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Results: 1 to 20 of 2435

1.

Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group.

Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V.

Arthritis Rheum. 2001 Sep;44(9):1984-92.

PMID:
11592358
[PubMed - indexed for MEDLINE]
Free Article
2.

Treatment with leflunomide slows radiographic progression of rheumatoid arthritis: results from three randomized controlled trials of leflunomide in patients with active rheumatoid arthritis. Leflunomide Rheumatoid Arthritis Investigators Group.

Sharp JT, Strand V, Leung H, Hurley F, Loew-Friedrich I.

Arthritis Rheum. 2000 Mar;43(3):495-505. Erratum in: Arthritis Rheum 2000 Jun;43(6):1345.

PMID:
10728741
[PubMed - indexed for MEDLINE]
Free Article
3.

Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group.

Strand V, Cohen S, Schiff M, Weaver A, Fleischmann R, Cannon G, Fox R, Moreland L, Olsen N, Furst D, Caldwell J, Kaine J, Sharp J, Hurley F, Loew-Friedrich I.

Arch Intern Med. 1999 Nov 22;159(21):2542-50.

PMID:
10573044
[PubMed - indexed for MEDLINE]
4.

Physical function and health related quality of life: analysis of 2-year data from randomized, controlled studies of leflunomide, sulfasalazine, or methotrexate in patients with active rheumatoid arthritis.

Strand V, Scott DL, Emery P, Kalden JR, Smolen JS, Cannon GW, Tugwell P, Crawford B; Leflunomide Rheumatoid Arthritis Investigators Groups.

J Rheumatol. 2005 Apr;32(4):590-601.

PMID:
15801012
[PubMed - indexed for MEDLINE]
5.

Preliminary evaluation in rheumatoid arthritis activity in patients treated with TNF-alpha blocker plus methotrexate versus methotrexate or leflunomide alone.

Wisłowska M, Jakubicz D.

Rheumatol Int. 2007 May;27(7):641-7. Epub 2007 Jan 18.

PMID:
17235556
[PubMed - indexed for MEDLINE]
6.

Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial.

Kremer J, Genovese M, Cannon GW, Caldwell J, Cush J, Furst DE, Luggen M, Keystone E, Bathon J, Kavanaugh A, Ruderman E, Coleman P, Curtis D, Kopp E, Kantor S, Weisman M, Waltuck J, Lindsley HB, Markenson J, Crawford B, Fernando I, Simpson K, Strand V.

J Rheumatol. 2004 Aug;31(8):1521-31.

PMID:
15290730
[PubMed - indexed for MEDLINE]
7.

Improved functional ability in patients with rheumatoid arthritis--longterm treatment with leflunomide versus sulfasalazine. European Leflunomide Study Group.

Kalden JR, Scott DL, Smolen JS, Schattenkirchner M, Rozman B, Williams BD, Kvien TK, Jones P, Williams RB, Oed C, Rosenburg R; European Leflunomide Study Group.

J Rheumatol. 2001 Sep;28(9):1983-91. Erratum in: J Rheumatol 2002 Jan;29(1):205.

PMID:
11550964
[PubMed - indexed for MEDLINE]
8.

Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate.

Maini RN, Breedveld FC, Kalden JR, Smolen JS, Furst D, Weisman MH, St Clair EW, Keenan GF, van der Heijde D, Marsters PA, Lipsky PE; Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group.

Arthritis Rheum. 2004 Apr;50(4):1051-65.

PMID:
15077287
[PubMed - indexed for MEDLINE]
Free Article
9.

Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.

Kremer JM, Genovese MC, Cannon GW, Caldwell JR, Cush JJ, Furst DE, Luggen ME, Keystone E, Weisman MH, Bensen WM, Kaine JL, Ruderman EM, Coleman P, Curtis DL, Kopp EJ, Kantor SM, Waltuck J, Lindsley HB, Markenson JA, Strand V, Crawford B, Fernando I, Simpson K, Bathon JM.

