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Results: 1 to 20 of 218

1.

The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation.

York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL.

Immunity. 2003 Mar;18(3):429-40.

PMID:
12648459
[PubMed - indexed for MEDLINE]
2.

Proteolysis and class I major histocompatibility complex antigen presentation.

York IA, Goldberg AL, Mo XY, Rock KL.

Immunol Rev. 1999 Dec;172:49-66. Review.

PMID:
10631936
[PubMed - indexed for MEDLINE]
3.

Post-proteasomal antigen processing for major histocompatibility complex class I presentation.

Rock KL, York IA, Goldberg AL.

Nat Immunol. 2004 Jul;5(7):670-7. Review.

PMID:
15224092
[PubMed - indexed for MEDLINE]
4.

Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases.

Saveanu L, Fruci D, van Endert P.

Mol Immunol. 2002 Oct;39(3-4):203-15. Review.

PMID:
12200051
[PubMed - indexed for MEDLINE]
5.

Generating MHC class I ligands from viral gene products.

Yewdell J, Antón LC, Bacik I, Schubert U, Snyder HL, Bennink JR.

Immunol Rev. 1999 Dec;172:97-108. Review.

PMID:
10631940
[PubMed - indexed for MEDLINE]
6.

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.

Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL.

J Biol Chem. 2001 Sep 28;276(39):36474-81. Epub 2001 Jul 30.

PMID:
11479311
[PubMed - indexed for MEDLINE]
Free Article
7.

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, van Veelen P, Janssen H, Calafat J, Drijfhout JW, Neefjes J.

Immunity. 2003 Jan;18(1):97-108.

PMID:
12530979
[PubMed - indexed for MEDLINE]
8.

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

Goldberg AL, Cascio P, Saric T, Rock KL.

Mol Immunol. 2002 Oct;39(3-4):147-64. Review.

PMID:
12200047
[PubMed - indexed for MEDLINE]
9.

Thimet oligopeptidase (EC 3.4.24.15), a novel protein on the route of MHC class I antigen presentation.

Silva CL, Portaro FC, Bonato VL, de Camargo AC, Ferro ES.

Biochem Biophys Res Commun. 1999 Feb 24;255(3):591-5.

PMID:
10049755
[PubMed - indexed for MEDLINE]
10.

The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway.

Kunisawa J, Shastri N.

Mol Cell. 2003 Sep;12(3):565-76.

PMID:
14527404
[PubMed - indexed for MEDLINE]
11.

Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.

Portaro FC, Gomes MD, Cabrera A, Fernandes BL, Silva CL, Ferro ES, Juliano L, de Camargo AC.

Biochem Biophys Res Commun. 1999 Feb 24;255(3):596-601.

PMID:
10049756
[PubMed - indexed for MEDLINE]
12.

Role of proteasomes in antigen presentation.

Gaczynska M, Rock KL, Goldberg AL.

Enzyme Protein. 1993;47(4-6):354-69. Review.

PMID:
7697133
[PubMed - indexed for MEDLINE]
13.

Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases.

Saric T, Graef CI, Goldberg AL.

J Biol Chem. 2004 Nov 5;279(45):46723-32. Epub 2004 Aug 24.

PMID:
15328361
[PubMed - indexed for MEDLINE]
Free Article
14.

ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.

Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S.

Nature. 2003 Sep 25;425(6956):397-402.

PMID:
14508489
[PubMed - indexed for MEDLINE]
Free Article
15.
16.

Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation.

Callahan MK, Garg M, Srivastava PK.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1662-7. doi: 10.1073/pnas.0711365105. Epub 2008 Jan 23.

PMID:
18216248
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MHC-encoded proteasome subunits LMP2 and LMP7 are not required for efficient antigen presentation.

Yewdell J, Lapham C, Bacik I, Spies T, Bennink J.

J Immunol. 1994 Feb 1;152(3):1163-70.

PMID:
8301122
[PubMed - indexed for MEDLINE]
18.

Processing and delivery of peptides presented by MHC class I molecules.

Lehner PJ, Cresswell P.

Curr Opin Immunol. 1996 Feb;8(1):59-67. Review.

PMID:
8729447
[PubMed - indexed for MEDLINE]
19.

Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.

López D, Gil-Torregrosa BC, Bergmann C, Del Val M.

J Immunol. 2000 May 15;164(10):5070-7.

PMID:
10799863
[PubMed - indexed for MEDLINE]
Free Article
20.

Heat shock protein-chaperoned peptides but not free peptides introduced into the cytosol are presented efficiently by major histocompatibility complex I molecules.

Binder RJ, Blachere NE, Srivastava PK.

J Biol Chem. 2001 May 18;276(20):17163-71. Epub 2001 Mar 8.

PMID:
11278929
[PubMed - indexed for MEDLINE]
Free Article
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