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Results: 1 to 20 of 136

1.

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.

Yazdi PT, Wang Y, Zhao S, Patel N, Lee EY, Qin J.

Genes Dev. 2002 Mar 1;16(5):571-82.

PMID:
11877377
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.

Kim ST, Xu B, Kastan MB.

Genes Dev. 2002 Mar 1;16(5):560-70.

PMID:
11877376
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.

Lee JH, Xu B, Lee CH, Ahn JY, Song MS, Lee H, Canman CE, Lee JS, Kastan MB, Lim DS.

Mol Cancer Res. 2003 Jul;1(9):674-81.

PMID:
12861053
[PubMed - indexed for MEDLINE]
Free Article
4.

Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3.

Luo H, Li Y, Mu JJ, Zhang J, Tonaka T, Hamamori Y, Jung SY, Wang Y, Qin J.

J Biol Chem. 2008 Jul 11;283(28):19176-83. doi: 10.1074/jbc.M802299200. Epub 2008 Apr 28.

PMID:
18442975
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The mismatch repair system is required for S-phase checkpoint activation.

Brown KD, Rathi A, Kamath R, Beardsley DI, Zhan Q, Mannino JL, Baskaran R.

Nat Genet. 2003 Jan;33(1):80-4. Epub 2002 Nov 25.

PMID:
12447371
[PubMed - indexed for MEDLINE]
6.

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB.

Genes Dev. 2004 Jun 15;18(12):1423-38. Epub 2004 Jun 2.

PMID:
15175241
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.

Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K.

Radiat Res. 2008 Sep;170(3):345-52. doi: 10.1667/RR1357.1.

PMID:
18763866
[PubMed - indexed for MEDLINE]
8.

Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.

Horton JK, Stefanick DF, Zeng JY, Carrozza MJ, Wilson SH.

DNA Repair (Amst). 2011 Feb 7;10(2):225-34. doi: 10.1016/j.dnarep.2010.11.003. Epub 2010 Dec 3.

PMID:
21130714
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.

Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH.

Nature. 2007 May 10;447(7141):218-21. Epub 2007 Apr 11.

PMID:
17429352
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.

Lim DS, Kim ST, Xu B, Maser RS, Lin J, Petrini JH, Kastan MB.

Nature. 2000 Apr 6;404(6778):613-7.

PMID:
10766245
[PubMed - indexed for MEDLINE]
11.

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.

Girard PM, Riballo E, Begg AC, Waugh A, Jeggo PA.

Oncogene. 2002 Jun 20;21(27):4191-9.

PMID:
12082606
[PubMed - indexed for MEDLINE]
Free Article
12.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22.

PMID:
15784679
[PubMed - indexed for MEDLINE]
Free Article
13.

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.

Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J.

Oncogene. 2004 Apr 15;23(17):3122-7.

PMID:
15048089
[PubMed - indexed for MEDLINE]
14.

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways.

Falck J, Petrini JH, Williams BR, Lukas J, Bartek J.

Nat Genet. 2002 Mar;30(3):290-4. Epub 2002 Feb 19.

PMID:
11850621
[PubMed - indexed for MEDLINE]
15.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

PMID:
12588868
[PubMed - indexed for MEDLINE]
Free Article
16.

MDC1 is required for the intra-S-phase DNA damage checkpoint.

Goldberg M, Stucki M, Falck J, D'Amours D, Rahman D, Pappin D, Bartek J, Jackson SP.

Nature. 2003 Feb 27;421(6926):952-6.

PMID:
12607003
[PubMed - indexed for MEDLINE]
17.

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.

Krause DR, Jonnalagadda JC, Gatei MH, Sillje HH, Zhou BB, Nigg EA, Khanna K.

Oncogene. 2003 Sep 4;22(38):5927-37.

PMID:
12955071
[PubMed - indexed for MEDLINE]
18.

Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.

Taylor AM, Groom A, Byrd PJ.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1219-25. Review.

PMID:
15279810
[PubMed - indexed for MEDLINE]
19.

Chk2 activation dependence on Nbs1 after DNA damage.

Buscemi G, Savio C, Zannini L, Miccichè F, Masnada D, Nakanishi M, Tauchi H, Komatsu K, Mizutani S, Khanna K, Chen P, Concannon P, Chessa L, Delia D.

Mol Cell Biol. 2001 Aug;21(15):5214-22.

PMID:
11438675
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ATMIN defines an NBS1-independent pathway of ATM signalling.

Kanu N, Behrens A.

EMBO J. 2007 Jun 20;26(12):2933-41. Epub 2007 May 24.

PMID:
17525732
[PubMed - indexed for MEDLINE]
Free PMC Article

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