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Results: 1 to 20 of 118

1.

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.

Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J.

Cell. 2003 Mar 7;112(5):659-72. Erratum in: Cell. 2003 Oct 17;115(2):241.

PMID:
12628186
[PubMed - indexed for MEDLINE]
2.

SET-ting the stage for life and death.

Chakravarti D, Hong R.

Cell. 2003 Mar 7;112(5):589-91. Review.

PMID:
12628178
[PubMed - indexed for MEDLINE]
3.

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.

Chowdhury D, Beresford PJ, Zhu P, Zhang D, Sung JS, Demple B, Perrino FW, Lieberman J.

Mol Cell. 2006 Jul 7;23(1):133-42.

PMID:
16818237
[PubMed - indexed for MEDLINE]
Free Article
4.

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.

Fan Z, Beresford PJ, Zhang D, Xu Z, Novina CD, Yoshida A, Pommier Y, Lieberman J.

Nat Immunol. 2003 Feb;4(2):145-53. Epub 2003 Jan 13.

PMID:
12524539
[PubMed - indexed for MEDLINE]
5.

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.

Fan Z, Beresford PJ, Zhang D, Lieberman J.

Mol Cell Biol. 2002 Apr;22(8):2810-20.

PMID:
11909973
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells.

Zhao T, Zhang H, Guo Y, Zhang Q, Hua G, Lu H, Hou Q, Liu H, Fan Z.

Cell Death Differ. 2007 Mar;14(3):489-99. Epub 2006 Sep 29.

PMID:
17008916
[PubMed - indexed for MEDLINE]
Free Article
7.

Nuclear war: the granzyme A-bomb.

Lieberman J, Fan Z.

Curr Opin Immunol. 2003 Oct;15(5):553-9. Review.

PMID:
14499264
[PubMed - indexed for MEDLINE]
8.

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.

Beresford PJ, Zhang D, Oh DY, Fan Z, Greer EL, Russo ML, Jaju M, Lieberman J.

J Biol Chem. 2001 Nov 16;276(46):43285-93. Epub 2001 Sep 12.

PMID:
11555662
[PubMed - indexed for MEDLINE]
Free Article
9.

Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na(+), K(+)-ATPase.

lizuka N, Miyamoto K, Tangoku A, Hayashi H, Hazama S, Yoshino S, Yoshimura K, Hirose K, Yoshida H, Oka M.

Br J Cancer. 2000 Nov;83(9):1209-15.

PMID:
11027435
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.

Hartsough MT, Morrison DK, Salerno M, Palmieri D, Ouatas T, Mair M, Patrick J, Steeg PS.

J Biol Chem. 2002 Aug 30;277(35):32389-99. Epub 2002 Jun 24.

PMID:
12105213
[PubMed - indexed for MEDLINE]
Free Article
11.

Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis.

Negroni A, Venturelli D, Tanno B, Amendola R, Ransac S, Cesi V, Calabretta B, Raschellà G.

Cell Death Differ. 2000 Sep;7(9):843-50.

PMID:
11042679
[PubMed - indexed for MEDLINE]
Free Article
12.

Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis.

Martinvalet D, Zhu P, Lieberman J.

Immunity. 2005 Mar;22(3):355-70.

PMID:
15780992
[PubMed - indexed for MEDLINE]
Free Article
13.

Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma.

Niitsu N, Nakamine H, Okamoto M, Akamatsu H, Honma Y, Higashihara M, Okabe-Kado J, Hirano M; Adult Lymphoma Treatment Study Group, ALTSG.

Br J Haematol. 2003 Nov;123(4):621-30.

PMID:
14616965
[PubMed - indexed for MEDLINE]
14.
15.

Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).

Cheng S, Alfonso-Jaume MA, Mertens PR, Lovett DH.

Biochem J. 2002 Sep 15;366(Pt 3):807-16.

PMID:
12010125
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Regulators affecting the metastasis suppressor activity of Nm23-H1.

Kim HD, Youn B, Kim TS, Kim SH, Shin HS, Kim J.

Mol Cell Biochem. 2009 Sep;329(1-2):167-73. doi: 10.1007/s11010-009-0109-2. Epub 2009 Apr 18. Review.

PMID:
19377884
[PubMed - indexed for MEDLINE]
17.

[Amplification, clone and identification of the specific fragments of tumor metastasis-suppressor gene nm23-H1 and nm23-H2].

Li C, Lu Y, Wang R.

Hua Xi Kou Qiang Yi Xue Za Zhi. 1997 Nov;15(4):322-4. Chinese.

PMID:
11479979
[PubMed - indexed for MEDLINE]
Free Article
18.

NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.

Ma D, Xing Z, Liu B, Pedigo NG, Zimmer SG, Bai Z, Postel EH, Kaetzel DM.

J Biol Chem. 2002 Jan 11;277(2):1560-7. Epub 2001 Nov 1.

PMID:
11694515
[PubMed - indexed for MEDLINE]
Free Article
19.

P53 is a regulator of the metastasis suppressor gene Nm23-H1.

Chen SL, Wu YS, Shieh HY, Yen CC, Shen JJ, Lin KH.

Mol Carcinog. 2003 Apr;36(4):204-14.

PMID:
12669312
[PubMed - indexed for MEDLINE]
20.

Granzyme M directly cleaves inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation.

Lu H, Hou Q, Zhao T, Zhang H, Zhang Q, Wu L, Fan Z.

J Immunol. 2006 Jul 15;177(2):1171-8.

PMID:
16818775
[PubMed - indexed for MEDLINE]
Free Article

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