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Results: 1 to 20 of 88

1.

The blooming of the French lilac.

Witters LA.

J Clin Invest. 2001 Oct;108(8):1105-7. Review. No abstract available.

PMID:
11602616
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes.

Taylor EB, Goodyear LJ.

Curr Diab Rep. 2007 Dec;7(6):399-401. No abstract available.

PMID:
18254999
[PubMed - indexed for MEDLINE]
3.

Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.

Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear LJ.

Diabetes. 2002 Jul;51(7):2074-81.

PMID:
12086935
[PubMed - indexed for MEDLINE]
Free Article
4.

Medicine. Cancer-suppressing enzyme adds a link to type 2 diabetes.

Marx J.

Science. 2005 Nov 25;310(5752):1259. No abstract available.

PMID:
16311305
[PubMed - indexed for MEDLINE]
5.

Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects.

Luna V, Casauban L, Sajan MP, Gomez-Daspet J, Powe JL, Miura A, Rivas J, Standaert ML, Farese RV.

Diabetologia. 2006 Feb;49(2):375-82. Epub 2006 Jan 5.

PMID:
16395615
[PubMed - indexed for MEDLINE]
6.

Neither LKB1 nor AMPK are the direct targets of metformin.

Hardie DG.

Gastroenterology. 2006 Sep;131(3):973; author reply 974-5. No abstract available.

PMID:
16952573
[PubMed - indexed for MEDLINE]
7.

Cancer research. Cancer prevention with a diabetes pill?

Taubes G.

Science. 2012 Jan 6;335(6064):29. doi: 10.1126/science.335.6064.29. No abstract available.

PMID:
22223788
[PubMed - indexed for MEDLINE]
8.

Role of AMP-activated protein kinase in mechanism of metformin action.

Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE.

J Clin Invest. 2001 Oct;108(8):1167-74.

PMID:
11602624
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

AMP-activated protein kinase and type 2 diabetes.

Musi N.

Curr Med Chem. 2006;13(5):583-9. Review.

PMID:
16515522
[PubMed - indexed for MEDLINE]
10.

Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes.

Musi N, Goodyear LJ.

Curr Drug Targets Immune Endocr Metabol Disord. 2002 Jul;2(2):119-27. Review.

PMID:
12476786
[PubMed - indexed for MEDLINE]
11.

AMP-activated protein kinase: a target for drugs both ancient and modern.

Hardie DG, Ross FA, Hawley SA.

Chem Biol. 2012 Oct 26;19(10):1222-36. doi: 10.1016/j.chembiol.2012.08.019. Review.

PMID:
23102217
[PubMed - indexed for MEDLINE]
Free Article
12.

[From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target].

Foretz M, Guigas B, Viollet B.

Med Sci (Paris). 2006 Apr;22(4):348-50. French. No abstract available.

PMID:
16597397
[PubMed - indexed for MEDLINE]
Free Article
13.

Non-insulin dependent diabetes mellitus: present therapies and new drug targets.

Das SK, Chakrabarti R.

Mini Rev Med Chem. 2005 Nov;5(11):1019-34. Review.

PMID:
16307531
[PubMed - indexed for MEDLINE]
14.

Metformin therapy in a transgenic mouse model of Huntington's disease.

Ma TC, Buescher JL, Oatis B, Funk JA, Nash AJ, Carrier RL, Hoyt KR.

Neurosci Lett. 2007 Jan 10;411(2):98-103. Epub 2006 Nov 15.

PMID:
17110029
[PubMed - indexed for MEDLINE]
15.

Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target.

Boyle JG, Salt IP, McKay GA.

Diabet Med. 2010 Oct;27(10):1097-106. doi: 10.1111/j.1464-5491.2010.03098.x. Review.

PMID:
20854376
[PubMed - indexed for MEDLINE]
16.

LKB1: a sweet side to Peutz-Jeghers syndrome?

Carling D.

Trends Mol Med. 2006 Apr;12(4):144-7. Epub 2006 Mar 10. Review.

PMID:
16530014
[PubMed - indexed for MEDLINE]
17.

Overcoming insulin resistance with CNTF.

Ahima RS.

Nat Med. 2006 May;12(5):511-2. No abstract available.

PMID:
16675997
[PubMed - indexed for MEDLINE]
18.

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism.

Hawley SA, Gadalla AE, Olsen GS, Hardie DG.

Diabetes. 2002 Aug;51(8):2420-5.

PMID:
12145153
[PubMed - indexed for MEDLINE]
Free Article
19.

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

Um JH, Yang S, Yamazaki S, Kang H, Viollet B, Foretz M, Chung JH.

J Biol Chem. 2007 Jul 20;282(29):20794-8. Epub 2007 May 24.

PMID:
17525164
[PubMed - indexed for MEDLINE]
Free Article
20.

AMP-activated protein kinase: possible target for treatment of type 2 diabetes.

Winder WW.

Diabetes Technol Ther. 2000 Autumn;2(3):441-8. Review.

PMID:
11467346
[PubMed - indexed for MEDLINE]

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