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Results: 1 to 20 of 319

1.

Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands.

Suto RK, Edayathumangalam RS, White CL, Melander C, Gottesfeld JM, Dervan PB, Luger K.

J Mol Biol. 2003 Feb 14;326(2):371-80.

PMID:
12559907
[PubMed - indexed for MEDLINE]
2.

Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides.

Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB.

J Mol Biol. 2001 Jun 8;309(3):615-29.

PMID:
11397084
[PubMed - indexed for MEDLINE]
3.

Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution.

Davey CA, Sargent DF, Luger K, Maeder AW, Richmond TJ.

J Mol Biol. 2002 Jun 21;319(5):1097-113.

PMID:
12079350
[PubMed - indexed for MEDLINE]
4.

Nucleosomes in solution exist as a mixture of twist-defect states.

Edayathumangalam RS, Weyermann P, Dervan PB, Gottesfeld JM, Luger K.

J Mol Biol. 2005 Jan 7;345(1):103-14.

PMID:
15567414
[PubMed - indexed for MEDLINE]
5.

Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.

Chenoweth DM, Meier JL, Dervan PB.

Angew Chem Int Ed Engl. 2013 Jan 2;52(1):415-8. doi: 10.1002/anie.201205775. Epub 2012 Sep 14.

PMID:
22987334
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Blocking transcription through a nucleosome with synthetic DNA ligands.

Gottesfeld JM, Belitsky JM, Melander C, Dervan PB, Luger K.

J Mol Biol. 2002 Aug 9;321(2):249-63.

PMID:
12144782
[PubMed - indexed for MEDLINE]
7.

Structure and dynamics of nucleosomal DNA.

Muthurajan UM, Park YJ, Edayathumangalam RS, Suto RK, Chakravarthy S, Dyer PN, Luger K.

Biopolymers. 2003 Apr;68(4):547-56.

PMID:
12666179
[PubMed - indexed for MEDLINE]
8.

Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.

Westrate L, Mackay H, Brown T, Nguyen B, Kluza J, Wilson WD, Lee M, Hartley JA.

Biochemistry. 2009 Jun 23;48(24):5679-88. doi: 10.1021/bi900242t.

PMID:
19419200
[PubMed - indexed for MEDLINE]
9.

Two DNA-binding sites on the globular domain of histone H5 are required for binding to both bulk and 5 S reconstituted nucleosomes.

Duggan MM, Thomas JO.

J Mol Biol. 2000 Nov 17;304(1):21-33.

PMID:
11071807
[PubMed - indexed for MEDLINE]
10.

Linker DNA and H1-dependent reorganization of histone-DNA interactions within the nucleosome.

Lee KM, Hayes JJ.

Biochemistry. 1998 Jun 16;37(24):8622-8.

PMID:
9628723
[PubMed - indexed for MEDLINE]
11.

Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand.

McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM.

J Mol Biol. 1999 Mar 5;286(4):973-81.

PMID:
10047474
[PubMed - indexed for MEDLINE]
12.

Targeting the minor groove of DNA.

Wemmer DE, Dervan PB.

Curr Opin Struct Biol. 1997 Jun;7(3):355-61. Review.

PMID:
9204277
[PubMed - indexed for MEDLINE]
13.

DNA nanomechanics in the nucleosome.

Becker NB, Everaers R.

Structure. 2009 Apr 15;17(4):579-89. doi: 10.1016/j.str.2009.01.013.

PMID:
19368891
[PubMed - indexed for MEDLINE]
Free Article
14.

Theory of nucleosome corkscrew sliding in the presence of synthetic DNA ligands.

Mohammad-Rafiee F, Kulić IM, Schiessel H.

J Mol Biol. 2004 Nov 12;344(1):47-58.

PMID:
15504401
[PubMed - indexed for MEDLINE]
15.

The structure of DNA in the nucleosome core.

Richmond TJ, Davey CA.

Nature. 2003 May 8;423(6936):145-50.

PMID:
12736678
[PubMed - indexed for MEDLINE]
16.

Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.

Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M.

Biochemistry. 2004 Sep 28;43(38):12249-57.

PMID:
15379563
[PubMed - indexed for MEDLINE]
17.

Hx, a novel fluorescent, minor groove and sequence specific recognition element: design, synthesis, and DNA binding properties of p-anisylbenzimidazole-imidazole/pyrrole-containing polyamides.

Chavda S, Liu Y, Babu B, Davis R, Sielaff A, Ruprich J, Westrate L, Tronrud C, Ferguson A, Franks A, Tzou S, Adkins C, Rice T, Mackay H, Kluza J, Tahir SA, Lin S, Kiakos K, Bruce CD, Wilson WD, Hartley JA, Lee M.

Biochemistry. 2011 Apr 19;50(15):3127-36. doi: 10.1021/bi102028a. Epub 2011 Mar 25.

PMID:
21388229
[PubMed - indexed for MEDLINE]
18.

DNA recognition. Reading the minor groove.

Hélène C.

Nature. 1998 Jan 29;391(6666):436-8. No abstract available.

PMID:
9461206
[PubMed - indexed for MEDLINE]
19.

Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA.

White S, Baird EE, Dervan PB.

Biochemistry. 1996 Sep 24;35(38):12532-7.

PMID:
8823190
[PubMed - indexed for MEDLINE]
20.

Association of the anticancer antibiotic chromomycin A(3) with the nucleosome: role of core histone tail domains in the binding process.

Mir MA, Dasgupta D.

Biochemistry. 2001 Sep 25;40(38):11578-85.

PMID:
11560508
[PubMed - indexed for MEDLINE]

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