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Results: 1 to 20 of 773

1.

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G.

Cancer Res. 2002 Aug 1;62(15):4316-24.

PMID:
12154035
[PubMed - indexed for MEDLINE]
Free Article
2.

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.

Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH, Melillo G.

Cancer Res. 2005 Oct 1;65(19):9047-55.

PMID:
16204079
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.

Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL.

Mol Cell Biol. 1996 Sep;16(9):4604-13.

PMID:
8756616
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding.

Jones DT, Harris AL.

Mol Cancer Ther. 2006 Sep;5(9):2193-202.

PMID:
16985052
[PubMed - indexed for MEDLINE]
Free Article
6.

Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer.

Büchler P, Reber HA, Büchler M, Shrinkante S, Büchler MW, Friess H, Semenza GL, Hines OJ.

Pancreas. 2003 Jan;26(1):56-64.

PMID:
12499918
[PubMed - indexed for MEDLINE]
7.

Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cells.

Post DE, Van Meir EG.

Gene Ther. 2001 Dec;8(23):1801-7.

PMID:
11803400
[PubMed - indexed for MEDLINE]
Free Article
8.

Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide.

Kimura H, Weisz A, Kurashima Y, Hashimoto K, Ogura T, D'Acquisto F, Addeo R, Makuuchi M, Esumi H.

Blood. 2000 Jan 1;95(1):189-97.

PMID:
10607702
[PubMed - indexed for MEDLINE]
Free Article
9.

Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity.

Agani F, Semenza GL.

Mol Pharmacol. 1998 Nov;54(5):749-54.

PMID:
9804609
[PubMed - indexed for MEDLINE]
Free Article
11.

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.

Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG.

Cancer Res. 2005 Jan 15;65(2):605-12.

PMID:
15695405
[PubMed - indexed for MEDLINE]
Free Article
12.

Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 alpha and hypoxia-inducible factor-2 alpha in human bladder tumors and cell lines.

Jones A, Fujiyama C, Blanche C, Moore JW, Fuggle S, Cranston D, Bicknell R, Harris AL.

Clin Cancer Res. 2001 May;7(5):1263-72.

PMID:
11350893
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.

Görlach A, Diebold I, Schini-Kerth VB, Berchner-Pfannschmidt U, Roth U, Brandes RP, Kietzmann T, Busse R.

Circ Res. 2001 Jul 6;89(1):47-54.

PMID:
11440977
[PubMed - indexed for MEDLINE]
Free Article
16.

Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite.

Duyndam MC, Hulscher ST, van der Wall E, Pinedo HM, Boven E.

J Biol Chem. 2003 Feb 28;278(9):6885-95. Epub 2002 Dec 13.

PMID:
12482858
[PubMed - indexed for MEDLINE]
Free Article
17.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

PMID:
11431362
[PubMed - indexed for MEDLINE]
Free Article
18.

Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1.

Liu LX, Lu H, Luo Y, Date T, Belanger AJ, Vincent KA, Akita GY, Goldberg M, Cheng SH, Gregory RJ, Jiang C.

Biochem Biophys Res Commun. 2002 Mar 8;291(4):908-14.

PMID:
11866451
[PubMed - indexed for MEDLINE]
19.

Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors.

Yamakawa M, Liu LX, Date T, Belanger AJ, Vincent KA, Akita GY, Kuriyama T, Cheng SH, Gregory RJ, Jiang C.

Circ Res. 2003 Oct 3;93(7):664-73. Epub 2003 Sep 4.

PMID:
12958144
[PubMed - indexed for MEDLINE]
Free Article
20.

Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.

Damert A, Machein M, Breier G, Fujita MQ, Hanahan D, Risau W, Plate KH.

Cancer Res. 1997 Sep 1;57(17):3860-4.

PMID:
9288800
[PubMed - indexed for MEDLINE]
Free Article

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