Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 127

1.

Synergism of aminobisphosphonates and farnesyl transferase inhibitors on tumor metastasis.

Andela VB, Rosenblatt JD, Schwarz EM, Puzas EJ, O'Keefe RJ, Rosier RN.

Clin Orthop Relat Res. 2002 Apr;(397):228-39.

PMID:
11953614
2.

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.

Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.

Cancer Res. 2001 Dec 15;61(24):8758-68.

3.

Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.

End DW, Smets G, Todd AV, Applegate TL, Fuery CJ, Angibaud P, Venet M, Sanz G, Poignet H, Skrzat S, Devine A, Wouters W, Bowden C.

Cancer Res. 2001 Jan 1;61(1):131-7.

4.

Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.

Kelland LR, Smith V, Valenti M, Patterson L, Clarke PA, Detre S, End D, Howes AJ, Dowsett M, Workman P, Johnston SR.

Clin Cancer Res. 2001 Nov;7(11):3544-50.

5.

Antitumor activity of ER-51785, a new peptidomimetic inhibitor of farnesyl transferase: synergistic effect in combination with paclitaxel.

Nakamura K, Yamaguchi A, Namiki M, Ishihara H, Nagasu T, Kowalczyk JJ, Garcia AM, Lewis MD, Yoshimatsu K.

Oncol Res. 2001;12(11-12):477-84.

PMID:
11939411
6.

The mevalonate synthesis pathway as a therapeutic target in cancer.

Andela VB, Pirri M, Schwarz EM, Puzas EJ, O'Keefe RJ, Rosenblatt JD, Rosier RN.

Clin Orthop Relat Res. 2003 Oct;(415 Suppl):S59-66. Review.

PMID:
14600593
7.

The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.

Caraglia M, D'Alessandro AM, Marra M, Giuberti G, Vitale G, Viscomi C, Colao A, Prete SD, Tagliaferri P, Tassone P, Budillon A, Venuta S, Abbruzzese A.

Oncogene. 2004 Sep 9;23(41):6900-13.

PMID:
15286715
8.
9.

Farnesyl transferase inhibitors in the treatment of breast cancer.

Kelland LR.

Expert Opin Investig Drugs. 2003 Mar;12(3):413-21. Review.

PMID:
12605564
10.

Protein prenyl transferase activities of Plasmodium falciparum.

Chakrabarti D, Azam T, DelVecchio C, Qiu L, Park YI, Allen CM.

Mol Biochem Parasitol. 1998 Aug 1;94(2):175-84.

PMID:
9747968
11.

Farnesyl transferase inhibitors as anticancer agents.

Haluska P, Dy GK, Adjei AA.

Eur J Cancer. 2002 Sep;38(13):1685-700. Review.

PMID:
12175684
12.
13.

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase.

Bergstrom JD, Bostedor RG, Masarachia PJ, Reszka AA, Rodan G.

Arch Biochem Biophys. 2000 Jan 1;373(1):231-41.

PMID:
10620343
14.

Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery.

Venet M, End D, Angibaud P.

Curr Top Med Chem. 2003;3(10):1095-102. Review.

PMID:
12769710
15.

Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.

Le Gouill S, Pellat-Deceunynck C, Harousseau JL, Rapp MJ, Robillard N, Bataille R, Amiot M.

Leukemia. 2002 Sep;16(9):1664-7.

16.
17.

Anti-tumor activity of the farnesyl-protein transferase inhibitors arteminolides, isolated from Artemisa.

Lee SH, Lee MY, Kang HM, Han DC, Son KH, Yang DC, Sung ND, Lee CW, Kim HM, Kwon BM.

Bioorg Med Chem. 2003 Oct 15;11(21):4545-9.

PMID:
14527550
18.

Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies.

Cortes J, Albitar M, Thomas D, Giles F, Kurzrock R, Thibault A, Rackoff W, Koller C, O'Brien S, Garcia-Manero G, Talpaz M, Kantarjian H.

Blood. 2003 Mar 1;101(5):1692-7. Epub 2002 Oct 31.

19.
20.

Using inhibitors of prenylation to block localization and transforming activity.

Berzat AC, Brady DC, Fiordalisi JJ, Cox AD.

Methods Enzymol. 2006;407:575-97.

PMID:
16757354
Items per page

Supplemental Content

Write to the Help Desk