Ann Intern Med. 2002 Nov 5;137(9):726-33.

PMID:
12416946
[PubMed - indexed for MEDLINE]
10.

Function and health-related quality of life: results from a randomized controlled trial of leflunomide versus methotrexate or placebo in patients with active rheumatoid arthritis. Leflunomide Rheumatoid Arthritis Investigators Group.

Strand V, Tugwell P, Bombardier C, Maetzel A, Crawford B, Dorrier C, Thompson A, Wells G.

Arthritis Rheum. 1999 Sep;42(9):1870-8.

PMID:
10513801
[PubMed - indexed for MEDLINE]
Free Article
12.

Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes.

Genovese MC, Bathon JM, Martin RW, Fleischmann RM, Tesser JR, Schiff MH, Keystone EC, Wasko MC, Moreland LW, Weaver AL, Markenson J, Cannon GW, Spencer-Green G, Finck BK.

Arthritis Rheum. 2002 Jun;46(6):1443-50.

PMID:
12115173
[PubMed - indexed for MEDLINE]
Free Article
13.

Toward a definition and method of assessment of treatment failure and treatment effectiveness: the case of leflunomide versus methotrexate.

Wolfe F, Michaud K, Stephenson B, Doyle J.

J Rheumatol. 2003 Aug;30(8):1725-32.

PMID:
12913927
[PubMed - indexed for MEDLINE]
14.

Leflunomide, a new disease-modifying drug for treating active rheumatoid arthritis in methotrexate-controlled phase II clinical trial.

Bao C, Chen S, Gu Y, Lao Z, Ni L, Yu Q, Xu J, Li X, Liu J, Sun L, He P, Ma J, Xu S, Ding C.

Chin Med J (Engl). 2003 Aug;116(8):1228-34.

PMID:
12935395
[PubMed - indexed for MEDLINE]
15.

Efficacy and safety of leflunomide 10 mg versus 20 mg once daily in patients with active rheumatoid arthritis: multinational double-blind, randomized trial.

Poór G, Strand V; Leflunomide Multinational Study Group.

Rheumatology (Oxford). 2004 Jun;43(6):744-9. Epub 2004 Mar 16.

PMID:
15026583
[PubMed - indexed for MEDLINE]
Free Article
16.

[Security of the combined treatment of methotrexate and leflunomide in patients with rheumatoid arthritis].

Nesa L, Gobbi C, Alba P, Exeni I, Babini A, Albiero E.

Rev Fac Cien Med Univ Nac Cordoba. 2007;64(4):109-14. Spanish.

PMID:
19928400
[PubMed - indexed for MEDLINE]
18.

Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial.

Braun J, Kästner P, Flaxenberg P, Währisch J, Hanke P, Demary W, von Hinüber U, Rockwitz K, Heitz W, Pichlmeier U, Guimbal-Schmolck C, Brandt A; MC-MTX.6/RH Study Group.

Arthritis Rheum. 2008 Jan;58(1):73-81. doi: 10.1002/art.23144.

PMID:
18163521
[PubMed - indexed for MEDLINE]
Free Article
19.

Reduction of the efficacy of methotrexate by the use of folic acid: post hoc analysis from two randomized controlled studies.

Khanna D, Park GS, Paulus HE, Simpson KM, Elashoff D, Cohen SB, Emery P, Dorrier C, Furst DE.

Arthritis Rheum. 2005 Oct;52(10):3030-8.

PMID:
16200612
[PubMed - indexed for MEDLINE]
Free Article
20.

Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial.

van der Heijde D, Klareskog L, Rodriguez-Valverde V, Codreanu C, Bolosiu H, Melo-Gomes J, Tornero-Molina J, Wajdula J, Pedersen R, Fatenejad S; TEMPO Study Investigators.

Arthritis Rheum. 2006 Apr;54(4):1063-74.

PMID:
16572441
[PubMed - indexed for MEDLINE]
Free Article
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