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Results: 1 to 20 of 239

1.

Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel.

Mabuchi S, Ohmichi M, Kimura A, Hisamoto K, Hayakawa J, Nishio Y, Adachi K, Takahashi K, Arimoto-Ishida E, Nakatsuji Y, Tasaka K, Murata Y.

J Biol Chem. 2002 Sep 6;277(36):33490-500. Epub 2002 Jun 26.

PMID:
12087097
[PubMed - indexed for MEDLINE]
Free Article
2.

Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.

Hayakawa J, Ohmichi M, Kurachi H, Kanda Y, Hisamoto K, Nishio Y, Adachi K, Tasaka K, Kanzaki T, Murata Y.

Cancer Res. 2000 Nov 1;60(21):5988-94.

PMID:
11085518
[PubMed - indexed for MEDLINE]
Free Article
3.

HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway.

Kakazu A, Chandrasekher G, Bazan HE.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3485-92.

PMID:
15452053
[PubMed - indexed for MEDLINE]
Free Article
4.

Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.

Chandrasekher G, Sailaja D.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3577-88.

PMID:
15452065
[PubMed - indexed for MEDLINE]
Free Article
5.

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells.

Reusch HP, Zimmermann S, Schaefer M, Paul M, Moelling K.

J Biol Chem. 2001 Sep 7;276(36):33630-7. Epub 2001 Jul 6.

PMID:
11443134
[PubMed - indexed for MEDLINE]
Free Article
6.

Inhibition of inhibitor of nuclear factor-kappaB phosphorylation increases the efficacy of paclitaxel in in vitro and in vivo ovarian cancer models.

Mabuchi S, Ohmichi M, Nishio Y, Hayasaka T, Kimura A, Ohta T, Kawagoe J, Takahashi K, Yada-Hashimoto N, Seino-Noda H, Sakata M, Motoyama T, Kurachi H, Testa JR, Tasaka K, Murata Y.

Clin Cancer Res. 2004 Nov 15;10(22):7645-54.

PMID:
15569997
[PubMed - indexed for MEDLINE]
Free Article
7.

Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.

MacKeigan JP, Taxman DJ, Hunter D, Earp HS 3rd, Graves LM, Ting JP.

Clin Cancer Res. 2002 Jul;8(7):2091-9.

PMID:
12114408
[PubMed - indexed for MEDLINE]
Free Article
8.

Sublytic C5b-9-stimulated Schwann cell survival through PI 3-kinase-mediated phosphorylation of BAD.

Hila S, Soane L, Koski CL.

Glia. 2001 Oct;36(1):58-67.

PMID:
11571784
[PubMed - indexed for MEDLINE]
9.
10.

Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells.

Huang Y, Sheikh MS, Fornace AJ Jr, Holbrook NJ.

Oncogene. 1999 Jun 10;18(23):3431-9.

PMID:
10376521
[PubMed - indexed for MEDLINE]
Free Article
11.

p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association.

Jin S, Zhuo Y, Guo W, Field J.

J Biol Chem. 2005 Jul 1;280(26):24698-705. Epub 2005 Apr 22.

PMID:
15849194
[PubMed - indexed for MEDLINE]
Free Article
12.

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation.

Del Bufalo D, Di Castro V, Biroccio A, Varmi M, Salani D, RosanĂ² L, Trisciuoglio D, Spinella F, Bagnato A.

Mol Pharmacol. 2002 Mar;61(3):524-32.

PMID:
11854432
[PubMed - indexed for MEDLINE]
Free Article
13.

Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis.

Page C, Lin HJ, Jin Y, Castle VP, Nunez G, Huang M, Lin J.

Anticancer Res. 2000 Jan-Feb;20(1A):407-16.

PMID:
10769688
[PubMed - indexed for MEDLINE]
14.

Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt.

Fernando RI, Wimalasena J.

Mol Biol Cell. 2004 Jul;15(7):3266-84. Epub 2004 Apr 30.

PMID:
15121878
[PubMed - indexed for MEDLINE]
Free PMC Article
15.
16.

The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.

Lee YI, Kang-Park S, Do SI, Lee YI.

J Biol Chem. 2001 May 18;276(20):16969-77. Epub 2001 Mar 1.

PMID:
11278872
[PubMed - indexed for MEDLINE]
Free Article
17.

c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

Iijima Y, Laser M, Shiraishi H, Willey CD, Sundaravadivel B, Xu L, McDermott PJ, Kuppuswamy D.

J Biol Chem. 2002 Jun 21;277(25):23065-75. Epub 2002 Apr 8.

PMID:
11940578
[PubMed - indexed for MEDLINE]
Free Article
18.

The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel.

Mitsuuchi Y, Johnson SW, Selvakumaran M, Williams SJ, Hamilton TC, Testa JR.

Cancer Res. 2000 Oct 1;60(19):5390-4.

PMID:
11034077
[PubMed - indexed for MEDLINE]
Free Article
19.

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H.

J Biol Chem. 2001 Mar 30;276(13):9817-24. Epub 2001 Jan 3.

PMID:
11139588
[PubMed - indexed for MEDLINE]
Free Article
20.

Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes.

Kuwahara K, Saito Y, Kishimoto I, Miyamoto Y, Harada M, Ogawa E, Hamanaka I, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Nakao K.

J Mol Cell Cardiol. 2000 Aug;32(8):1385-94.

PMID:
10900165
[PubMed - indexed for MEDLINE]

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