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Results: 1 to 20 of 136

1.

Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria.

Jonassen T, Marbois BN, Faull KF, Clarke CF, Larsen PL.

J Biol Chem. 2002 Nov 22;277(47):45020-7. Epub 2002 Sep 24.

PMID:
12324451
[PubMed - indexed for MEDLINE]
Free Article
2.

Reproductive fitness and quinone content of Caenorhabditis elegans clk-1 mutants fed coenzyme Q isoforms of varying length.

Jonassen T, Davis DE, Larsen PL, Clarke CF.

J Biol Chem. 2003 Dec 19;278(51):51735-42. Epub 2003 Oct 6.

PMID:
14530273
[PubMed - indexed for MEDLINE]
Free Article
3.

A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants.

Jonassen T, Larsen PL, Clarke CF.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):421-6. Epub 2001 Jan 2.

PMID:
11136229
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.

Larsen PL, Clarke CF.

Science. 2002 Jan 4;295(5552):120-3.

PMID:
11778046
[PubMed - indexed for MEDLINE]
Free Article
5.

Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites.

Hihi AK, Gao Y, Hekimi S.

J Biol Chem. 2002 Jan 18;277(3):2202-6. Epub 2001 Nov 8.

PMID:
11706003
[PubMed - indexed for MEDLINE]
Free Article
6.

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.

Gomez F, Saiki R, Chin R, Srinivasan C, Clarke CF.

Gene. 2012 Sep 10;506(1):106-16. doi: 10.1016/j.gene.2012.06.023. Epub 2012 Jun 23.

PMID:
22735617
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.

Miyadera H, Amino H, Hiraishi A, Taka H, Murayama K, Miyoshi H, Sakamoto K, Ishii N, Hekimi S, Kita K.

J Biol Chem. 2001 Mar 16;276(11):7713-6. Epub 2001 Jan 17.

PMID:
11244089
[PubMed - indexed for MEDLINE]
Free Article
8.

Quinones in long-lived clk-1 mutants of Caenorhabditis elegans.

Miyadera H, Kano K, Miyoshi H, Ishii N, Hekimi S, Kita K.

FEBS Lett. 2002 Feb 13;512(1-3):33-7. Review.

PMID:
11852047
[PubMed - indexed for MEDLINE]
Free Article
9.

Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes.

Hihi AK, Kebir H, Hekimi S.

J Biol Chem. 2003 Oct 17;278(42):41013-8. Epub 2003 Jul 31.

PMID:
12893826
[PubMed - indexed for MEDLINE]
Free Article
10.

Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane of Caenorhabditis elegans.

Arroyo A, Santos-Ocaña C, Ruiz-Ferrer M, Padilla S, Gavilán A, Rodríguez-Aguilera JC, Navas P.

FEBS Lett. 2006 Mar 20;580(7):1740-6. Epub 2006 Feb 20.

PMID:
16504181
[PubMed - indexed for MEDLINE]
Free Article
11.

Molecular mechanism of maternal rescue in the clk-1 mutants of Caenorhabditis elegans.

Burgess J, Hihi AK, Benard CY, Branicky R, Hekimi S.

J Biol Chem. 2003 Dec 5;278(49):49555-62. Epub 2003 Sep 29.

PMID:
14517217
[PubMed - indexed for MEDLINE]
Free Article
12.

Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q.

Saiki R, Lunceford AL, Bixler T, Dang P, Lee W, Furukawa S, Larsen PL, Clarke CF.

Aging Cell. 2008 Jun;7(3):291-304. doi: 10.1111/j.1474-9726.2008.00378.x. Epub 2008 Feb 11.

PMID:
18267002
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development.

Gavilán A, Asencio C, Cabello J, Rodríguez-Aguilera JC, Schnabel R, Navas P.

Biofactors. 2005;25(1-4):21-9.

PMID:
16873927
[PubMed - indexed for MEDLINE]
14.

Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.

Padilla S, Jonassen T, Jiménez-Hidalgo MA, Fernández-Ayala DJ, López-Lluch G, Marbois B, Navas P, Clarke CF, Santos-Ocaña C.

J Biol Chem. 2004 Jun 18;279(25):25995-6004. Epub 2004 Apr 12.

PMID:
15078893
[PubMed - indexed for MEDLINE]
Free Article
15.

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans.

Felkai S, Ewbank JJ, Lemieux J, Labbé JC, Brown GG, Hekimi S.

EMBO J. 1999 Apr 1;18(7):1783-92.

PMID:
10202142
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Aging. Dietary advice on Q.

Tatar M, Rand DM.

Science. 2002 Jan 4;295(5552):54-5. No abstract available.

PMID:
11778030
[PubMed - indexed for MEDLINE]
17.

Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans.

Branicky R, Nguyen PA, Hekimi S.

Mol Cell Biol. 2006 May;26(10):3976-85.

PMID:
16648490
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis elegans.

Asencio C, Rodríguez-Aguilera JC, Ruiz-Ferrer M, Vela J, Navas P.

FASEB J. 2003 Jun;17(9):1135-7. Epub 2003 Apr 22.

PMID:
12709403
[PubMed - indexed for MEDLINE]
Free Article
19.

A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants.

Taub J, Lau JF, Ma C, Hahn JH, Hoque R, Rothblatt J, Chalfie M.

Nature. 1999 May 13;399(6732):162-6. Retraction in: Taub J, Lau JF, Ma C, Hahn JH, Hoque R, Rothblatt J, Chalfie M. Nature. 2003 Feb 13;421(6924):764.

PMID:
10335847
[PubMed - indexed for MEDLINE]
20.

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