M, Takashi T.

J Immunol Methods. 1999 Aug 31;228(1-2):69-79.

PMID:
10556544
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13.

Virtual screening leads to the discovery of an effective antagonist of lymphocyte function-associated antigen-1.

Shoda M, Harada T, Yano K, Stahura FL, Himeno T, Shiojiri S, Kogami Y, Kouji H, Bajorath J.

ChemMedChem. 2007 Apr;2(4):515-21.

PMID:
17340656
14.

HMG-CoA reductase inhibitors as immunomodulators: potential use in transplant rejection.

Raggatt LJ, Partridge NC.

Drugs. 2002;62(15):2185-91. Review.

PMID:
12381218
15.

Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells.

Takahashi HK, Mori S, Iwagaki H, Yoshino T, Tanaka N, Nishibori M.

Clin Immunol. 2005 Sep;116(3):211-6.

PMID:
15936988
16.

Synergistic inhibitory activity of alpha- and beta-LFA-1 peptides on LFA-1/ICAM-1 interaction.

Yusuf-Makagiansar H, Makagiansar IT, Hu Y, Siahaan TJ.

Peptides. 2001 Dec;22(12):1955-62.

PMID:
11786177
17.

Membrane-proximal signaling events in beta-2 integrin activation.

Kellersch B, Kolanus W.

Results Probl Cell Differ. 2006;43:245-57. Review.

PMID:
17068975
18.

IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways.

Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T.

J Immunol. 2006 Dec 1;177(11):7579-87.

20.

Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes.

Takahashi HK, Mori S, Iwagaki H, Yoshino T, Tanaka N, Weitz-Schmidt G, Nishibori M.

J Leukoc Biol. 2005 Mar;77(3):400-7. Epub 2004 Dec 23.

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