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Results: 1 to 20 of 71

1.

Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth.

Powers C, Aigner A, Stoica GE, McDonnell K, Wellstein A.

J Biol Chem. 2002 Apr 19;277(16):14153-8. Epub 2002 Jan 23.

PMID:
11809760
[PubMed - indexed for MEDLINE]
Free Article
2.

Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK.

Grzelinski M, Steinberg F, Martens T, Czubayko F, Lamszus K, Aigner A.

Neoplasia. 2009 Feb;11(2):145-56.

PMID:
19177199
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Anti-apoptotic signaling of pleiotrophin through its receptor, anaplastic lymphoma kinase.

Bowden ET, Stoica GE, Wellstein A.

J Biol Chem. 2002 Sep 27;277(39):35862-8. Epub 2002 Jul 9.

PMID:
12107166
[PubMed - indexed for MEDLINE]
Free Article
4.

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types.

Stoica GE, Kuo A, Powers C, Bowden ET, Sale EB, Riegel AT, Wellstein A.

J Biol Chem. 2002 Sep 27;277(39):35990-8. Epub 2002 Jul 16.

PMID:
12122009
[PubMed - indexed for MEDLINE]
Free Article
5.

Ribozyme-targeting reveals the rate-limiting role of pleiotrophin in glioblastoma.

Grzelinski M, Bader N, Czubayko F, Aigner A.

Int J Cancer. 2005 Dec 20;117(6):942-51.

PMID:
15986444
[PubMed - indexed for MEDLINE]
6.

In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)?

Mathivet T, Mazot P, Vigny M.

Cell Signal. 2007 Dec;19(12):2434-43. Epub 2007 Jul 25.

PMID:
17904822
[PubMed - indexed for MEDLINE]
7.

Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin.

Stoica GE, Kuo A, Aigner A, Sunitha I, Souttou B, Malerczyk C, Caughey DJ, Wen D, Karavanov A, Riegel AT, Wellstein A.

J Biol Chem. 2001 May 18;276(20):16772-9. Epub 2001 Feb 8.

PMID:
11278720
[PubMed - indexed for MEDLINE]
Free Article
8.

Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor.

Stylianou DC, Auf der Maur A, Kodack DP, Henke RT, Hohn S, Toretsky JA, Riegel AT, Wellstein A.

Oncogene. 2009 Sep 17;28(37):3296-306. doi: 10.1038/onc.2009.184. Epub 2009 Jul 27.

PMID:
19633684
[PubMed - indexed for MEDLINE]
9.

Differential induction of glioblastoma migration and growth by two forms of pleiotrophin.

Lu KV, Jong KA, Kim GY, Singh J, Dia EQ, Yoshimoto K, Wang MY, Cloughesy TF, Nelson SF, Mischel PS.

J Biol Chem. 2005 Jul 22;280(29):26953-64. Epub 2005 May 20.

PMID:
15908427
[PubMed - indexed for MEDLINE]
Free Article
10.

Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation.

Perez-Pinera P, Zhang W, Chang Y, Vega JA, Deuel TF.

J Biol Chem. 2007 Sep 28;282(39):28683-90. Epub 2007 Aug 6.

PMID:
17681947
[PubMed - indexed for MEDLINE]
Free Article
11.

The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Haruta R, Nasu-Nishimura Y, Taniue K, Katou Y, Shirahige K, Todo T, Ino Y, Mukasa A, Saito N, Matsui M, Takahashi R, Hoshino-Okubo A, Sugano H, Manabe E, Funato K, Akiyama T.

Oncogene. 2014 Apr 24;33(17):2236-44. doi: 10.1038/onc.2013.168. Epub 2013 May 20.

PMID:
23686309
[PubMed - indexed for MEDLINE]
12.

Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J.

J Biol Chem. 2003 Aug 8;278(32):30028-36. Epub 2003 May 14.

PMID:
12748172
[PubMed - indexed for MEDLINE]
Free Article
13.

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.

Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J.

J Natl Cancer Inst. 1999 Sep 15;91(18):1548-56. Erratum in: J Natl Cancer Inst 2000 Jan 5;92(1):78.

PMID:
10491431
[PubMed - indexed for MEDLINE]
Free Article
14.

Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.

Kuo AH, Stoica GE, Riegel AT, Wellstein A.

Oncogene. 2007 Feb 8;26(6):859-69. Epub 2006 Jul 31.

PMID:
16878150
[PubMed - indexed for MEDLINE]
15.

Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3beta/beta-catenin signaling in developing mouse neurons.

Yanagisawa H, Komuta Y, Kawano H, Toyoda M, Sango K.

Neurosci Res. 2010 Jan;66(1):111-6. doi: 10.1016/j.neures.2009.10.002. Epub 2009 Oct 13.

PMID:
19833155
[PubMed - indexed for MEDLINE]
16.

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.

Oncogene. 2007 Aug 16;26(38):5606-14. Epub 2007 Mar 12.

PMID:
17353907
[PubMed - indexed for MEDLINE]
17.

Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy.

Li R, Morris SW.

Med Res Rev. 2008 May;28(3):372-412. Review.

PMID:
17694547
[PubMed - indexed for MEDLINE]
18.

Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer.

Perez-Pinera P, Chang Y, Astudillo A, Mortimer J, Deuel TF.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):399-403. Epub 2007 Apr 30.

PMID:
17490616
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin.

Moog-Lutz C, Degoutin J, Gouzi JY, Frobert Y, Brunet-de Carvalho N, Bureau J, Créminon C, Vigny M.

J Biol Chem. 2005 Jul 15;280(28):26039-48. Epub 2005 May 10.

PMID:
15886198
[PubMed - indexed for MEDLINE]
Free Article
20.

The emerging normal and disease-related roles of anaplastic lymphoma kinase.

Pulford K, Lamant L, Espinos E, Jiang Q, Xue L, Turturro F, Delsol G, Morris SW.

Cell Mol Life Sci. 2004 Dec;61(23):2939-53. Review.

PMID:
15583856
[PubMed - indexed for MEDLINE]

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