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Results: 1 to 20 of 95

1.

Probing the open state of cytochrome P450cam with ruthenium-linker substrates.

Dunn AR, Dmochowski IJ, Bilwes AM, Gray HB, Crane BR.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12420-5. Epub 2001 Oct 16.

PMID:
11606730
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural evidence for a functionally relevant second camphor binding site in P450cam: model for substrate entry into a P450 active site.

Yao H, McCullough CR, Costache AD, Pullela PK, Sem DS.

Proteins. 2007 Oct 1;69(1):125-38.

PMID:
17598143
[PubMed - indexed for MEDLINE]
3.
4.

Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.

Prasad S, Mitra S.

Biochemistry. 2002 Dec 10;41(49):14499-508.

PMID:
12463748
[PubMed - indexed for MEDLINE]
5.

Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires.

Hays AM, Dunn AR, Chiu R, Gray HB, Stout CD, Goodin DB.

J Mol Biol. 2004 Nov 19;344(2):455-69.

PMID:
15522298
[PubMed - indexed for MEDLINE]
6.

Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel.

Lee YT, Glazer EC, Wilson RF, Stout CD, Goodin DB.

Biochemistry. 2011 Feb 8;50(5):693-703. doi: 10.1021/bi101726d. Epub 2011 Jan 11.

PMID:
21171581
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

P450cam visits an open conformation in the absence of substrate.

Lee YT, Wilson RF, Rupniewski I, Goodin DB.

Biochemistry. 2010 Apr 27;49(16):3412-9. doi: 10.1021/bi100183g.

PMID:
20297780
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

The structure of CYP101D2 unveils a potential path for substrate entry into the active site.

Yang W, Bell SG, Wang H, Zhou W, Bartlam M, Wong LL, Rao Z.

Biochem J. 2011 Jan 1;433(1):85-93. doi: 10.1042/BJ20101017.

PMID:
20950270
[PubMed - indexed for MEDLINE]
Free Article
10.

Specific and non-specific effects of potassium cations on substrate-protein interactions in cytochromes P450cam and P450lin.

Deprez E, Gill E, Helms V, Wade RC, Hui Bon Hoa G.

J Inorg Biochem. 2002 Sep 20;91(4):597-606.

PMID:
12237225
[PubMed - indexed for MEDLINE]
11.

The catalytic pathway of cytochrome p450cam at atomic resolution.

Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG.

Science. 2000 Mar 3;287(5458):1615-22.

PMID:
10698731
[PubMed - indexed for MEDLINE]
Free Article
12.

Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam.

Bell SG, Chen X, Sowden RJ, Xu F, Williams JN, Wong LL, Rao Z.

J Am Chem Soc. 2003 Jan 22;125(3):705-14.

PMID:
12526670
[PubMed - indexed for MEDLINE]
13.

Putidaredoxin-cytochrome P450cam interaction.

Shimada H, Nagano S, Hori H, Ishimura Y.

J Inorg Biochem. 2001 Feb;83(4):255-60. Review.

PMID:
11293545
[PubMed - indexed for MEDLINE]
14.

Enantiomeric discrimination of Ru-substrates by cytochrome P450cam.

Dmochowski IJ, Winkler JR, Gray HB.

J Inorg Biochem. 2000 Aug 31;81(3):221-8.

PMID:
11051567
[PubMed - indexed for MEDLINE]
15.

Engineering substrate recognition in catalysis by cytochrome P450cam.

Bell SG, Chen X, Xu F, Rao Z, Wong LL.

Biochem Soc Trans. 2003 Jun;31(Pt 3):558-62. Review.

PMID:
12773156
[PubMed - indexed for MEDLINE]
16.

X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center.

Hishiki T, Shimada H, Nagano S, Egawa T, Kanamori Y, Makino R, Park SY, Adachi S, Shiro Y, Ishimura Y.

J Biochem. 2000 Dec;128(6):965-74.

PMID:
11098139
[PubMed - indexed for MEDLINE]
Free Article
17.

Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate.

Stoll S, Lee YT, Zhang M, Wilson RF, Britt RD, Goodin DB.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):12888-93. doi: 10.1073/pnas.1207123109. Epub 2012 Jul 23.

PMID:
22826259
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Substrate binding induces structural changes in cytochrome P450cam.

Sakurai K, Shimada H, Hayashi T, Tsukihara T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Feb 1;65(Pt 2):80-3. doi: 10.1107/S1744309108044114. Epub 2009 Jan 31.

PMID:
19193991
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect.

Vidakovic M, Sligar SG, Li H, Poulos TL.

Biochemistry. 1998 Jun 30;37(26):9211-9.

PMID:
9649301
[PubMed - indexed for MEDLINE]
20.

Optical detection of cytochrome P450 by sensitizer-linked substrates.

Dmochowski IJ, Crane BR, Wilker JJ, Winkler JR, Gray HB.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):12987-90.

PMID:
10557259
[PubMed - indexed for MEDLINE]
Free PMC Article
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