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Items: 1 to 20 of 234

1.

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA.

J Biol Chem. 2003 Apr 18;278(16):13740-6. Epub 2003 Jan 30.

2.

Insulin resistance-inducing cytokines differentially regulate SOCS mRNA expression via growth factor- and Jak/Stat-signaling pathways in 3T3-L1 adipocytes.

Fasshauer M, Kralisch S, Klier M, Lossner U, Bluher M, Klein J, Paschke R.

J Endocrinol. 2004 Apr;181(1):129-38.

3.

Interleukin-6 induces cellular insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Mooney RA.

Diabetes. 2002 Dec;51(12):3391-9.

4.
5.

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.

Cell Signal. 2010 May;22(5):791-800. doi: 10.1016/j.cellsig.2010.01.003. Epub 2010 Jan 11.

PMID:
20067833
6.

IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.

Brand S, Dambacher J, Beigel F, Zitzmann K, Heeg MH, Weiss TS, Prüfer T, Olszak T, Steib CJ, Storr M, Göke B, Diepolder H, Bilzer M, Thasler WE, Auernhammer CJ.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1019-28. Epub 2007 Jan 4.

7.

Activation of SOCS-3 by resistin.

Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA.

Mol Cell Biol. 2005 Feb;25(4):1569-75.

8.

Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism.

Li L, Grønning LM, Anderson PO, Li S, Edvardsen K, Johnston J, Kioussis D, Shepherd PR, Wang P.

J Biol Chem. 2004 Aug 13;279(33):34107-14. Epub 2004 Apr 27.

9.

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells.

Weigert C, Hennige AM, Lehmann R, Brodbeck K, Baumgartner F, Schaüble M, Häring HU, Schleicher ED.

J Biol Chem. 2006 Mar 17;281(11):7060-7. Epub 2006 Jan 17.

10.

Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation.

Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, Bazzoni F.

J Immunol. 2002 Jun 15;168(12):6404-11.

11.

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

Emanuelli B, Peraldi P, Filloux C, Chavey C, Freidinger K, Hilton DJ, Hotamisligil GS, Van Obberghen E.

J Biol Chem. 2001 Dec 21;276(51):47944-9. Epub 2001 Oct 16.

12.

The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells.

Emanuelli B, Glondu M, Filloux C, Peraldi P, Van Obberghen E.

Diabetes. 2004 Dec;53 Suppl 3:S97-S103.

15.

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling.

Pezet A, Favre H, Kelly PA, Edery M.

J Biol Chem. 1999 Aug 27;274(35):24497-502.

16.

The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.

Serrano-Marco L, Barroso E, El Kochairi I, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M.

Diabetologia. 2012 Mar;55(3):743-51. doi: 10.1007/s00125-011-2401-4. Epub 2011 Dec 17.

PMID:
22179221
17.

Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance.

Mooney RA, Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y, Furlanetto RW.

J Biol Chem. 2001 Jul 13;276(28):25889-93. Epub 2001 May 7.

18.
19.

Src family kinase-independent signal transduction and gene induction by leukemia inhibitory factor.

Laszlo GS, Nathanson NM.

J Biol Chem. 2003 Jul 25;278(30):27750-7. Epub 2003 May 21.

20.

Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate.

Schnyder B, Lahm H, Pittet M, Schnyder-Candrian S.

J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):213-28.

PMID:
12503617
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