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Results: 1 to 20 of 375

1.

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers.

Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, Hainaut P.

Oncogene. 2002 Oct 21;21(48):7435-51. Review.

PMID:
12379884
[PubMed - indexed for MEDLINE]
Free Article
3.

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.

Hainaut P, Pfeifer GP.

Carcinogenesis. 2001 Mar;22(3):367-74.

PMID:
11238174
[PubMed - indexed for MEDLINE]
Free Article
4.

Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.

Hussain SP, Amstad P, Raja K, Sawyer M, Hofseth L, Shields PG, Hewer A, Phillips DH, Ryberg D, Haugen A, Harris CC.

Cancer Res. 2001 Sep 1;61(17):6350-5.

PMID:
11522624
[PubMed - indexed for MEDLINE]
Free Article
5.

Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women.

Gealy R, Zhang L, Siegfried JM, Luketich JD, Keohavong P.

Cancer Epidemiol Biomarkers Prev. 1999 Apr;8(4 Pt 1):297-302. Erratum in: Cancer Epidemiol Biomarkers Prev 2001 Dec;10(12):1309.

PMID:
10207632
[PubMed - indexed for MEDLINE]
Free Article
6.

p53 and K-ras mutations in lung cancers from former and never-smoking women.

Vähäkangas KH, Bennett WP, Castrén K, Welsh JA, Khan MA, Blömeke B, Alavanja MC, Harris CC.

Cancer Res. 2001 Jun 1;61(11):4350-6.

PMID:
11389059
[PubMed - indexed for MEDLINE]
Free Article
7.

On the origin of p53 G:C --> T:A transversions in lung cancers.

Rodin SN, Rodin AS.

Mutat Res. 2002 Oct 31;508(1-2):1-19.

PMID:
12379456
[PubMed - indexed for MEDLINE]
8.

Comparison of p53 mutations between adenocarcinoma and squamous cell carcinoma of the lung: unique spectra involving G to A transitions and G to T transversions in both histologic types.

Gao WM, Mady HH, Yu GY, Siegfried JM, Luketich JD, Melhem MF, Keohavong P.

Lung Cancer. 2003 May;40(2):141-50.

PMID:
12711114
[PubMed - indexed for MEDLINE]
9.

Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.

Matter B, Wang G, Jones R, Tretyakova N.

Chem Res Toxicol. 2004 Jun;17(6):731-41.

PMID:
15206894
[PubMed - indexed for MEDLINE]
10.

On the origin of G --> T transversions in lung cancer.

Pfeifer GP, Hainaut P.

Mutat Res. 2003 May 15;526(1-2):39-43. Review.

PMID:
12714181
[PubMed - indexed for MEDLINE]
11.

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

Denissenko MF, Pao A, Tang M, Pfeifer GP.

Science. 1996 Oct 18;274(5286):430-2.

PMID:
8832894
[PubMed - indexed for MEDLINE]
12.

Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.

Tretyakova N, Matter B, Jones R, Shallop A.

Biochemistry. 2002 Jul 30;41(30):9535-44.

PMID:
12135376
[PubMed - indexed for MEDLINE]
13.

Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons.

Smith LE, Denissenko MF, Bennett WP, Li H, Amin S, Tang M, Pfeifer GP.

J Natl Cancer Inst. 2000 May 17;92(10):803-11.

PMID:
10814675
[PubMed - indexed for MEDLINE]
Free Article
14.

p53 mutational spectra and the role of methylated CpG sequences.

Pfeifer GP.

Mutat Res. 2000 May 30;450(1-2):155-66. Review.

PMID:
10838140
[PubMed - indexed for MEDLINE]
15.

hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer.

Hu YC, Ahrendt SA.

Int J Cancer. 2005 Apr 10;114(3):387-93.

PMID:
15551330
[PubMed - indexed for MEDLINE]
16.

Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells.

Feng Z, Hu W, Rom WN, Costa M, Tang MS.

Carcinogenesis. 2003 Apr;24(4):771-8.

PMID:
12727806
[PubMed - indexed for MEDLINE]
Free Article
17.

p53 mutations and exposure to environmental tobacco smoke in a multicenter study on lung cancer.

Husgafvel-Pursiainen K, Boffetta P, Kannio A, Nyberg F, Pershagen G, Mukeria A, Constantinescu V, Fortes C, Benhamou S.

Cancer Res. 2000 Jun 1;60(11):2906-11.

PMID:
10850436
[PubMed - indexed for MEDLINE]
Free Article
18.

Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?

Pfeifer GP, Denissenko MF.

Environ Mol Mutagen. 1998;31(3):197-205. Review.

PMID:
9585258
[PubMed - indexed for MEDLINE]
19.

Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients.

Hackman P, Hou SM, Nyberg F, Pershagen G, Lambert B.

Mutat Res. 2000 Jun 22;468(1):45-61.

PMID:
10863157
[PubMed - indexed for MEDLINE]
20.

Sequence distribution of acetaldehyde-derived N2-ethyl-dG adducts along duplex DNA.

Matter B, Guza R, Zhao J, Li ZZ, Jones R, Tretyakova N.

Chem Res Toxicol. 2007 Oct;20(10):1379-87. Epub 2007 Sep 15.

PMID:
17867647
[PubMed - indexed for MEDLINE]

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