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Results: 1 to 20 of 180

1.

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.

Xu B, Kim ST, Lim DS, Kastan MB.

Mol Cell Biol. 2002 Feb;22(4):1049-59.

PMID:
11809797
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.

Xu B, Kim St, Kastan MB.

Mol Cell Biol. 2001 May;21(10):3445-50.

PMID:
11313470
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

PMID:
12588868
[PubMed - indexed for MEDLINE]
Free Article
4.

An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells.

Krempler A, Deckbar D, Jeggo PA, Löbrich M.

Cell Cycle. 2007 Jul 15;6(14):1682-6. Epub 2007 May 21. Review.

PMID:
17637566
[PubMed - indexed for MEDLINE]
Free Article
5.

Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation.

Xu B, O'Donnell AH, Kim ST, Kastan MB.

Cancer Res. 2002 Aug 15;62(16):4588-91.

PMID:
12183412
[PubMed - indexed for MEDLINE]
Free Article
6.

Three independent mechanisms for arrest in G2 after ionizing radiation.

Landsverk KS, Patzke S, Rein ID, Stokke C, Lyng H, De Angelis PM, Stokke T.

Cell Cycle. 2011 Mar 1;10(5):819-29. Epub 2011 Mar 1.

PMID:
21325885
[PubMed - indexed for MEDLINE]
Free Article
7.

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.

Girard PM, Riballo E, Begg AC, Waugh A, Jeggo PA.

Oncogene. 2002 Jun 20;21(27):4191-9.

PMID:
12082606
[PubMed - indexed for MEDLINE]
Free Article
9.

The limitations of the G1-S checkpoint.

Deckbar D, Stiff T, Koch B, Reis C, Löbrich M, Jeggo PA.

Cancer Res. 2010 Jun 1;70(11):4412-21. doi: 10.1158/0008-5472.CAN-09-3198. Epub 2010 May 11.

PMID:
20460507
[PubMed - indexed for MEDLINE]
Free Article
10.

Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells.

Momcilović O, Choi S, Varum S, Bakkenist C, Schatten G, Navara C.

Stem Cells. 2009 Aug;27(8):1822-35. doi: 10.1002/stem.123.

PMID:
19544417
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity.

Krueger SA, Wilson GD, Piasentin E, Joiner MC, Marples B.

Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1509-17. doi: 10.1016/j.ijrobp.2010.01.028.

PMID:
20637979
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.

Lee JH, Xu B, Lee CH, Ahn JY, Song MS, Lee H, Canman CE, Lee JS, Kastan MB, Lim DS.

Mol Cancer Res. 2003 Jul;1(9):674-81.

PMID:
12861053
[PubMed - indexed for MEDLINE]
Free Article
13.

Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity.

Krueger SA, Collis SJ, Joiner MC, Wilson GD, Marples B.

Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1262-71.

PMID:
17967316
[PubMed - indexed for MEDLINE]
14.

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

Stiff T, Cerosaletti K, Concannon P, O'Driscoll M, Jeggo PA.

Hum Mol Genet. 2008 Oct 15;17(20):3247-53. doi: 10.1093/hmg/ddn220. Epub 2008 Jul 28.

PMID:
18664457
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Ionizing radiation activates the ATM kinase throughout the cell cycle.

Pandita TK, Lieberman HB, Lim DS, Dhar S, Zheng W, Taya Y, Kastan MB.

Oncogene. 2000 Mar 9;19(11):1386-91.

PMID:
10723129
[PubMed - indexed for MEDLINE]
Free Article
16.

Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.

Siu WY, Lau A, Arooz T, Chow JP, Ho HT, Poon RY.

Mol Cancer Ther. 2004 May;3(5):621-32.

PMID:
15141020
[PubMed - indexed for MEDLINE]
Free Article
17.

Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.

Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ.

Cancer Res. 2001 Nov 15;61(22):8290-7.

PMID:
11719462
[PubMed - indexed for MEDLINE]
Free Article
18.

Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.

Yong W, Bao S, Chen H, Li D, Sánchez ER, Shou W.

J Biol Chem. 2007 May 18;282(20):14690-4. Epub 2007 Mar 21.

PMID:
17376776
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3.

Luo H, Li Y, Mu JJ, Zhang J, Tonaka T, Hamamori Y, Jung SY, Wang Y, Qin J.

J Biol Chem. 2008 Jul 11;283(28):19176-83. doi: 10.1074/jbc.M802299200. Epub 2008 Apr 28.

PMID:
18442975
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.

Wang X, Khadpe J, Hu B, Iliakis G, Wang Y.

J Biol Chem. 2003 Aug 15;278(33):30869-74. Epub 2003 Jun 4.

PMID:
12791699
[PubMed - indexed for MEDLINE]
Free Article

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