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Items: 1 to 20 of 139

1.

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.

Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H.

Genes Dev. 2002 Jun 1;16(11):1345-55.

2.

Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.

Chan SL, Fu W, Zhang P, Cheng A, Lee J, Kokame K, Mattson MP.

J Biol Chem. 2004 Jul 2;279(27):28733-43. Epub 2004 Apr 21.

4.

Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies.

Yasuda S, Inoue K, Hirabayashi M, Higashiyama H, Yamamoto Y, Fuyuhiro H, Komure O, Tanaka F, Sobue G, Tsuchiya K, Hamada K, Sasaki H, Takeda K, Ichijo H, Kakizuka A.

Genes Cells. 1999 Dec;4(12):743-56.

5.

Expansion of the polyQ repeat in ataxin-2 alters its Golgi localization, disrupts the Golgi complex and causes cell death.

Huynh DP, Yang HT, Vakharia H, Nguyen D, Pulst SM.

Hum Mol Genet. 2003 Jul 1;12(13):1485-96.

6.

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation.

Kadowaki H, Nishitoh H, Urano F, Sadamitsu C, Matsuzawa A, Takeda K, Masutani H, Yodoi J, Urano Y, Nagano T, Ichijo H.

Cell Death Differ. 2005 Jan;12(1):19-24.

7.

Polyglutamine expansion, protein aggregation, proteasome activity, and neural survival.

Ding Q, Lewis JJ, Strum KM, Dimayuga E, Bruce-Keller AJ, Dunn JC, Keller JN.

J Biol Chem. 2002 Apr 19;277(16):13935-42. Epub 2002 Jan 8.

8.

ER stress is the initial response to polyglutamine toxicity in PC12 cells.

Nakayama H, Hamada M, Fujikake N, Nagai Y, Zhao J, Hatano O, Shimoke K, Isosaki M, Yoshizumi M, Ikeuchi T.

Biochem Biophys Res Commun. 2008 Dec 12;377(2):550-5. doi: 10.1016/j.bbrc.2008.10.006. Epub 2008 Oct 12.

PMID:
18854177
9.

Polyglutamine-mediated aggregation and cell death.

de Cristofaro T, Affaitati A, Feliciello A, Avvedimento EV, Varrone S.

Biochem Biophys Res Commun. 2000 Jun 16;272(3):816-21.

PMID:
10860836
11.

Humanin attenuates apoptosis induced by DRPLA proteins with expanded polyglutamine stretches.

Kariya S, Hirano M, Nagai Y, Furiya Y, Fujikake N, Toda T, Ueno S.

J Mol Neurosci. 2005;25(2):165-9.

PMID:
15784964
12.
13.

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response.

Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W.

J Biol Chem. 2008 May 2;283(18):11905-12. doi: 10.1074/jbc.M710557200. Epub 2008 Feb 15.

14.

Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation.

Hung CC, Ichimura T, Stevens JL, Bonventre JV.

J Biol Chem. 2003 Aug 1;278(31):29317-26. Epub 2003 May 8.

15.

A kinase-independent function of Ask1 in caspase-independent cell death.

Charette SJ, Lambert H, Landry J.

J Biol Chem. 2001 Sep 28;276(39):36071-4. Epub 2001 Aug 7.

16.

The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases.

Sekine Y, Takeda K, Ichijo H.

Curr Mol Med. 2006 Feb;6(1):87-97. Review.

PMID:
16472116
18.

Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation.

Jakobi R, McCarthy CC, Koeppel MA, Stringer DK.

J Biol Chem. 2003 Oct 3;278(40):38675-85. Epub 2003 Jul 9.

19.

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

Tsai YC, Fishman PS, Thakor NV, Oyler GA.

J Biol Chem. 2003 Jun 13;278(24):22044-55. Epub 2003 Apr 3.

20.

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.

Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW, Lee ST, Kim M, Ryu H, Jung YK.

Hum Mol Genet. 2012 Jan 1;21(1):101-14. doi: 10.1093/hmg/ddr445. Epub 2011 Sep 27.

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