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Results: 1 to 20 of 154

1.

Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT.

McCormack EA, Llorca O, Carrascosa JL, Valpuesta JM, Willison KR.

J Struct Biol. 2001 Aug;135(2):198-204.

PMID:
11580269
[PubMed - indexed for MEDLINE]
2.
3.

Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin.

Llorca O, Martín-Benito J, Gómez-Puertas P, Ritco-Vonsovici M, Willison KR, Carrascosa JL, Valpuesta JM.

J Struct Biol. 2001 Aug;135(2):205-18.

PMID:
11580270
[PubMed - indexed for MEDLINE]
4.

Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin.

Hynes GM, Willison KR.

J Biol Chem. 2000 Jun 23;275(25):18985-94.

PMID:
10748209
[PubMed - indexed for MEDLINE]
Free Article
5.

Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin.

Kubota H, Hynes G, Carne A, Ashworth A, Willison K.

Curr Biol. 1994 Feb 1;4(2):89-99.

PMID:
7953530
[PubMed - indexed for MEDLINE]
6.

Eukaryotic type II chaperonin CCT interacts with actin through specific subunits.

Llorca O, McCormack EA, Hynes G, Grantham J, Cordell J, Carrascosa JL, Willison KR, Fernandez JJ, Valpuesta JM.

Nature. 1999 Dec 9;402(6762):693-6.

PMID:
10604479
[PubMed - indexed for MEDLINE]
7.

Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations.

Llorca O, Martín-Benito J, Ritco-Vonsovici M, Grantham J, Hynes GM, Willison KR, Carrascosa JL, Valpuesta JM.

EMBO J. 2000 Nov 15;19(22):5971-9.

PMID:
11080144
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Actin interacts with CCT via discrete binding sites: a binding transition-release model for CCT-mediated actin folding.

Neirynck K, Waterschoot D, Vandekerckhove J, Ampe C, Rommelaere H.

J Mol Biol. 2006 Jan 6;355(1):124-38. Epub 2005 Nov 9.

PMID:
16300788
[PubMed - indexed for MEDLINE]
9.

Quantitative actin folding reactions using yeast CCT purified via an internal tag in the CCT3/gamma subunit.

Pappenberger G, McCormack EA, Willison KR.

J Mol Biol. 2006 Jul 7;360(2):484-96. Epub 2006 May 17.

PMID:
16762366
[PubMed - indexed for MEDLINE]
10.

Newly-synthesized beta-tubulin demonstrates domain-specific interactions with the cytosolic chaperonin.

Dobrzynski JK, Sternlicht ML, Farr GW, Sternlicht H.

Biochemistry. 1996 Dec 10;35(49):15870-82.

PMID:
8961952
[PubMed - indexed for MEDLINE]
11.

Partial occlusion of both cavities of the eukaryotic chaperonin with antibody has no effect upon the rates of beta-actin or alpha-tubulin folding.

Grantham J, Llorca O, Valpuesta JM, Willison KR.

J Biol Chem. 2000 Feb 18;275(7):4587-91.

PMID:
10671484
[PubMed - indexed for MEDLINE]
Free Article
12.

Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system.

Siegers K, Waldmann T, Leroux MR, Grein K, Shevchenko A, Schiebel E, Hartl FU.

EMBO J. 1999 Jan 4;18(1):75-84.

PMID:
9878052
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains.

Kim S, Willison KR, Horwich AL.

Trends Biochem Sci. 1994 Dec;19(12):543-8. Review.

PMID:
7846767
[PubMed - indexed for MEDLINE]
14.

Structure and function of a protein folding machine: the eukaryotic cytosolic chaperonin CCT.

Valpuesta JM, Martín-Benito J, Gómez-Puertas P, Carrascosa JL, Willison KR.

FEBS Lett. 2002 Oct 2;529(1):11-6. Review.

PMID:
12354605
[PubMed - indexed for MEDLINE]
Free Article
15.

Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT.

Dunn AY, Melville MW, Frydman J.

J Struct Biol. 2001 Aug;135(2):176-84. Review.

PMID:
11580267
[PubMed - indexed for MEDLINE]
16.

Evidence that beta-tubulin induces a conformation change in the cytosolic chaperonin which stabilizes binding: implications for the mechanism of action.

Dobrzynski JK, Sternlicht ML, Peng I, Farr GW, Sternlicht H.

Biochemistry. 2000 Apr 11;39(14):3988-4003.

PMID:
10747787
[PubMed - indexed for MEDLINE]
17.

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding.

Feldman DE, Spiess C, Howard DE, Frydman J.

Mol Cell. 2003 Nov;12(5):1213-24.

PMID:
14636579
[PubMed - indexed for MEDLINE]
Free Article
18.

PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates.

Stirling PC, Cuéllar J, Alfaro GA, El Khadali F, Beh CT, Valpuesta JM, Melki R, Leroux MR.

J Biol Chem. 2006 Mar 17;281(11):7012-21. Epub 2006 Jan 16.

PMID:
16415341
[PubMed - indexed for MEDLINE]
Free Article
19.

The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins.

Rommelaere H, De Neve M, Melki R, Vandekerckhove J, Ampe C.

Biochemistry. 1999 Mar 16;38(11):3246-57.

PMID:
10079067
[PubMed - indexed for MEDLINE]
20.

Origin and evolution of eukaryotic chaperonins: phylogenetic evidence for ancient duplications in CCT genes.

Archibald JM, Logsdon JM Jr, Doolittle WF.

Mol Biol Evol. 2000 Oct;17(10):1456-66.

PMID:
11018153
[PubMed - indexed for MEDLINE]
Free Article

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