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Results: 1 to 20 of 407

1.

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation.

Ito A, Kawaguchi Y, Lai CH, Kovacs JJ, Higashimoto Y, Appella E, Yao TP.

EMBO J. 2002 Nov 15;21(22):6236-45.

PMID:
12426395
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins.

Kobet E, Zeng X, Zhu Y, Keller D, Lu H.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12547-52.

PMID:
11070080
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.

Knights CD, Liu Y, Appella E, Kulesz-Martin M.

J Biol Chem. 2003 Dec 26;278(52):52890-900. Epub 2003 Oct 10.

PMID:
14555661
[PubMed - indexed for MEDLINE]
Free Article
4.

SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription.

Pavithra L, Mukherjee S, Sreenath K, Kar S, Sakaguchi K, Roy S, Chattopadhyay S.

J Mol Biol. 2009 May 15;388(4):691-702. doi: 10.1016/j.jmb.2009.03.033. Epub 2009 Mar 19.

PMID:
19303885
[PubMed - indexed for MEDLINE]
5.

Acidic domain is indispensable for MDM2 to negatively regulate the acetylation of p53.

Wang Q, Yang Y, Wang L, Zhang PZ, Yu L.

Biochem Biophys Res Commun. 2008 Sep 26;374(3):437-41. doi: 10.1016/j.bbrc.2008.07.038. Epub 2008 Jul 16.

PMID:
18638452
[PubMed - indexed for MEDLINE]
6.

Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells.

Xu D, Wilson TJ, Chan D, De Luca E, Zhou J, Hertzog PJ, Kola I.

EMBO J. 2002 Aug 1;21(15):4081-93.

PMID:
12145208
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation.

Jin Y, Zeng SX, Dai MS, Yang XJ, Lu H.

J Biol Chem. 2002 Aug 23;277(34):30838-43. Epub 2002 Jun 14.

PMID:
12068014
[PubMed - indexed for MEDLINE]
Free Article
8.

Inhibition of p53 degradation by Mdm2 acetylation.

Wang X, Taplick J, Geva N, Oren M.

FEBS Lett. 2004 Mar 12;561(1-3):195-201.

PMID:
15013777
[PubMed - indexed for MEDLINE]
Free Article
9.

Dynamics of the p53 acetylation pathway.

Gu W, Luo J, Brooks CL, Nikolaev AY, Li M.

Novartis Found Symp. 2004;259:197-205; discussion 205-7, 223-5. Review.

PMID:
15171255
[PubMed - indexed for MEDLINE]
10.

Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1.

Higashitsuji H, Higashitsuji H, Masuda T, Liu Y, Itoh K, Fujita J.

J Biol Chem. 2007 May 4;282(18):13716-25. Epub 2007 Mar 12.

PMID:
17353187
[PubMed - indexed for MEDLINE]
Free Article
11.

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

Ito A, Lai CH, Zhao X, Saito S, Hamilton MH, Appella E, Yao TP.

EMBO J. 2001 Mar 15;20(6):1331-40.

PMID:
11250899
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu.

Goel A, Janknecht R.

Mol Cell Biol. 2003 Sep;23(17):6243-54.

PMID:
12917345
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Histone deacetylases specifically down-regulate p53-dependent gene activation.

Juan LJ, Shia WJ, Chen MH, Yang WM, Seto E, Lin YS, Wu CW.

J Biol Chem. 2000 Jul 7;275(27):20436-43.

PMID:
10777477
[PubMed - indexed for MEDLINE]
Free Article
15.

Acetylation of p53 inhibits its ubiquitination by Mdm2.

Li M, Luo J, Brooks CL, Gu W.

J Biol Chem. 2002 Dec 27;277(52):50607-11. Epub 2002 Nov 5.

PMID:
12421820
[PubMed - indexed for MEDLINE]
Free Article
16.

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

Le Cam L, Linares LK, Paul C, Julien E, Lacroix M, Hatchi E, Triboulet R, Bossis G, Shmueli A, Rodriguez MS, Coux O, Sardet C.

Cell. 2006 Nov 17;127(4):775-88.

PMID:
17110336
[PubMed - indexed for MEDLINE]
Free Article
17.

DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms.

Hsing A, Faller DV, Vaziri C.

J Biol Chem. 2000 Aug 25;275(34):26024-31.

PMID:
10856296
[PubMed - indexed for MEDLINE]
Free Article
18.

YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress.

Grönroos E, Terentiev AA, Punga T, Ericsson J.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12165-70. Epub 2004 Aug 4.

PMID:
15295102
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of transcription factor YY1 by acetylation and deacetylation.

Yao YL, Yang WM, Seto E.

Mol Cell Biol. 2001 Sep;21(17):5979-91.

PMID:
11486036
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts.

Gentiletti F, Mancini F, D'Angelo M, Sacchi A, Pontecorvi A, Jochemsen AG, Moretti F.

Oncogene. 2002 Jan 31;21(6):867-77.

PMID:
11840332
[PubMed - indexed for MEDLINE]
Free Article

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