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Results: 1 to 20 of 162

1.

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A.

Lowe ED, Tews I, Cheng KY, Brown NR, Gul S, Noble ME, Gamblin SJ, Johnson LN.

Biochemistry. 2002 Dec 31;41(52):15625-34.

PMID:
12501191
[PubMed - indexed for MEDLINE]
2.

Cyclin B and cyclin A confer different substrate recognition properties on CDK2.

Brown NR, Lowe ED, Petri E, Skamnaki V, Antrobus R, Johnson LN.

Cell Cycle. 2007 Jun 1;6(11):1350-9. Epub 2007 Jun 11.

PMID:
17495531
[PubMed - indexed for MEDLINE]
Free Article
3.

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases.

Brown NR, Noble ME, Endicott JA, Johnson LN.

Nat Cell Biol. 1999 Nov;1(7):438-43.

PMID:
10559988
[PubMed - indexed for MEDLINE]
4.

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

Schulman BA, Lindstrom DL, Harlow E.

Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10453-8.

PMID:
9724724
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4.

Leng X, Noble M, Adams PD, Qin J, Harper JW.

Mol Cell Biol. 2002 Apr;22(7):2242-54.

PMID:
11884610
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2.

Kitagawa M, Higashi H, Jung HK, Suzuki-Takahashi I, Ikeda M, Tamai K, Kato J, Segawa K, Yoshida E, Nishimura S, Taya Y.

EMBO J. 1996 Dec 16;15(24):7060-9.

PMID:
9003781
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A.

Luciani MG, Hutchins JR, Zheleva D, Hupp TR.

J Mol Biol. 2000 Jul 14;300(3):503-18.

PMID:
10884347
[PubMed - indexed for MEDLINE]
8.

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation.

Xiao B, Spencer J, Clements A, Ali-Khan N, Mittnacht S, Broceño C, Burghammer M, Perrakis A, Marmorstein R, Gamblin SJ.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2363-8. Epub 2003 Feb 21.

PMID:
12598654
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phosphorylation of E2F-1 by cyclin A-cdk2.

Kitagawa M, Higashi H, Suzuki-Takahashi I, Segawa K, Hanks SK, Taya Y, Nishimura S, Okuyama A.

Oncogene. 1995 Jan 19;10(2):229-36.

PMID:
7838523
[PubMed - indexed for MEDLINE]
10.

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation.

Xu M, Sheppard KA, Peng CY, Yee AS, Piwnica-Worms H.

Mol Cell Biol. 1994 Dec;14(12):8420-31.

PMID:
7969176
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.

Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK, Rustum YM.

Exp Cell Res. 1999 Feb 25;247(1):189-99.

PMID:
10047461
[PubMed - indexed for MEDLINE]
12.

Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases.

Wohlschlegel JA, Dwyer BT, Takeda DY, Dutta A.

Mol Cell Biol. 2001 Aug;21(15):4868-74.

PMID:
11438644
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice.

Timchenko NA, Wilde M, Darlington GJ.

Mol Cell Biol. 1999 Apr;19(4):2936-45.

PMID:
10082561
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6.

Schulze-Gahmen U, Jung JU, Kim SH.

Structure. 1999 Mar 15;7(3):245-54.

PMID:
10368294
[PubMed - indexed for MEDLINE]
15.

Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A.

Zheleva DI, McInnes C, Gavine AL, Zhelev NZ, Fischer PM, Lane DP.

J Pept Res. 2002 Nov;60(5):257-70.

PMID:
12383116
[PubMed - indexed for MEDLINE]
16.

HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression.

Hall C, Nelson DM, Ye X, Baker K, DeCaprio JA, Seeholzer S, Lipinski M, Adams PD.

Mol Cell Biol. 2001 Mar;21(5):1854-65.

PMID:
11238922
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc.

Benaud CM, Dickson RB.

Oncogene. 2001 Jul 27;20(33):4554-67.

PMID:
11494151
[PubMed - indexed for MEDLINE]
Free Article
18.

Expression and activity of the retinoblastoma protein (pRB)-family proteins, p107 and p130, during L6 myoblast differentiation.

Kiess M, Gill RM, Hamel PA.

Cell Growth Differ. 1995 Oct;6(10):1287-98.

PMID:
8845306
[PubMed - indexed for MEDLINE]
Free Article
19.

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity.

Woo MS, Sánchez I, Dynlacht BD.

Mol Cell Biol. 1997 Jul;17(7):3566-79.

PMID:
9199292
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes.

Adams PD, Li X, Sellers WR, Baker KB, Leng X, Harper JW, Taya Y, Kaelin WG Jr.

Mol Cell Biol. 1999 Feb;19(2):1068-80.

PMID:
9891042
[PubMed - indexed for MEDLINE]
Free PMC Article

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