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Results: 1 to 20 of 116

1.

Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus.

Karmakar P, Snowden CM, Ramsden DA, Bohr VA.

Nucleic Acids Res. 2002 Aug 15;30(16):3583-91.

PMID:
12177300
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.

Li B, Comai L.

J Biol Chem. 2001 Mar 30;276(13):9896-902. Epub 2001 Jan 4.

PMID:
11152456
[PubMed - indexed for MEDLINE]
Free Article
3.

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.

Opresko PL, Laine JP, Brosh RM Jr, Seidman MM, Bohr VA.

J Biol Chem. 2001 Nov 30;276(48):44677-87. Epub 2001 Sep 25.

PMID:
11572872
[PubMed - indexed for MEDLINE]
Free Article
4.

Functional interaction between Ku and the werner syndrome protein in DNA end processing.

Li B, Comai L.

J Biol Chem. 2000 Sep 15;275(37):28349-52. Erratum in: J Biol Chem 2000 Dec 15;275(50):39800.

PMID:
10880505
[PubMed - indexed for MEDLINE]
Free Article
5.

Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1.

Li B, Navarro S, Kasahara N, Comai L.

J Biol Chem. 2004 Apr 2;279(14):13659-67. Epub 2004 Jan 20.

PMID:
14734561
[PubMed - indexed for MEDLINE]
Free Article
6.

A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis.

Li B, Conway N, Navarro S, Comai L, Comai L.

Nucleic Acids Res. 2005 Dec 7;33(21):6861-7. Print 2005.

PMID:
16396834
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein.

Li B, Comai L.

Nucleic Acids Res. 2002 Sep 1;30(17):3653-61.

PMID:
12202749
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity.

Shen JC, Lao Y, Kamath-Loeb A, Wold MS, Loeb LA.

Mech Ageing Dev. 2003 Aug-Sep;124(8-9):921-30.

PMID:
14499497
[PubMed - indexed for MEDLINE]
9.

A central region of Ku80 mediates interaction with Ku70 in vivo.

Cary RB, Chen F, Shen Z, Chen DJ.

Nucleic Acids Res. 1998 Feb 15;26(4):974-9.

PMID:
9461456
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.

Karmakar P, Piotrowski J, Brosh RM Jr, Sommers JA, Miller SP, Cheng WH, Snowden CM, Ramsden DA, Bohr VA.

J Biol Chem. 2002 May 24;277(21):18291-302. Epub 2002 Mar 11.

PMID:
11889123
[PubMed - indexed for MEDLINE]
Free Article
11.

A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA.

Orren DK, Machwe A, Karmakar P, Piotrowski J, Cooper MP, Bohr VA.

Nucleic Acids Res. 2001 May 1;29(9):1926-34.

PMID:
11328876
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ku complex interacts with and stimulates the Werner protein.

Cooper MP, Machwe A, Orren DK, Brosh RM, Ramsden D, Bohr VA.

Genes Dev. 2000 Apr 15;14(8):907-12.

PMID:
10783163
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Werner syndrome protein: biochemical properties and functional interactions.

Bohr VA, Cooper M, Orren D, Machwe A, Piotrowski J, Sommers J, Karmakar P, Brosh R.

Exp Gerontol. 2000 Sep;35(6-7):695-702. Review.

PMID:
11053659
[PubMed - indexed for MEDLINE]
14.

Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.

Friedemann J, Grosse F, Zhang S.

J Biol Chem. 2005 Sep 2;280(35):31303-13. Epub 2005 Jul 1.

PMID:
15995249
[PubMed - indexed for MEDLINE]
Free Article
15.

Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases.

Doherty KM, Sommers JA, Gray MD, Lee JW, von Kobbe C, Thoma NH, Kureekattil RP, Kenny MK, Brosh RM Jr.

J Biol Chem. 2005 Aug 19;280(33):29494-505. Epub 2005 Jun 17.

PMID:
15965237
[PubMed - indexed for MEDLINE]
Free Article
16.

Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.

von Kobbe C, Harrigan JA, Schreiber V, Stiegler P, Piotrowski J, Dawut L, Bohr VA.

Nucleic Acids Res. 2004 Aug 3;32(13):4003-14. Print 2004.

PMID:
15292449
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Defining the minimal domain of Ku80 for interaction with Ku70.

Osipovich O, Durum SK, Muegge K.

J Biol Chem. 1997 Oct 24;272(43):27259-65.

PMID:
9341172
[PubMed - indexed for MEDLINE]
Free Article
18.

Werner syndrome protein contains three structure-specific DNA binding domains.

von Kobbe C, Thomä NH, Czyzewski BK, Pavletich NP, Bohr VA.

J Biol Chem. 2003 Dec 26;278(52):52997-3006. Epub 2003 Oct 8.

PMID:
14534320
[PubMed - indexed for MEDLINE]
Free Article
19.

DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA.

Machwe A, Xiao L, Theodore S, Orren DK.

J Biol Chem. 2002 Feb 8;277(6):4492-504. Epub 2001 Nov 20.

PMID:
11717307
[PubMed - indexed for MEDLINE]
Free Article
20.

Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.

Lee JW, Kusumoto R, Doherty KM, Lin GX, Zeng W, Cheng WH, von Kobbe C, Brosh RM Jr, Hu JS, Bohr VA.

J Biol Chem. 2005 Nov 25;280(47):39627-36. Epub 2005 Sep 7.

PMID:
16150736
[PubMed - indexed for MEDLINE]
Free Article

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