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Results: 1 to 20 of 191

Similar articles for PubMed (Select 12727824)

1.

Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.

Anders M, Christian C, McMahon M, McCormick F, Korn WM.

Cancer Res. 2003 May 1;63(9):2088-95.

2.

The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.

Boldt S, Weidle UH, Kolch W.

Exp Cell Res. 2003 Feb 1;283(1):80-90.

PMID:
12565821
3.

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.

Woods D, Cherwinski H, Venetsanakos E, Bhat A, Gysin S, Humbert M, Bray PF, Saylor VL, McMahon M.

Mol Cell Biol. 2001 May;21(9):3192-205.

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.

Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA.

Cancer Res. 2004 Oct 1;64(19):7099-109.

6.

Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.

Ikenoue T, Hikiba Y, Kanai F, Aragaki J, Tanaka Y, Imamura J, Imamura T, Ohta M, Ijichi H, Tateishi K, Kawakami T, Matsumura M, Kawabe T, Omata M.

Cancer Res. 2004 May 15;64(10):3428-35.

7.

A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.

Dhillon AS, Meikle S, Peyssonnaux C, Grindlay J, Kaiser C, Steen H, Shaw PE, Mischak H, Eychène A, Kolch W.

Mol Cell Biol. 2003 Mar;23(6):1983-93.

8.

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP.

Yeung K, Seitz T, Li S, Janosch P, McFerran B, Kaiser C, Fee F, Katsanakis KD, Rose DW, Mischak H, Sedivy JM, Kolch W.

Nature. 1999 Sep 9;401(6749):173-7.

PMID:
10490027
9.

Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.

Guha S, Lunn JA, Santiskulvong C, Rozengurt E.

Cancer Res. 2003 May 15;63(10):2379-87.

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Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells.

Lefevre G, Calipel A, Mouriaux F, Hecquet C, Malecaze F, Mascarelli F.

Oncogene. 2003 Dec 4;22(55):8813-22.

PMID:
14654778
15.

c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

Iijima Y, Laser M, Shiraishi H, Willey CD, Sundaravadivel B, Xu L, McDermott PJ, Kuppuswamy D.

J Biol Chem. 2002 Jun 21;277(25):23065-75. Epub 2002 Apr 8.

16.

Raf-1 activation suppresses neuroendocrine marker and hormone levels in human gastrointestinal carcinoid cells.

Sippel RS, Carpenter JE, Kunnimalaiyaan M, Lagerholm S, Chen H.

Am J Physiol Gastrointest Liver Physiol. 2003 Aug;285(2):G245-54.

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PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.

Coutant A, Rescan C, Gilot D, Loyer P, Guguen-Guillouzo C, Baffet G.

Hepatology. 2002 Nov;36(5):1079-88.

PMID:
12395317
19.

Ras/Raf signalling and emerging pharmacotherapeutic targets.

Kolch W.

Expert Opin Pharmacother. 2002 Jun;3(6):709-18. Review.

PMID:
12036410
20.

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway.

Paumelle R, Tulasne D, Kherrouche Z, Plaza S, Leroy C, Reveneau S, Vandenbunder B, Fafeur V.

Oncogene. 2002 Apr 4;21(15):2309-19. Erratum in: Oncogene 2002 Jul 18;21(31):4872. Tulashe, David [corrected to Tulasne, David]; Reveneau, Syline [corrected to Reveneau, Sylvie].

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