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Results: 1 to 20 of 136

1.

Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-alpha-converting enzyme.

Lee MH, Verma V, Maskos K, Nath D, Knäuper V, Dodds P, Amour A, Murphy G.

Biochem J. 2002 May 15;364(Pt 1):227-34.

PMID:
11988096
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tailoring tissue inhibitor of metalloproteinases-3 to overcome the weakening effects of the cysteine-rich domains of tumour necrosis factor-alpha converting enzyme.

Lee MH, Dodds P, Verma V, Maskos K, Knäuper V, Murphy G.

Biochem J. 2003 Apr 15;371(Pt 2):369-76.

PMID:
12556225
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.

Lee MH, Rapti M, Murphy G.

J Biol Chem. 2004 Oct 22;279(43):45121-9. Epub 2004 Aug 12.

PMID:
15308656
[PubMed - indexed for MEDLINE]
Free Article
5.

Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase.

Lee MH, Knäuper V, Becherer JD, Murphy G.

Biochem Biophys Res Commun. 2001 Jan 26;280(3):945-50.

PMID:
11162616
[PubMed - indexed for MEDLINE]
6.

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3.

Lee MH, Verma V, Maskos K, Becherer JD, Knäuper V, Dodds P, Amour A, Murphy G.

FEBS Lett. 2002 Jun 5;520(1-3):102-6.

PMID:
12044879
[PubMed - indexed for MEDLINE]
Free Article
7.

Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-alpha-converting enzyme.

Wei S, Kashiwagi M, Kota S, Xie Z, Nagase H, Brew K.

J Biol Chem. 2005 Sep 23;280(38):32877-82. Epub 2005 Aug 3.

PMID:
16079149
[PubMed - indexed for MEDLINE]
Free Article
8.

Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition.

Lee MH, Rapti M, Knaüper V, Murphy G.

J Biol Chem. 2004 Apr 23;279(17):17562-9. Epub 2004 Jan 20.

PMID:
14734567
[PubMed - indexed for MEDLINE]
Free Article
9.

Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.

Wisniewska M, Goettig P, Maskos K, Belouski E, Winters D, Hecht R, Black R, Bode W.

J Mol Biol. 2008 Sep 19;381(5):1307-19. doi: 10.1016/j.jmb.2008.06.088. Epub 2008 Jul 7.

PMID:
18638486
[PubMed - indexed for MEDLINE]
10.

Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain.

Gonzales PE, Solomon A, Miller AB, Leesnitzer MA, Sagi I, Milla ME.

J Biol Chem. 2004 Jul 23;279(30):31638-45. Epub 2004 Apr 20.

PMID:
15100227
[PubMed - indexed for MEDLINE]
Free Article
11.

Tumor necrosis factor-alpha-converting enzyme controls surface expression of c-Kit and survival of embryonic stem cell-derived mast cells.

Cruz AC, Frank BT, Edwards ST, Dazin PF, Peschon JJ, Fang KC.

J Biol Chem. 2004 Feb 13;279(7):5612-20. Epub 2003 Nov 18.

PMID:
14625290
[PubMed - indexed for MEDLINE]
Free Article
13.

Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).

Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.

Biochem J. 2010 Aug 15;430(1):79-86. doi: 10.1042/BJ20100649.

PMID:
20533908
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.

Amour A, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Stephens PE, Shelley C, Hutton M, Knäuper V, Docherty AJ, Murphy G.

FEBS Lett. 1998 Sep 11;435(1):39-44.

PMID:
9755855
[PubMed - indexed for MEDLINE]
Free Article
15.

Multiple metalloproteinases process protransforming growth factor-alpha (proTGF-alpha).

Hinkle CL, Mohan MJ, Lin P, Yeung N, Rasmussen F, Milla ME, Moss ML.

Biochemistry. 2003 Feb 25;42(7):2127-36.

PMID:
12590602
[PubMed - indexed for MEDLINE]
16.

Proteasome inhibition activates the transport and the ectodomain shedding of TNF-alpha receptors in human endothelial cells.

Peiretti F, Canault M, Bernot D, Bonardo B, Deprez-Beauclair P, Juhan-Vague I, Nalbone G.

J Cell Sci. 2005 Mar 1;118(Pt 5):1061-70.

PMID:
15731011
[PubMed - indexed for MEDLINE]
Free Article
17.

TIMP-3 ameliorates hepatic ischemia/reperfusion injury through inhibition of tumor necrosis factor-alpha-converting enzyme activity in rats.

Tang ZY, Loss G, Carmody I, Cohen AJ.

Transplantation. 2006 Dec 15;82(11):1518-23.

PMID:
17164725
[PubMed - indexed for MEDLINE]
18.

Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1).

Tsakadze NL, Sithu SD, Sen U, English WR, Murphy G, D'Souza SE.

J Biol Chem. 2006 Feb 10;281(6):3157-64. Epub 2005 Dec 6.

PMID:
16332693
[PubMed - indexed for MEDLINE]
Free Article
19.

Processing of tumor necrosis factor by the membrane-bound TNF-alpha-converting enzyme, but not its truncated soluble form.

Itai T, Tanaka M, Nagata S.

Eur J Biochem. 2001 Apr;268(7):2074-82.

PMID:
11277930
[PubMed - indexed for MEDLINE]
Free Article
20.

Different domain interactions are involved in the binding of tissue inhibitors of metalloproteinases to stromelysin-1 and gelatinase A.

Nguyen Q, Willenbrock F, Cockett MI, O'Shea M, Docherty AJ, Murphy G.

Biochemistry. 1994 Mar 1;33(8):2089-95.

PMID:
8117665
[PubMed - indexed for MEDLINE]

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