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Items: 1 to 20 of 97

1.

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K.

Cell. 2002 Jul 26;110(2):177-89.

2.

Raptor, a binding partner of target of rapamycin.

Yonezawa K, Tokunaga C, Oshiro N, Yoshino K.

Biochem Biophys Res Commun. 2004 Jan 9;313(2):437-41. Review.

PMID:
14684181
3.

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif.

Nojima H, Tokunaga C, Eguchi S, Oshiro N, Hidayat S, Yoshino K, Hara K, Tanaka N, Avruch J, Yonezawa K.

J Biol Chem. 2003 May 2;278(18):15461-4. Epub 2003 Feb 25.

4.

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.

Schalm SS, Fingar DC, Sabatini DM, Blenis J.

Curr Biol. 2003 May 13;13(10):797-806.

5.

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.

Avruch J, Hara K, Lin Y, Liu M, Long X, Ortiz-Vega S, Yonezawa K.

Oncogene. 2006 Oct 16;25(48):6361-72. Review.

PMID:
17041622
6.
7.

Kinase activities associated with mTOR.

Yonezawa K, Yoshino KI, Tokunaga C, Hara K.

Curr Top Microbiol Immunol. 2004;279:271-82. Review.

PMID:
14560963
8.

Identification of a conserved motif required for mTOR signaling.

Schalm SS, Blenis J.

Curr Biol. 2002 Apr 16;12(8):632-9.

9.

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.

Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM.

Mol Cell. 2003 Apr;11(4):895-904.

10.

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.

Liu L, Li F, Cardelli JA, Martin KA, Blenis J, Huang S.

Oncogene. 2006 Nov 9;25(53):7029-40. Epub 2006 May 22.

PMID:
16715128
11.

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.

Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM.

Curr Biol. 2004 Jul 27;14(14):1296-302.

12.

Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function.

Oshiro N, Yoshino K, Hidayat S, Tokunaga C, Hara K, Eguchi S, Avruch J, Yonezawa K.

Genes Cells. 2004 Apr;9(4):359-66. Erratum in: Genes Cells. 2004 May;9(5):497.

13.

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.

Fingar DC, Salama S, Tsou C, Harlow E, Blenis J.

Genes Dev. 2002 Jun 15;16(12):1472-87.

14.

Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.

Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.

J Biol Chem. 2003 Jul 25;278(30):27772-80. Epub 2003 May 20.

15.

Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.

Wang L, Rhodes CJ, Lawrence JC Jr.

J Biol Chem. 2006 Aug 25;281(34):24293-303. Epub 2006 Jun 23.

16.

Raptor-rictor axis in TGFbeta-induced protein synthesis.

Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG.

Cell Signal. 2008 Feb;20(2):409-23. Epub 2007 Nov 7.

PMID:
18068336
17.

mTOR-mediated regulation of translation factors by amino acids.

Proud CG.

Biochem Biophys Res Commun. 2004 Jan 9;313(2):429-36. Review.

PMID:
14684180
18.

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM.

Cell. 2002 Jul 26;110(2):163-75.

19.

Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin.

Ohji G, Hidayat S, Nakashima A, Tokunaga C, Oshiro N, Yoshino K, Yokono K, Kikkawa U, Yonezawa K.

J Biochem. 2006 Jan;139(1):129-35.

PMID:
16428328
20.
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