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Items: 1 to 20 of 176

1.

The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42.

Cai D, Felekkis KN, Near RI, O'Neill GM, van Seventer JM, Golemis EA, Lerner A.

J Immunol. 2003 Jan 15;170(2):969-78.

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AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.

Cai D, Iyer A, Felekkis KN, Near RI, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A.

Cancer Res. 2003 Oct 15;63(20):6802-8.

4.

Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.

Manié SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, Druker BJ, Avraham H, Haghayeghi N, Sattler M, Salgia R, Griffin JD, Golemis EA, Freedman AS.

J Biol Chem. 1997 Feb 14;272(7):4230-6.

5.

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes.

del Pozo MA, Vicente-Manzanares M, Tejedor R, Serrador JM, Sánchez-Madrid F.

Eur J Immunol. 1999 Nov;29(11):3609-20.

6.

The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.

Baird D, Feng Q, Cerione RA.

Curr Biol. 2005 Jan 11;15(1):1-10.

9.

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

Gotoh T, Cai D, Tian X, Feig LA, Lerner A.

J Biol Chem. 2000 Sep 29;275(39):30118-23.

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The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

Haddad E, Zugaza JL, Louache F, Debili N, Crouin C, Schwarz K, Fischer A, Vainchenker W, Bertoglio J.

Blood. 2001 Jan 1;97(1):33-8.

12.

AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines.

Cai D, Clayton LK, Smolyar A, Lerner A.

J Immunol. 1999 Aug 15;163(4):2104-12.

14.

Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.

Phee H, Abraham RT, Weiss A.

Nat Immunol. 2005 Jun;6(6):608-17. Epub 2005 May 1.

PMID:
15864311
15.

Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.

Feng Q, Albeck JG, Cerione RA, Yang W.

J Biol Chem. 2002 Feb 15;277(7):5644-50. Epub 2001 Dec 10.

16.

The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions.

Bargon SD, Gunning PW, O'Neill GM.

Biochim Biophys Acta. 2005 Dec 15;1746(2):143-54. Epub 2005 Nov 14.

17.

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

Li Z, Hannigan M, Mo Z, Liu B, Lu W, Wu Y, Smrcka AV, Wu G, Li L, Liu M, Huang CK, Wu D.

Cell. 2003 Jul 25;114(2):215-27.

18.

The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.

Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S, Ishigatsubo Y.

Genes Cells. 2004 Mar;9(3):193-204.

19.

PAK1 negatively regulates the activity of the Rho exchange factor NET1.

Alberts AS, Qin H, Carr HS, Frost JA.

J Biol Chem. 2005 Apr 1;280(13):12152-61. Epub 2005 Jan 31.

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